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• W3195295267 abstract "High-definition intravascular ultrasound (HD-IVUS) utilizing more than 80 MHz frequency to assess atherosclerotic plaque, can theoretically achieve an axial resolution of less than <inline-formula xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink> <tex-math notation=LaTeX>$20~mu text{m}$ </tex-math></inline-formula> . However, the blood is a high-attenuation source at high frequency, which would affect the imaging quality. There has been no research evaluating the blood-induced influence on HD-IVUS imaging. And whether a temporary removal of blood is needed for HD-IVUS is unknown. In this study, an ultrahigh-frequency (100 MHz) ultrasound transducer was developed to evaluate the blood-induced attenuation for HD-IVUS imaging. A series of tungsten-wire phantom images in saline and blood at varying hematocrits were obtained. The images showed that blood did influence the ultrahigh-frequency imaging quality greatly. The signal-to-noise ratio (SNR) decrease by 71.7% in porcine whole blood compared to that in saline at the same depth of 2.3 mm. Moreover, the potential flushing schemes for HD-IVUS were studied in varying hematocrits. Three flushing agents commonly used in intravascular optical coherence tomography (IV-OCT) were investigated, including iohexol, mannitol, and dextran 5% and saline as the control group. The attenuation of blood in varying hematocrits/flushing agents was measured from 90 to 110 MHz. The result indicated dextran 5% was a suitable flushing agent for HD-IVUS due to its less signal attenuation compared to others." @default.
• W3195295267 created "2021-08-30" @default.
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• W3195295267 date "2022-01-01" @default.
• W3195295267 modified "2023-10-17" @default.
• W3195295267 title "Evaluation of Blood Induced Influence for High-Definition Intravascular Ultrasound (HD-IVUS)" @default.
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• W3195295267 doi "https://doi.org/10.1109/tuffc.2021.3108163" @default.
• W3195295267 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34437062" @default.
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