Matches in SemOpenAlex for { <https://semopenalex.org/work/W3195355576> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W3195355576 abstract "BACKGROUND AND AIM: Para-dichlorobenzene (p-DCB) is a chlorinated volatile organic compound that is commonly found in the household and public buildings due to its widespread use as pest repellent and deodorant. There has been an increasing concern about the potential effect of p-DCB on endocrine and metabolic function. Little is known about the relationship between p-DCB exposure and endocrine-related cancers. METHODS: A nationally representative subsample of 4459 women, aged 20 years or older, in the 2003-2016 National Health and Nutrition Examination Survey was analyzed for the association between urinary concentrations of 2,5-dichlorophenol (2,5-DCP), the primary metabolite of p-DCB, and endocrine-related female cancers (including breast, ovarian, and uterine cancers) using multivariate logistic regression models, adjusting for potential confounders. RESULTS:Of the study participants, 202 women (weighted prevalence, 4.20%) reported being diagnosed with any of these endocrine-related reproductive cancers. Women with reproductive cancers showed a statistically significant increase in urinary 2,5-DCP concentrations (weighted geometric mean, 7.97 vs. 5.84 µg/g creatinine; p0.0001) as compared to women without these cancers. After adjusting for potential confounders, we found that women in the intermediate (1.94-28.10 µg/g creatinine) and higher quartiles (≥28.10 µg/g creatinine) of 2,5-DCP had significantly increased odds of endocrine-related reproductive cancers with the odds ratio of 1.66 (95% CI: 1.02, 2.71) and 1.89 (95% CI: 1.08, 3.29), respectively, as compared with those in the lower quartile. CONCLUSIONS:Our study demonstrates a potential relationship between p-DCB exposure, measured as urinary 2,5-DCP, and endocrine-related reproductive cancers in US women. Additional studies would further explore these interactions and elucidate the pathogenesis of endocrine-related female cancers associated with p-DCB exposure. KEYWORDS: 2,5-dichlorophenol, endocrine-related reproductive cancers, para-dichlorobenzene, prevalence; women" @default.
- W3195355576 created "2021-08-30" @default.
- W3195355576 creator A5005496888 @default.
- W3195355576 creator A5019773472 @default.
- W3195355576 creator A5043719050 @default.
- W3195355576 date "2021-08-23" @default.
- W3195355576 modified "2023-09-24" @default.
- W3195355576 title "Urinary concentrations of 2,5-dichlorophenol and prevalent endocrine-related female cancers" @default.
- W3195355576 doi "https://doi.org/10.1289/isee.2021.p-302" @default.
- W3195355576 hasPublicationYear "2021" @default.
- W3195355576 type Work @default.
- W3195355576 sameAs 3195355576 @default.
- W3195355576 citedByCount "0" @default.
- W3195355576 crossrefType "journal-article" @default.
- W3195355576 hasAuthorship W3195355576A5005496888 @default.
- W3195355576 hasAuthorship W3195355576A5019773472 @default.
- W3195355576 hasAuthorship W3195355576A5043719050 @default.
- W3195355576 hasConcept C126322002 @default.
- W3195355576 hasConcept C134018914 @default.
- W3195355576 hasConcept C151956035 @default.
- W3195355576 hasConcept C156957248 @default.
- W3195355576 hasConcept C159641895 @default.
- W3195355576 hasConcept C2779874844 @default.
- W3195355576 hasConcept C2780306776 @default.
- W3195355576 hasConcept C2908647359 @default.
- W3195355576 hasConcept C29456083 @default.
- W3195355576 hasConcept C42407357 @default.
- W3195355576 hasConcept C44249647 @default.
- W3195355576 hasConcept C46699223 @default.
- W3195355576 hasConcept C68443243 @default.
- W3195355576 hasConcept C71315377 @default.
- W3195355576 hasConcept C71924100 @default.
- W3195355576 hasConcept C77350462 @default.
- W3195355576 hasConcept C99454951 @default.
- W3195355576 hasConceptScore W3195355576C126322002 @default.
- W3195355576 hasConceptScore W3195355576C134018914 @default.
- W3195355576 hasConceptScore W3195355576C151956035 @default.
- W3195355576 hasConceptScore W3195355576C156957248 @default.
- W3195355576 hasConceptScore W3195355576C159641895 @default.
- W3195355576 hasConceptScore W3195355576C2779874844 @default.
- W3195355576 hasConceptScore W3195355576C2780306776 @default.
- W3195355576 hasConceptScore W3195355576C2908647359 @default.
- W3195355576 hasConceptScore W3195355576C29456083 @default.
- W3195355576 hasConceptScore W3195355576C42407357 @default.
- W3195355576 hasConceptScore W3195355576C44249647 @default.
- W3195355576 hasConceptScore W3195355576C46699223 @default.
- W3195355576 hasConceptScore W3195355576C68443243 @default.
- W3195355576 hasConceptScore W3195355576C71315377 @default.
- W3195355576 hasConceptScore W3195355576C71924100 @default.
- W3195355576 hasConceptScore W3195355576C77350462 @default.
- W3195355576 hasConceptScore W3195355576C99454951 @default.
- W3195355576 hasIssue "1" @default.
- W3195355576 hasLocation W31953555761 @default.
- W3195355576 hasOpenAccess W3195355576 @default.
- W3195355576 hasPrimaryLocation W31953555761 @default.
- W3195355576 hasRelatedWork W12357974 @default.
- W3195355576 hasRelatedWork W12467399 @default.
- W3195355576 hasRelatedWork W13051375 @default.
- W3195355576 hasRelatedWork W17666019 @default.
- W3195355576 hasRelatedWork W20729663 @default.
- W3195355576 hasRelatedWork W7570991 @default.
- W3195355576 hasRelatedWork W8175496 @default.
- W3195355576 hasRelatedWork W8875811 @default.
- W3195355576 hasRelatedWork W9037821 @default.
- W3195355576 hasRelatedWork W10176059 @default.
- W3195355576 hasVolume "2021" @default.
- W3195355576 isParatext "false" @default.
- W3195355576 isRetracted "false" @default.
- W3195355576 magId "3195355576" @default.
- W3195355576 workType "article" @default.