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- W3195678983 abstract "In most diploid cells, autosomal genes are equallyexpressed from the paternal and maternal alleles resulting inbiallelic expression. However, as an exception, there exists asmall number of genes that show a pattern of monoallelic orbiased-allele expression based on the allele’s parent-of-origin.This phenomenon is termed genomic imprinting and is an evolutionaryparadox. The best explanation for imprinting is David Haig'skinship theory, which hypothesizes that monoallelic gene expressionis largely the result of evolutionary conflict between males andfemales over maternal involvement in their offspring. One previousRNAseq study has investigated the presence of parent-of-origineffects, or imprinting, in the parasitic jewel wasp Nasoniavitripennis (N. vitripennis) and its sister species Nasoniagiraulti (N. giraulti) to test the predictions of kinship theory ina non-eusocial species for comparison to a eusocial one. In orderto continue to tease apart the connection between social andeusocial Hymenoptera, this study proposed a similar RNAseq studythat attempted to reproduce these results in unique samples ofreciprocal F1 Nasonia hybrids. Building a pseudo N. giraultireference genome, differences were observed when aligning RNAseqreads to a N. vitripennis reference genome compared to aligningreads to a pseudo N. giraulti reference. As well, no evidence forparent-of-origin or imprinting patterns in adult Nasonia werefound. These results demonstrated a species-of-origin effect.Importantly, the study continued to build a repository of supportwith the aim to elucidate the mechanisms behind imprinting in anexcellent epigenetic model species, as it can also help withunderstanding the phenomenon of imprinting in complex humandiseases." @default.
- W3195678983 created "2021-08-30" @default.
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- W3195678983 date "2019-01-01" @default.
- W3195678983 modified "2023-09-23" @default.
- W3195678983 title "A Search for Parent-of-origin Effects in the Parasitoid Jewel Wasp Nasonia vitripennis" @default.
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