Matches in SemOpenAlex for { <https://semopenalex.org/work/W3195744933> ?p ?o ?g. }
- W3195744933 endingPage "100235" @default.
- W3195744933 startingPage "100235" @default.
- W3195744933 abstract "Synthetic biology has been developing rapidly in the last decade and is attracting increasing attention from many plant biologists. The production of high-value plant-specific secondary metabolites is, however, limited mostly to microbes. This is potentially problematic because of incorrect post-translational modification of proteins and differences in protein micro-compartmentalization, substrate availability, chaperone availability, product toxicity, and cytochrome p450 reductase enzymes. Unlike other heterologous systems, plant cells may be a promising alternative for the production of high-value metabolites. Several commercial plant suspension cell cultures from different plant species have been used successfully to produce valuable metabolites in a safe, low cost, and environmentally friendly manner. However, few metabolites are currently being biosynthesized using plant platforms, with the exception of the natural pigment anthocyanin. Both Arabidopsis thaliana and Nicotiana tabacum cell cultures can be developed by multiple gene transformations and CRISPR-Cas9 genome editing. Given that the introduction of heterologous biosynthetic pathways into Arabidopsis and N. tabacum is not widely used, the biosynthesis of foreign metabolites is currently limited; however, therein lies great potential. Here, we discuss the exemplary use of plant cell cultures and prospects for using A. thaliana and N. tabacum cell cultures to produce valuable plant-specific metabolites." @default.
- W3195744933 created "2021-08-30" @default.
- W3195744933 creator A5011962101 @default.
- W3195744933 creator A5024677866 @default.
- W3195744933 creator A5065618924 @default.
- W3195744933 creator A5082852942 @default.
- W3195744933 date "2021-09-01" @default.
- W3195744933 modified "2023-10-16" @default.
- W3195744933 title "Plant cell cultures as heterologous bio-factories for secondary metabolite production" @default.
- W3195744933 cites W1481493081 @default.
- W3195744933 cites W1501660433 @default.
- W3195744933 cites W1529284100 @default.
- W3195744933 cites W1568903637 @default.
- W3195744933 cites W1583862192 @default.
- W3195744933 cites W170344441 @default.
- W3195744933 cites W1764544009 @default.
- W3195744933 cites W1767127367 @default.
- W3195744933 cites W1817322519 @default.
- W3195744933 cites W1927737439 @default.
- W3195744933 cites W1968391529 @default.
- W3195744933 cites W1974842306 @default.
- W3195744933 cites W1983071204 @default.
- W3195744933 cites W1988527492 @default.
- W3195744933 cites W1990110046 @default.
- W3195744933 cites W1997212522 @default.
- W3195744933 cites W2002006547 @default.
- W3195744933 cites W2002217310 @default.
- W3195744933 cites W2004778544 @default.
- W3195744933 cites W2005092495 @default.
- W3195744933 cites W2005275397 @default.
- W3195744933 cites W2006559324 @default.
- W3195744933 cites W2019460535 @default.
- W3195744933 cites W2020157885 @default.
- W3195744933 cites W2021274204 @default.
- W3195744933 cites W2026942532 @default.
- W3195744933 cites W2032896564 @default.
- W3195744933 cites W2040136938 @default.
- W3195744933 cites W2055906347 @default.
- W3195744933 cites W2062573403 @default.
- W3195744933 cites W2062736124 @default.
- W3195744933 cites W2064441463 @default.
- W3195744933 cites W2069097240 @default.
- W3195744933 cites W2071654564 @default.
- W3195744933 cites W2078355959 @default.
- W3195744933 cites W2079042867 @default.
- W3195744933 cites W2092198719 @default.
- W3195744933 cites W2097039679 @default.
- W3195744933 cites W2104082467 @default.
- W3195744933 cites W2118464978 @default.
- W3195744933 cites W2119179068 @default.
- W3195744933 cites W2136568972 @default.
- W3195744933 cites W2140370795 @default.
- W3195744933 cites W2140555525 @default.
- W3195744933 cites W2141170384 @default.
- W3195744933 cites W2150207014 @default.
- W3195744933 cites W2158215557 @default.
- W3195744933 cites W2161914035 @default.
- W3195744933 cites W2166416102 @default.
- W3195744933 cites W2171911398 @default.
- W3195744933 cites W2186855430 @default.
- W3195744933 cites W2208335719 @default.
- W3195744933 cites W2344372370 @default.
- W3195744933 cites W2344648730 @default.
- W3195744933 cites W2466635249 @default.
- W3195744933 cites W2468942787 @default.
- W3195744933 cites W2505875603 @default.
- W3195744933 cites W2529361162 @default.
- W3195744933 cites W2538786612 @default.
- W3195744933 cites W2540953637 @default.
- W3195744933 cites W2549799095 @default.
- W3195744933 cites W2569472062 @default.
- W3195744933 cites W2574251228 @default.
- W3195744933 cites W2581239899 @default.
- W3195744933 cites W2616118570 @default.
- W3195744933 cites W2763042654 @default.
- W3195744933 cites W2765351619 @default.
- W3195744933 cites W2768973916 @default.
- W3195744933 cites W2784202856 @default.
- W3195744933 cites W2785014466 @default.
- W3195744933 cites W2791144802 @default.
- W3195744933 cites W2796818985 @default.
- W3195744933 cites W2797202858 @default.
- W3195744933 cites W2802491818 @default.
- W3195744933 cites W2802820253 @default.
- W3195744933 cites W2805730414 @default.
- W3195744933 cites W2808816533 @default.
- W3195744933 cites W2809168619 @default.
- W3195744933 cites W2809653775 @default.
- W3195744933 cites W2810159725 @default.
- W3195744933 cites W2887326842 @default.
- W3195744933 cites W2900498998 @default.
- W3195744933 cites W2901159587 @default.
- W3195744933 cites W2909763373 @default.
- W3195744933 cites W2915064426 @default.
- W3195744933 cites W2972288326 @default.
- W3195744933 cites W2973523635 @default.
- W3195744933 cites W2981510951 @default.
- W3195744933 cites W2981582835 @default.