FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3195953400> ?p ?o ?g. }

• W3195953400 endingPage "164" @default.
• W3195953400 startingPage "155" @default.
• W3195953400 abstract "To examine the efficacy and safety of antiepileptic drugs (AED) for the inpatient treatment of patients with moderate to severe alcohol withdrawal syndrome (AWS).We searched in databases and gray literature to include randomized controlled clinical trials in adults that compare the use of AED versus placebo or any other medication. Studies that did not specify severity or were performed on an outpatient basis were excluded. The outcomes were improvement of symptoms, delirium tremens, seizures and adverse events. Two researchers independently selected the references, extracted the data and assessed the risk of bias. A qualitative synthesis was made and, when the heterogeneity was mild or moderate, a meta-analysis was performed. The quality of the evidence obtained was evaluated with the Grading of Recommendations Assessment, Development and Evaluation tool.In total, 26 studies with 1709 patients were included. No benefit is described in withdrawal syndrome severity measured by scales or in the development of delirium tremens. The only possible meta-analysis showed that there are no differences in the incidence of seizures (risk ratio [RR] = 1.0; confidence interval (CI) 95% 0.76-1.33), even when compared with placebo (RR = 0.95; CI95% 0.57-1.57). There were also no differences in adverse events, although a higher proportion of some mild cases were described with the use of carbamazepine and valproic acid.The routine use of AED is not suggested in the treatment of patients with moderate or severe AWS unless indicated for comorbidity (weak recommendation against using moderate quality of evidence)." @default.
• W3195953400 created "2021-08-30" @default.
• W3195953400 creator A5014151200 @default.
• W3195953400 creator A5060695530 @default.
• W3195953400 creator A5061359883 @default.
• W3195953400 date "2021-08-13" @default.
• W3195953400 modified "2023-10-14" @default.
• W3195953400 title "Efficacy and Safety of Anticonvulsants for the Inpatient Treatment of Alcohol Withdrawal Syndrome: A Systematic Review and Meta-analysis" @default.
• W3195953400 cites W106360673 @default.
• W3195953400 cites W128150697 @default.
• W3195953400 cites W1611330866 @default.
• W3195953400 cites W1763846455 @default.
• W3195953400 cites W1913553265 @default.
• W3195953400 cites W1922131974 @default.
• W3195953400 cites W1968498714 @default.
• W3195953400 cites W1993430659 @default.
• W3195953400 cites W1996882512 @default.
• W3195953400 cites W1997390821 @default.
• W3195953400 cites W2003605191 @default.
• W3195953400 cites W2011432686 @default.
• W3195953400 cites W2013815042 @default.
• W3195953400 cites W2022936071 @default.
• W3195953400 cites W2023519313 @default.
• W3195953400 cites W2025352563 @default.
• W3195953400 cites W2028498079 @default.
• W3195953400 cites W2034193544 @default.
• W3195953400 cites W2035865572 @default.
• W3195953400 cites W2044898423 @default.
• W3195953400 cites W2046864229 @default.
• W3195953400 cites W2051678494 @default.
• W3195953400 cites W2052378919 @default.
• W3195953400 cites W2056984976 @default.
• W3195953400 cites W2059831180 @default.
• W3195953400 cites W2072754684 @default.
• W3195953400 cites W2077979665 @default.
• W3195953400 cites W2080477042 @default.
• W3195953400 cites W2089272715 @default.
• W3195953400 cites W2089724708 @default.
• W3195953400 cites W2094293766 @default.
• W3195953400 cites W2094885104 @default.
• W3195953400 cites W2095103357 @default.
• W3195953400 cites W2108783826 @default.
• W3195953400 cites W2123705832 @default.
• W3195953400 cites W2147343760 @default.
• W3195953400 cites W2149278215 @default.
• W3195953400 cites W2181357053 @default.
• W3195953400 cites W2336056834 @default.
• W3195953400 cites W2397063274 @default.
• W3195953400 cites W2623296778 @default.
• W3195953400 cites W2748574299 @default.
• W3195953400 cites W2750832548 @default.
• W3195953400 cites W2998799567 @default.
• W3195953400 cites W3109711678 @default.
• W3195953400 cites W4234215700 @default.
• W3195953400 cites W4241680393 @default.
• W3195953400 cites W63165017 @default.
• W3195953400 doi "https://doi.org/10.1093/alcalc/agab057" @default.
• W3195953400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34396386" @default.
• W3195953400 hasPublicationYear "2021" @default.
• W3195953400 type Work @default.
• W3195953400 sameAs 3195953400 @default.
• W3195953400 citedByCount "4" @default.
• W3195953400 countsByYear W31959534002022 @default.
• W3195953400 countsByYear W31959534002023 @default.
• W3195953400 crossrefType "journal-article" @default.
• W3195953400 hasAuthorship W3195953400A5014151200 @default.
• W3195953400 hasAuthorship W3195953400A5060695530 @default.
• W3195953400 hasAuthorship W3195953400A5061359883 @default.
• W3195953400 hasConcept C118552586 @default.
• W3195953400 hasConcept C126322002 @default.
• W3195953400 hasConcept C142724271 @default.
• W3195953400 hasConcept C168563851 @default.
• W3195953400 hasConcept C185592680 @default.
• W3195953400 hasConcept C197934379 @default.
• W3195953400 hasConcept C204787440 @default.
• W3195953400 hasConcept C27081682 @default.
• W3195953400 hasConcept C2776901510 @default.
• W3195953400 hasConcept C2779753318 @default.
• W3195953400 hasConcept C2780873584 @default.
• W3195953400 hasConcept C2781066024 @default.
• W3195953400 hasConcept C42219234 @default.
• W3195953400 hasConcept C44249647 @default.
• W3195953400 hasConcept C55493867 @default.
• W3195953400 hasConcept C71924100 @default.
• W3195953400 hasConcept C82789193 @default.
• W3195953400 hasConcept C95190672 @default.
• W3195953400 hasConceptScore W3195953400C118552586 @default.
• W3195953400 hasConceptScore W3195953400C126322002 @default.
• W3195953400 hasConceptScore W3195953400C142724271 @default.
• W3195953400 hasConceptScore W3195953400C168563851 @default.
• W3195953400 hasConceptScore W3195953400C185592680 @default.
• W3195953400 hasConceptScore W3195953400C197934379 @default.
• W3195953400 hasConceptScore W3195953400C204787440 @default.
• W3195953400 hasConceptScore W3195953400C27081682 @default.
• W3195953400 hasConceptScore W3195953400C2776901510 @default.
• W3195953400 hasConceptScore W3195953400C2779753318 @default.
• W3195953400 hasConceptScore W3195953400C2780873584 @default.
• W3195953400 hasConceptScore W3195953400C2781066024 @default.

• next