FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3195986069> ?p ?o ?g. }

• W3195986069 endingPage "245" @default.
• W3195986069 startingPage "239" @default.
• W3195986069 abstract "Gemini surfactant nanocurcumin (Gemini-Cur) is a novel formulation of Curcumin (Cur) with dramatic suppressive effects on cancer cells. Here, we investigated the cancer effects of Gemini-Cur in a human gastric adenocarcinoma cell-line (AGS) through the evaluation of the expression of long non-coding RNAs colon cancer-associated transcript-2 (CCAT2) and its downstream c-Myc as known oncogenic modulators of tumorigenesis.The AGS cells were treated with Gemini-Cur and pure Cur in a time- and dose-dependent manner. The toxicity of Gemini-Cur was studied using 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and scratch tests. Furthermore, real-time polymerase chain reaction and Western blotting techniques were employed to evaluate the expression of genes.Gemini-Cur significantly affected the viability of AGS cells in a dose- and time-dependent manner with inhibitory concentration 50 values of 59.32, 40.88, and 19.63 µM during 24, 48, and 72 h, respectively. Our findings showed that Gemini-Cur effectively decreased the expression levels of lnc-CCAT2 and c-Myc genes. Western blotting analysis also confirmed the down-regulation of c-Myc in treated samples compared to controls.Gemini-Cur attenuates the proliferation of AGS cells partly through modulation of the lncCCAT2-related pathway." @default.
• W3195986069 created "2021-08-30" @default.
• W3195986069 creator A5002283021 @default.
• W3195986069 creator A5009513742 @default.
• W3195986069 creator A5079200425 @default.
• W3195986069 creator A5086371778 @default.
• W3195986069 creator A5090863268 @default.
• W3195986069 date "2022-06-27" @default.
• W3195986069 modified "2023-09-26" @default.
• W3195986069 title "Gemini Curcumin Suppresses Gastric Cancer AGS Cell Proliferation Through Modulation of lncRNA" @default.
• W3195986069 cites W1918772430 @default.
• W3195986069 cites W1929087671 @default.
• W3195986069 cites W1969608503 @default.
• W3195986069 cites W1975770667 @default.
• W3195986069 cites W1981278926 @default.
• W3195986069 cites W1986731647 @default.
• W3195986069 cites W2003870059 @default.
• W3195986069 cites W2012447906 @default.
• W3195986069 cites W2027799031 @default.
• W3195986069 cites W2030971688 @default.
• W3195986069 cites W2033431239 @default.
• W3195986069 cites W2046701189 @default.
• W3195986069 cites W2058907296 @default.
• W3195986069 cites W2079635465 @default.
• W3195986069 cites W2091161969 @default.
• W3195986069 cites W2121348051 @default.
• W3195986069 cites W2137631271 @default.
• W3195986069 cites W2156484966 @default.
• W3195986069 cites W2164157942 @default.
• W3195986069 cites W2189254216 @default.
• W3195986069 cites W2263613603 @default.
• W3195986069 cites W2341769195 @default.
• W3195986069 cites W2418464201 @default.
• W3195986069 cites W2550284103 @default.
• W3195986069 cites W2562605236 @default.
• W3195986069 cites W2594360359 @default.
• W3195986069 cites W2789740093 @default.
• W3195986069 cites W2901337977 @default.
• W3195986069 cites W2917837889 @default.
• W3195986069 cites W2937072818 @default.
• W3195986069 cites W2946453299 @default.
• W3195986069 cites W2997024745 @default.
• W3195986069 cites W2999417355 @default.
• W3195986069 cites W2999982330 @default.
• W3195986069 cites W3119005666 @default.
• W3195986069 cites W3154375282 @default.
• W3195986069 cites W3164090328 @default.
• W3195986069 cites W4255815238 @default.
• W3195986069 doi "https://doi.org/10.4274/tjps.galenos.2021.03502" @default.
• W3195986069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35773976" @default.
• W3195986069 hasPublicationYear "2022" @default.
• W3195986069 type Work @default.
• W3195986069 sameAs 3195986069 @default.
• W3195986069 citedByCount "2" @default.
• W3195986069 countsByYear W31959860692022 @default.
• W3195986069 countsByYear W31959860692023 @default.
• W3195986069 crossrefType "journal-article" @default.
• W3195986069 hasAuthorship W3195986069A5002283021 @default.
• W3195986069 hasAuthorship W3195986069A5009513742 @default.
• W3195986069 hasAuthorship W3195986069A5079200425 @default.
• W3195986069 hasAuthorship W3195986069A5086371778 @default.
• W3195986069 hasAuthorship W3195986069A5090863268 @default.
• W3195986069 hasBestOaLocation W31959860691 @default.
• W3195986069 hasConcept C104317684 @default.
• W3195986069 hasConcept C121608353 @default.
• W3195986069 hasConcept C1491633281 @default.
• W3195986069 hasConcept C153911025 @default.
• W3195986069 hasConcept C185592680 @default.
• W3195986069 hasConcept C2778250585 @default.
• W3195986069 hasConcept C48023723 @default.
• W3195986069 hasConcept C502942594 @default.
• W3195986069 hasConcept C53227056 @default.
• W3195986069 hasConcept C54355233 @default.
• W3195986069 hasConcept C55493867 @default.
• W3195986069 hasConcept C555283112 @default.
• W3195986069 hasConcept C62112901 @default.
• W3195986069 hasConcept C85265743 @default.
• W3195986069 hasConcept C86803240 @default.
• W3195986069 hasConceptScore W3195986069C104317684 @default.
• W3195986069 hasConceptScore W3195986069C121608353 @default.
• W3195986069 hasConceptScore W3195986069C1491633281 @default.
• W3195986069 hasConceptScore W3195986069C153911025 @default.
• W3195986069 hasConceptScore W3195986069C185592680 @default.
• W3195986069 hasConceptScore W3195986069C2778250585 @default.
• W3195986069 hasConceptScore W3195986069C48023723 @default.
• W3195986069 hasConceptScore W3195986069C502942594 @default.
• W3195986069 hasConceptScore W3195986069C53227056 @default.
• W3195986069 hasConceptScore W3195986069C54355233 @default.
• W3195986069 hasConceptScore W3195986069C55493867 @default.
• W3195986069 hasConceptScore W3195986069C555283112 @default.
• W3195986069 hasConceptScore W3195986069C62112901 @default.
• W3195986069 hasConceptScore W3195986069C85265743 @default.
• W3195986069 hasConceptScore W3195986069C86803240 @default.
• W3195986069 hasIssue "3" @default.
• W3195986069 hasLocation W31959860691 @default.
• W3195986069 hasLocation W31959860692 @default.
• W3195986069 hasLocation W31959860693 @default.
• W3195986069 hasOpenAccess W3195986069 @default.

• next