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• W3196018754 abstract "Recent data suggests that African American men (AAM) with prostate cancer (PCa) exhibit genetic alterations in highly penetrant germline genes, as well as low penetrant single nucleotide polymorphisms. The importance of germline variants of uncertain significance (VUS) remain poorly elucidated and given the elevated rates of VUS in AAM compared to Caucasians with PCa, further studies are needed to facilitate potential reclassification of VUS. Ongoing efforts to include AAM in genomics research is of paramount importance in order to ensure applicability of discoveries across diverse populations and potentially reduce PCa disparities as we embark on the era of precision medicine." @default.
• W3196018754 created "2021-08-30" @default.
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• W3196018754 date "2022-05-01" @default.
• W3196018754 modified "2023-09-25" @default.
• W3196018754 title "Germline Mutations in African American Men With Prostate Cancer: Incidence, Implications and Diagnostic Disparities" @default.
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• W3196018754 doi "https://doi.org/10.1016/j.urology.2021.08.017" @default.
• W3196018754 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34453957" @default.
• W3196018754 hasPublicationYear "2022" @default.
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