FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3196200597> ?p ?o ?g. }

• W3196200597 endingPage "2136" @default.
• W3196200597 startingPage "2127" @default.
• W3196200597 abstract "Abstract Purpose There is limited information on treatment recommendations for glioblastoma patients with poor performance status. Here, we aim to evaluate the association of radiotherapy on survival in glioblastoma patients presenting with poor postoperative performance status in first-line setting. Methods We retrospectively analyzed data of 93 glioblastoma patients presenting with poor postoperative performance status (ECOG 2–4) at the University Hospital Zurich, Switzerland, in the years 2005–2019. A total of 43 patients received radiotherapy with or without systemic therapy in the first-line setting, whereas 50 patients received no additive local or systemic treatment after initial biopsy or resection. Overall survival was calculated from primary diagnosis and from the end of radiotherapy. In addition, factors influencing survival were analyzed. Results Median overall survival from primary diagnosis was 6.2 months in the radiotherapy group (95% CI 6.2–14.8 weeks, range 2–149 weeks) and 2.3 months in the group without additive treatment (95% CI 1.3–7.4 weeks, range 0–28 weeks) ( p < 0.001). This survival benefit was confirmed by landmark analyses. Factors associated with overall survival were extent of resection and administration of radiotherapy with or without systemic treatment. Median survival from end of radiotherapy was 3 months (95% CI 4.3–21.7 weeks, range 0–72 weeks), with 25.6% ( n = 11) early termination of treatment and 83.7% ( n = 36) requiring radiotherapy as in-patients. Performance status improved in 27.9% ( n = 12) of patients after radiotherapy. Conclusion In this retrospective single-institution analysis, radiotherapy improved overall survival in patients with poor performance status, especially in patients who were amendable to neurosurgical resection." @default.
• W3196200597 created "2021-08-30" @default.
• W3196200597 creator A5017177249 @default.
• W3196200597 creator A5023510680 @default.
• W3196200597 creator A5025202387 @default.
• W3196200597 creator A5029096168 @default.
• W3196200597 creator A5039675644 @default.
• W3196200597 creator A5055289994 @default.
• W3196200597 creator A5075679674 @default.
• W3196200597 date "2021-08-26" @default.
• W3196200597 modified "2023-10-14" @default.
• W3196200597 title "Radiotherapy for glioblastoma patients with poor performance status" @default.
• W3196200597 cites W1573246910 @default.
• W3196200597 cites W1968985320 @default.
• W3196200597 cites W1970075720 @default.
• W3196200597 cites W1987327518 @default.
• W3196200597 cites W1994497191 @default.
• W3196200597 cites W2001660159 @default.
• W3196200597 cites W2004874843 @default.
• W3196200597 cites W2007678878 @default.
• W3196200597 cites W2048458879 @default.
• W3196200597 cites W2075528869 @default.
• W3196200597 cites W2096049398 @default.
• W3196200597 cites W2096287682 @default.
• W3196200597 cites W2107731988 @default.
• W3196200597 cites W2133611748 @default.
• W3196200597 cites W2135396269 @default.
• W3196200597 cites W2154526619 @default.
• W3196200597 cites W2161524493 @default.
• W3196200597 cites W2162605078 @default.
• W3196200597 cites W2168500356 @default.
• W3196200597 cites W2468136639 @default.
• W3196200597 cites W2599173434 @default.
• W3196200597 cites W2599750069 @default.
• W3196200597 cites W2600112631 @default.
• W3196200597 cites W2610403529 @default.
• W3196200597 cites W2952870574 @default.
• W3196200597 cites W2953554374 @default.
• W3196200597 cites W3020099303 @default.
• W3196200597 cites W3101069487 @default.
• W3196200597 cites W3110787789 @default.
• W3196200597 doi "https://doi.org/10.1007/s00432-021-03770-9" @default.
• W3196200597 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34448057" @default.
• W3196200597 hasPublicationYear "2021" @default.
• W3196200597 type Work @default.
• W3196200597 sameAs 3196200597 @default.
• W3196200597 citedByCount "2" @default.
• W3196200597 countsByYear W31962005972021 @default.
• W3196200597 countsByYear W31962005972023 @default.
• W3196200597 crossrefType "journal-article" @default.
• W3196200597 hasAuthorship W3196200597A5017177249 @default.
• W3196200597 hasAuthorship W3196200597A5023510680 @default.
• W3196200597 hasAuthorship W3196200597A5025202387 @default.
• W3196200597 hasAuthorship W3196200597A5029096168 @default.
• W3196200597 hasAuthorship W3196200597A5039675644 @default.
• W3196200597 hasAuthorship W3196200597A5055289994 @default.
• W3196200597 hasAuthorship W3196200597A5075679674 @default.
• W3196200597 hasBestOaLocation W31962005971 @default.
• W3196200597 hasConcept C126322002 @default.
• W3196200597 hasConcept C141071460 @default.
• W3196200597 hasConcept C167135981 @default.
• W3196200597 hasConcept C194409129 @default.
• W3196200597 hasConcept C2776194525 @default.
• W3196200597 hasConcept C2776907518 @default.
• W3196200597 hasConcept C3019894029 @default.
• W3196200597 hasConcept C502942594 @default.
• W3196200597 hasConcept C509974204 @default.
• W3196200597 hasConcept C71924100 @default.
• W3196200597 hasConceptScore W3196200597C126322002 @default.
• W3196200597 hasConceptScore W3196200597C141071460 @default.
• W3196200597 hasConceptScore W3196200597C167135981 @default.
• W3196200597 hasConceptScore W3196200597C194409129 @default.
• W3196200597 hasConceptScore W3196200597C2776194525 @default.
• W3196200597 hasConceptScore W3196200597C2776907518 @default.
• W3196200597 hasConceptScore W3196200597C3019894029 @default.
• W3196200597 hasConceptScore W3196200597C502942594 @default.
• W3196200597 hasConceptScore W3196200597C509974204 @default.
• W3196200597 hasConceptScore W3196200597C71924100 @default.
• W3196200597 hasFunder F4320323874 @default.
• W3196200597 hasIssue "8" @default.
• W3196200597 hasLocation W31962005971 @default.
• W3196200597 hasLocation W31962005972 @default.
• W3196200597 hasLocation W31962005973 @default.
• W3196200597 hasLocation W31962005974 @default.
• W3196200597 hasOpenAccess W3196200597 @default.
• W3196200597 hasPrimaryLocation W31962005971 @default.
• W3196200597 hasRelatedWork W1964832149 @default.
• W3196200597 hasRelatedWork W2131765892 @default.
• W3196200597 hasRelatedWork W2156925988 @default.
• W3196200597 hasRelatedWork W2216144508 @default.
• W3196200597 hasRelatedWork W2412894126 @default.
• W3196200597 hasRelatedWork W2463067288 @default.
• W3196200597 hasRelatedWork W2606371609 @default.
• W3196200597 hasRelatedWork W2963513685 @default.
• W3196200597 hasRelatedWork W3097948456 @default.
• W3196200597 hasRelatedWork W3118601174 @default.
• W3196200597 hasVolume "148" @default.
• W3196200597 isParatext "false" @default.

• next