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- W3196362076 abstract "Methicillin-resistant Staphylococcus aureus (MRSA) has become a major problem in the hospital as well as in the community setting. The resistance of MRSA to all β-lactam antibiotics and the most commonly prescribed group of antimicrobials for staphylococcal infections poses a significant limitation to the treatment of diseases caused by this multiple drug resistant strain. The study determined the antibacterial activity of some commercial disinfectants against methicillin-resistant Staphylococcus aureus (MRSA) isolates obtained from man and animal sources. A total of six disinfectants namely; Isol, Dettol, Roberts, Purit, Savlon, and Z-germicide were used for this study. The disinfectants were tested for antibacterial activity using agar well diffusion method. Maximum Inhibitory Dilution (MID) was also done using agar dilution technique. The extinction time of the different disinfectants used against the eight (8) MRSA isolates were determined by tube dilution method. The results revealed that the disinfectants had plausible inhibition zone diameters (IZD) ranging from 5 – 20 mm. The Maximum Inhibitory Dilution (MID) ranged from 1:125 – 1:500. The range of the Maximum Bactericidal Dilution (MBD) was from 1:62.5 – 1:500 and that of the extinction time was from 30 – 50 minutes. Isol had the highest activity even at lower concentrations when compared to the other disinfectants. There was a significant increase in the mean IZD of the disinfectants against the MRSA isolates. Thus, these disinfectants showed promising disinfecting properties and could be employed in the eradication of infections caused by MRSA pathogen." @default.
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- W3196362076 date "2013-01-01" @default.
- W3196362076 modified "2023-10-12" @default.
- W3196362076 title "Evaluation of the Antibacterial Activity of Some Commercial Disinfectants Against Methicillin- Resistant Staphylococcus Aureus" @default.
- W3196362076 doi "https://doi.org/10.2139/ssrn.3448993" @default.
- W3196362076 hasPublicationYear "2013" @default.
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