Matches in SemOpenAlex for { <https://semopenalex.org/work/W3196368732> ?p ?o ?g. }
- W3196368732 endingPage "585" @default.
- W3196368732 startingPage "575" @default.
- W3196368732 abstract "Recent computational fluid dynamics (CFD) studies have demonstrated the concurrence of atherosclerotic changes in regions exposed to prolonged blood residence. In this proof-of-concept study, we investigated a small but homogeneous cohort of large, cavernous carotid aneurysms (CCAs) to establish the clinical feasibility of CFD analysis in treatment planning, based on the association between pathophysiology and hemodynamics.This study included 15 patients with individual large CCAs. We identified calcifications, which indicated atherosclerotic changes, using the masking data of digital subtraction angiography. We conducted a CFD simulation under patient-specific inlet flow rates measured using magnetic resonance (MR) velocimetry. In the post-CFD analysis, we calculated the blood residence time ([Formula: see text]) and segmented the surface exposed to blood residence time over 1 s ([Formula: see text]). We measured the decrease in volume after flow diversion using the original time-of-flight MR angiography data.Calcifications were observed in the region with [Formula: see text]. In addition, the ratio of [Formula: see text] to the surface of the aneurysmal domain exhibited a negative relationship with the rate of volume reduction at the 6- and 12-month follow-ups. Post-CFD visualization demonstrated that intra-aneurysmal swirling flow prolonged blood residence time under the condition of a small inlet flow rate, when compared to the aneurysmal volume.The results of this study suggest the usefulness of CFD analysis for the diagnosis of atherosclerotic changes in large CCAs that may affect the therapeutic response after flow diversion." @default.
- W3196368732 created "2021-09-13" @default.
- W3196368732 creator A5014312128 @default.
- W3196368732 creator A5034738514 @default.
- W3196368732 creator A5038380698 @default.
- W3196368732 creator A5065317007 @default.
- W3196368732 creator A5074615107 @default.
- W3196368732 creator A5081069893 @default.
- W3196368732 creator A5090356821 @default.
- W3196368732 creator A5091559962 @default.
- W3196368732 date "2021-09-09" @default.
- W3196368732 modified "2023-10-18" @default.
- W3196368732 title "Prediction of atherosclerotic changes in cavernous carotid aneurysms based on computational fluid dynamics analysis: a proof-of-concept study" @default.
- W3196368732 cites W1735402834 @default.
- W3196368732 cites W1964112604 @default.
- W3196368732 cites W1984418657 @default.
- W3196368732 cites W1986618096 @default.
- W3196368732 cites W1996498223 @default.
- W3196368732 cites W1997704619 @default.
- W3196368732 cites W1998704545 @default.
- W3196368732 cites W2009656044 @default.
- W3196368732 cites W2021731311 @default.
- W3196368732 cites W2050517505 @default.
- W3196368732 cites W2050970791 @default.
- W3196368732 cites W2061215941 @default.
- W3196368732 cites W2066727422 @default.
- W3196368732 cites W2084621368 @default.
- W3196368732 cites W2100896768 @default.
- W3196368732 cites W2101569050 @default.
- W3196368732 cites W2105872075 @default.
- W3196368732 cites W2118220877 @default.
- W3196368732 cites W2121960517 @default.
- W3196368732 cites W2122601550 @default.
- W3196368732 cites W2142451194 @default.
- W3196368732 cites W2150027450 @default.
- W3196368732 cites W2164036220 @default.
- W3196368732 cites W2170152206 @default.
- W3196368732 cites W2334158209 @default.
- W3196368732 cites W2461227813 @default.
- W3196368732 cites W2518945321 @default.
- W3196368732 cites W2523954809 @default.
- W3196368732 cites W2783941418 @default.
- W3196368732 cites W2795702490 @default.
- W3196368732 cites W2895563532 @default.
- W3196368732 cites W2912358296 @default.
- W3196368732 cites W2913437262 @default.
- W3196368732 cites W2917541787 @default.
- W3196368732 cites W2941985417 @default.
- W3196368732 cites W2951926042 @default.
- W3196368732 cites W2955521236 @default.
- W3196368732 cites W2971160620 @default.
- W3196368732 cites W2994778844 @default.
- W3196368732 cites W3046016071 @default.
- W3196368732 cites W3106505983 @default.
- W3196368732 doi "https://doi.org/10.1007/s00234-021-02803-x" @default.
- W3196368732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34505180" @default.
- W3196368732 hasPublicationYear "2021" @default.
- W3196368732 type Work @default.
- W3196368732 sameAs 3196368732 @default.
- W3196368732 citedByCount "1" @default.
- W3196368732 countsByYear W31963687322022 @default.
- W3196368732 crossrefType "journal-article" @default.
- W3196368732 hasAuthorship W3196368732A5014312128 @default.
- W3196368732 hasAuthorship W3196368732A5034738514 @default.
- W3196368732 hasAuthorship W3196368732A5038380698 @default.
- W3196368732 hasAuthorship W3196368732A5065317007 @default.
- W3196368732 hasAuthorship W3196368732A5074615107 @default.
- W3196368732 hasAuthorship W3196368732A5081069893 @default.
- W3196368732 hasAuthorship W3196368732A5090356821 @default.
- W3196368732 hasAuthorship W3196368732A5091559962 @default.
- W3196368732 hasBestOaLocation W31963687322 @default.
- W3196368732 hasConcept C118552586 @default.
- W3196368732 hasConcept C121332964 @default.
- W3196368732 hasConcept C126322002 @default.
- W3196368732 hasConcept C126838900 @default.
- W3196368732 hasConcept C127313418 @default.
- W3196368732 hasConcept C143409427 @default.
- W3196368732 hasConcept C158846371 @default.
- W3196368732 hasConcept C1633027 @default.
- W3196368732 hasConcept C164705383 @default.
- W3196368732 hasConcept C16568411 @default.
- W3196368732 hasConcept C187320778 @default.
- W3196368732 hasConcept C2775913793 @default.
- W3196368732 hasConcept C2778212899 @default.
- W3196368732 hasConcept C2779889316 @default.
- W3196368732 hasConcept C57879066 @default.
- W3196368732 hasConcept C71924100 @default.
- W3196368732 hasConceptScore W3196368732C118552586 @default.
- W3196368732 hasConceptScore W3196368732C121332964 @default.
- W3196368732 hasConceptScore W3196368732C126322002 @default.
- W3196368732 hasConceptScore W3196368732C126838900 @default.
- W3196368732 hasConceptScore W3196368732C127313418 @default.
- W3196368732 hasConceptScore W3196368732C143409427 @default.
- W3196368732 hasConceptScore W3196368732C158846371 @default.
- W3196368732 hasConceptScore W3196368732C1633027 @default.
- W3196368732 hasConceptScore W3196368732C164705383 @default.
- W3196368732 hasConceptScore W3196368732C16568411 @default.
- W3196368732 hasConceptScore W3196368732C187320778 @default.