FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3196395067> ?p ?o ?g. }

• W3196395067 endingPage "n2182" @default.
• W3196395067 startingPage "n2182" @default.
• W3196395067 abstract "To assess the risks of developing dementia associated with different types and durations of menopausal hormone therapy.Two nested case-control studies.UK general practices contributing to QResearch or the Clinical Practice Research Datalink (CPRD), using all links to hospital, mortality, and social deprivation data.118 501 women aged 55 and older with a primary diagnosis of dementia between 1998 and 2020, matched by age, general practice, and index date to 497 416 female controls.Dementia diagnoses from general practice, mortality, and hospital records; odds ratios for menopausal hormone treatments adjusted for demographics, smoking status, alcohol consumption, comorbidities, family history, and other prescribed drugs.Overall, 16 291 (14%) women with a diagnosis of dementia and 68 726 (14%) controls had used menopausal hormone therapy more than three years before the index date. Overall, no increased risks of developing dementia associated with menopausal hormone therapy were observed. A decreased global risk of dementia was found among cases and controls younger than 80 years who had been taking oestrogen-only therapy for 10 years or more (adjusted odds ratio 0.85, 95% confidence interval 0.76 to 0.94). Increased risks of developing specifically Alzheimer's disease were found among women who had used oestrogen-progestogen therapy for between five and nine years (1.11, 1.04 to 1.20) and for 10 years or more (1.19, 1.06 to 1.33). This was equivalent to, respectively, five and seven extra cases per 10 000 woman years. Detailed risk associations for the specific progestogens studied are also provided.This study gives estimates for risks of developing dementia and Alzheimer's disease in women exposed to different types of menopausal hormone therapy for different durations and has shown no increased risks of developing dementia overall. It has shown a slightly increased risk of developing Alzheimer's disease among long term users of oestrogen-progestogen therapies." @default.
• W3196395067 created "2021-09-13" @default.
• W3196395067 creator A5004448187 @default.
• W3196395067 creator A5024344236 @default.
• W3196395067 creator A5026930128 @default.
• W3196395067 creator A5038600511 @default.
• W3196395067 creator A5078701828 @default.
• W3196395067 creator A5088025055 @default.
• W3196395067 date "2021-09-29" @default.
• W3196395067 modified "2023-10-09" @default.
• W3196395067 title "Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases" @default.
• W3196395067 cites W1006899190 @default.
• W3196395067 cites W1913092771 @default.
• W3196395067 cites W1976892327 @default.
• W3196395067 cites W1995405631 @default.
• W3196395067 cites W2033209427 @default.
• W3196395067 cites W2105087430 @default.
• W3196395067 cites W2109887283 @default.
• W3196395067 cites W2131266318 @default.
• W3196395067 cites W2161375627 @default.
• W3196395067 cites W2161695527 @default.
• W3196395067 cites W2465155672 @default.
• W3196395067 cites W2570136411 @default.
• W3196395067 cites W2736307756 @default.
• W3196395067 cites W2777443892 @default.
• W3196395067 cites W2909075990 @default.
• W3196395067 cites W2918710227 @default.
• W3196395067 cites W2980142131 @default.
• W3196395067 cites W3011020391 @default.
• W3196395067 cites W3097702496 @default.
• W3196395067 cites W4248217291 @default.
• W3196395067 doi "https://doi.org/10.1136/bmj.n2182" @default.
• W3196395067 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8479814" @default.
• W3196395067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34588168" @default.
• W3196395067 hasPublicationYear "2021" @default.
• W3196395067 type Work @default.
• W3196395067 sameAs 3196395067 @default.
• W3196395067 citedByCount "29" @default.
• W3196395067 countsByYear W31963950672021 @default.
• W3196395067 countsByYear W31963950672022 @default.
• W3196395067 countsByYear W31963950672023 @default.
• W3196395067 crossrefType "journal-article" @default.
• W3196395067 hasAuthorship W3196395067A5004448187 @default.
• W3196395067 hasAuthorship W3196395067A5024344236 @default.
• W3196395067 hasAuthorship W3196395067A5026930128 @default.
• W3196395067 hasAuthorship W3196395067A5038600511 @default.
• W3196395067 hasAuthorship W3196395067A5078701828 @default.
• W3196395067 hasAuthorship W3196395067A5088025055 @default.
• W3196395067 hasBestOaLocation W31963950671 @default.
• W3196395067 hasConcept C121608353 @default.
• W3196395067 hasConcept C126322002 @default.
• W3196395067 hasConcept C156957248 @default.
• W3196395067 hasConcept C165617652 @default.
• W3196395067 hasConcept C187212893 @default.
• W3196395067 hasConcept C2779134260 @default.
• W3196395067 hasConcept C2779279991 @default.
• W3196395067 hasConcept C2779483572 @default.
• W3196395067 hasConcept C2780159708 @default.
• W3196395067 hasConcept C2780275930 @default.
• W3196395067 hasConcept C41008148 @default.
• W3196395067 hasConcept C44249647 @default.
• W3196395067 hasConcept C530470458 @default.
• W3196395067 hasConcept C71924100 @default.
• W3196395067 hasConcept C77088390 @default.
• W3196395067 hasConceptScore W3196395067C121608353 @default.
• W3196395067 hasConceptScore W3196395067C126322002 @default.
• W3196395067 hasConceptScore W3196395067C156957248 @default.
• W3196395067 hasConceptScore W3196395067C165617652 @default.
• W3196395067 hasConceptScore W3196395067C187212893 @default.
• W3196395067 hasConceptScore W3196395067C2779134260 @default.
• W3196395067 hasConceptScore W3196395067C2779279991 @default.
• W3196395067 hasConceptScore W3196395067C2779483572 @default.
• W3196395067 hasConceptScore W3196395067C2780159708 @default.
• W3196395067 hasConceptScore W3196395067C2780275930 @default.
• W3196395067 hasConceptScore W3196395067C41008148 @default.
• W3196395067 hasConceptScore W3196395067C44249647 @default.
• W3196395067 hasConceptScore W3196395067C530470458 @default.
• W3196395067 hasConceptScore W3196395067C71924100 @default.
• W3196395067 hasConceptScore W3196395067C77088390 @default.
• W3196395067 hasLocation W31963950671 @default.
• W3196395067 hasLocation W31963950672 @default.
• W3196395067 hasLocation W31963950673 @default.
• W3196395067 hasLocation W31963950674 @default.
• W3196395067 hasLocation W31963950675 @default.
• W3196395067 hasLocation W31963950676 @default.
• W3196395067 hasLocation W31963950677 @default.
• W3196395067 hasOpenAccess W3196395067 @default.
• W3196395067 hasPrimaryLocation W31963950671 @default.
• W3196395067 hasRelatedWork W2001641834 @default.
• W3196395067 hasRelatedWork W2061782637 @default.
• W3196395067 hasRelatedWork W2140716683 @default.
• W3196395067 hasRelatedWork W2168593006 @default.
• W3196395067 hasRelatedWork W2517587727 @default.
• W3196395067 hasRelatedWork W2560379788 @default.
• W3196395067 hasRelatedWork W2909075990 @default.
• W3196395067 hasRelatedWork W2980856496 @default.
• W3196395067 hasRelatedWork W3196395067 @default.
• W3196395067 hasRelatedWork W1500926721 @default.

• next