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- W3196406821 abstract "Latin American geneticists have been contributing to the scientific development of Human and Medical Genetics fields since the early 1950s. In the last decades, as Medical Genetics is moving toward a new era of innovative therapies for previously untreatable conditions, the participation of Latin America in clinical trials is also increasing. This review discusses the particularities regarding funding, regulatory, and ethical aspects of conducting clinical trials for genetic diseases in Latin America, with an especial focus on Brazil, the largest country with the highest number of studies. Although there are still several barriers to overcome, the recent development of orphan drug legislation and policies for rare diseases in many Latin American countries indicates a growing opportunity for the participation of the region in international efforts for the development of new therapies for genetic diseases." @default.
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- W3196406821 date "2021-09-01" @default.
- W3196406821 modified "2023-10-17" @default.
- W3196406821 title "Clinical trials for genetic diseases in Latin America" @default.
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- W3196406821 doi "https://doi.org/10.1002/ajmg.c.31934" @default.
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