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- W3196715547 abstract "Viral infections are a major cause of morbidity and mortality in patients undergoing solid organ or hematopoietic stem cell transplantation. Due to their immunocompromised status, transplant recipients are at a higher risk for community-acquired and reactivated viral infections. Serologic screening prior to transplantation can assist with risk stratification of patients and guide decisions regarding the use of pre-emptive antiviral therapy. Following transplantation, molecular testing has become the most common method to detect viral infections, with histopathology of infected tissue often being required to confirm a diagnosis. Quantitative nucleic acid amplification tests have been the standard to detect and monitor viral infections in transplant patients; however, important challenges remain, including lack of standardization across many testing laboratories, limited availability of FDA-approved viral load assays, and the absence of universal viral load thresholds that can be used to diagnose disease and guide management decisions." @default.
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- W3196715547 date "2021-09-01" @default.
- W3196715547 modified "2023-09-27" @default.
- W3196715547 title "Diagnosis and Monitoring of Viral Infections in the Transplant Population" @default.
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- W3196715547 doi "https://doi.org/10.1016/j.clinmicnews.2021.08.003" @default.
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