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• W3196721389 abstract "Although LBM is positively associated with health outcomes, studies assessing determinants for the accrual of ht-LBM, such as physical activity, are limited. This study aimed to assess ht-LBM levels in pediatric kidney transplant recipients and test its association with baseline and contemporaneous variables, including physical activity.A retrospective cross-sectional review was performed on 46 pediatric kidney transplant recipients, and a longitudinal review was performed on a subset of recipients with serial post-transplant (n = 21) and pre/post-transplant (n = 11) ht-LBM measurements. Ht-LBM measurements were obtained using DXA scans.This cohort was 16.0 (IQR 12.3, 17.7) years old, 56.5% male and 46 ± 45 months post-transplant with a mean ht-LBM of 15.1 ± 2.5 kg/m2 . A median ht-LBM increase of 1.6 kg/m2 (IQR - 0.1, 2.6 kg/m2 ; p < .01) was observed, over 29.2 ± 12.0 months from the earliest post-transplant scan obtained at 46 ± 25 months post-transplant until the most recent post-transplant scan. A 1.7 ± 1.4 kg/m2 (p < .01) increase was observed between pre- and post-transplant DXA scans which were taken at 12 ± 11 months pre-transplant and 13 ± 6 months post-transplant, respectively. In separate adjusted models, lower physical activity questionnaire scores (n = 17, beta = 1.55, p = .02), faster rate of estimated glomerular filtration rate decline (beta = 0.05, p < .048) adjusted for annualized change in BSA, and younger age at scan (beta = 0.32, p < .01) were each significant predictors of lower ht-LBM.Physical activity and kidney function may influence ht-LBM in the pediatric kidney transplant population." @default.
• W3196721389 created "2021-09-13" @default.
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• W3196721389 date "2021-09-05" @default.
• W3196721389 modified "2023-09-25" @default.
• W3196721389 title "Height‐adjusted lean body mass and its associations with physical activity and kidney function in pediatric kidney transplantation" @default.
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• W3196721389 doi "https://doi.org/10.1111/petr.14128" @default.
• W3196721389 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34486205" @default.
• W3196721389 hasPublicationYear "2021" @default.
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