FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3196766487> ?p ?o ?g. }

• W3196766487 endingPage "C845" @default.
• W3196766487 startingPage "C826" @default.
• W3196766487 abstract "Thrombospondins (TSPs) are multidomain, secreted proteins that associate with cell surfaces and extracellular matrix. In mammals, there is a large body of data on functional roles of various TSP family members in cardiovascular disease (CVD), including stroke, cardiac remodeling and fibrosis, atherosclerosis, and aortic aneurysms. Coding single nucleotide polymorphisms (SNPs) of TSP1 or TSP4 are also associated with increased risk of several forms of CVD. Whereas interactions and functional effects of TSPs on a variety of cell types have been studied extensively, the molecular and cellular basis for the differential effects of the SNPs remains under investigation. Here, we provide an integrative review on TSPs, their roles in CVD and cardiovascular cell physiology, and known properties and mechanisms of TSP SNPs relevant to CVD. In considering recent expansions to knowledge of the fundamental cellular roles and mechanisms of TSPs, as well as the effects of wild-type and variant TSPs on cells of the cardiovascular system, we aim to highlight knowledge gaps and areas for future research or of translational potential." @default.
• W3196766487 created "2021-09-13" @default.
• W3196766487 creator A5019400296 @default.
• W3196766487 creator A5082494524 @default.
• W3196766487 creator A5085026769 @default.
• W3196766487 date "2021-11-01" @default.
• W3196766487 modified "2023-10-14" @default.
• W3196766487 title "In the balance: how do thrombospondins contribute to the cellular pathophysiology of cardiovascular disease?" @default.
• W3196766487 cites W1157846007 @default.
• W3196766487 cites W1505957065 @default.
• W3196766487 cites W1540929573 @default.
• W3196766487 cites W1545149841 @default.
• W3196766487 cites W1554302589 @default.
• W3196766487 cites W1605022460 @default.
• W3196766487 cites W1641418850 @default.
• W3196766487 cites W1691303215 @default.
• W3196766487 cites W1918712426 @default.
• W3196766487 cites W1928207529 @default.
• W3196766487 cites W1941829554 @default.
• W3196766487 cites W1961509164 @default.
• W3196766487 cites W1965293055 @default.
• W3196766487 cites W1969936268 @default.
• W3196766487 cites W1969937534 @default.
• W3196766487 cites W1970564104 @default.
• W3196766487 cites W1973967232 @default.
• W3196766487 cites W1976748977 @default.
• W3196766487 cites W1978202313 @default.
• W3196766487 cites W1979762232 @default.
• W3196766487 cites W1983348917 @default.
• W3196766487 cites W1988452935 @default.
• W3196766487 cites W1989471872 @default.
• W3196766487 cites W1993880593 @default.
• W3196766487 cites W1994293070 @default.
• W3196766487 cites W1996406153 @default.
• W3196766487 cites W1997254651 @default.
• W3196766487 cites W1998191794 @default.
• W3196766487 cites W1998225655 @default.
• W3196766487 cites W1999980010 @default.
• W3196766487 cites W2001384599 @default.
• W3196766487 cites W2003552873 @default.
• W3196766487 cites W2004128109 @default.
• W3196766487 cites W2010157566 @default.
• W3196766487 cites W2012034410 @default.
• W3196766487 cites W2012060788 @default.
• W3196766487 cites W2014216780 @default.
• W3196766487 cites W2015192667 @default.
• W3196766487 cites W2017132462 @default.
• W3196766487 cites W2017229503 @default.
• W3196766487 cites W2018625409 @default.
• W3196766487 cites W2019544080 @default.
• W3196766487 cites W2022149149 @default.
• W3196766487 cites W2022489052 @default.
• W3196766487 cites W2024158583 @default.
• W3196766487 cites W2027400904 @default.
• W3196766487 cites W2033486658 @default.
• W3196766487 cites W2036432791 @default.
• W3196766487 cites W2036470655 @default.
• W3196766487 cites W2037627915 @default.
• W3196766487 cites W2038048357 @default.
• W3196766487 cites W2039898357 @default.
• W3196766487 cites W2041234671 @default.
• W3196766487 cites W2041473277 @default.
• W3196766487 cites W2045782380 @default.
• W3196766487 cites W2055515174 @default.
• W3196766487 cites W2056795306 @default.
• W3196766487 cites W2057185663 @default.
• W3196766487 cites W2059600453 @default.
• W3196766487 cites W2063750068 @default.
• W3196766487 cites W2066143342 @default.
• W3196766487 cites W2066218332 @default.
• W3196766487 cites W2066948924 @default.
• W3196766487 cites W2068927254 @default.
• W3196766487 cites W2069012282 @default.
• W3196766487 cites W2069347028 @default.
• W3196766487 cites W2070050301 @default.
• W3196766487 cites W2072680312 @default.
• W3196766487 cites W2072890248 @default.
• W3196766487 cites W2073026500 @default.
• W3196766487 cites W2073439809 @default.
• W3196766487 cites W2075468691 @default.
• W3196766487 cites W2076618504 @default.
• W3196766487 cites W2077265886 @default.
• W3196766487 cites W2079426975 @default.
• W3196766487 cites W2080372048 @default.
• W3196766487 cites W2081058740 @default.
• W3196766487 cites W2084793796 @default.
• W3196766487 cites W2087636391 @default.
• W3196766487 cites W2089686007 @default.
• W3196766487 cites W2091293050 @default.
• W3196766487 cites W2096237827 @default.
• W3196766487 cites W2098622411 @default.
• W3196766487 cites W2100705421 @default.
• W3196766487 cites W2102034693 @default.
• W3196766487 cites W2104374650 @default.
• W3196766487 cites W2104661975 @default.
• W3196766487 cites W2105053181 @default.
• W3196766487 cites W2105614538 @default.
• W3196766487 cites W2109921861 @default.

• next