Matches in SemOpenAlex for { <https://semopenalex.org/work/W3196842902> ?p ?o ?g. }
- W3196842902 abstract "The incidence of renal cell carcinoma (RCC) is rising and metastatic RCC carries a very poor prognosis. The treatment paradigm for metastatic RCC has shifted dramatically in the last decade with multi-targeted tyrosine kinase inhibitors (TKI) previously used as first-line treatment but its utility is limited by short-lived efficacy and rapid disease progression. The dysregulation of immune cells in the tumour microenvironment contributes to unregulated growth of RCC. Thus, the use of immune checkpoint inhibitors has become first-line treatment for metastatic RCC and has offered dramatic improvement in clinical benefit and survival. Treatment with immune checkpoint inhibitor in combination with TKI appears to be promising in offering even greater response rates. The treatment for metastatic RCC continues to evolve and ongoing advances with new targeted agents and biomarkers are needed to continue to improve prognosis in the future." @default.
- W3196842902 created "2021-09-13" @default.
- W3196842902 creator A5030267291 @default.
- W3196842902 creator A5041594918 @default.
- W3196842902 date "2021-08-30" @default.
- W3196842902 modified "2023-10-18" @default.
- W3196842902 title "Immune Checkpoint Inhibitor in First-Line Treatment of Metastatic Renal Cell Carcinoma: A Review of Current Evidence and Future Directions" @default.
- W3196842902 cites W1544119899 @default.
- W3196842902 cites W1820627161 @default.
- W3196842902 cites W1999601075 @default.
- W3196842902 cites W2068081619 @default.
- W3196842902 cites W2073464835 @default.
- W3196842902 cites W2099752220 @default.
- W3196842902 cites W2129407204 @default.
- W3196842902 cites W2140010961 @default.
- W3196842902 cites W2140875987 @default.
- W3196842902 cites W2148706732 @default.
- W3196842902 cites W2149456801 @default.
- W3196842902 cites W2151293773 @default.
- W3196842902 cites W2170958767 @default.
- W3196842902 cites W2222086386 @default.
- W3196842902 cites W2461111111 @default.
- W3196842902 cites W2560219063 @default.
- W3196842902 cites W2726542547 @default.
- W3196842902 cites W2782183686 @default.
- W3196842902 cites W2783295481 @default.
- W3196842902 cites W2792937256 @default.
- W3196842902 cites W2799597692 @default.
- W3196842902 cites W2894313087 @default.
- W3196842902 cites W2896748530 @default.
- W3196842902 cites W2911812451 @default.
- W3196842902 cites W2913745075 @default.
- W3196842902 cites W2943887705 @default.
- W3196842902 cites W2949375297 @default.
- W3196842902 cites W2991986029 @default.
- W3196842902 cites W3018979351 @default.
- W3196842902 cites W3025451213 @default.
- W3196842902 cites W3032066384 @default.
- W3196842902 cites W3037914892 @default.
- W3196842902 cites W3089461485 @default.
- W3196842902 cites W3093923068 @default.
- W3196842902 cites W3107453141 @default.
- W3196842902 cites W3109157639 @default.
- W3196842902 cites W3118419510 @default.
- W3196842902 cites W3126738486 @default.
- W3196842902 cites W3131063362 @default.
- W3196842902 cites W3134803739 @default.
- W3196842902 cites W3134949580 @default.
- W3196842902 cites W3135754868 @default.
- W3196842902 cites W3135788188 @default.
- W3196842902 cites W3154810465 @default.
- W3196842902 doi "https://doi.org/10.3389/fonc.2021.707214" @default.
- W3196842902 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8435744" @default.
- W3196842902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34527581" @default.
- W3196842902 hasPublicationYear "2021" @default.
- W3196842902 type Work @default.
- W3196842902 sameAs 3196842902 @default.
- W3196842902 citedByCount "21" @default.
- W3196842902 countsByYear W31968429022021 @default.
- W3196842902 countsByYear W31968429022022 @default.
- W3196842902 countsByYear W31968429022023 @default.
- W3196842902 crossrefType "journal-article" @default.
- W3196842902 hasAuthorship W3196842902A5030267291 @default.
- W3196842902 hasAuthorship W3196842902A5041594918 @default.
- W3196842902 hasBestOaLocation W31968429021 @default.
- W3196842902 hasConcept C121608353 @default.
- W3196842902 hasConcept C126322002 @default.
- W3196842902 hasConcept C143998085 @default.
- W3196842902 hasConcept C203014093 @default.
- W3196842902 hasConcept C2776107976 @default.
- W3196842902 hasConcept C2777472916 @default.
- W3196842902 hasConcept C2777701055 @default.
- W3196842902 hasConcept C2778820342 @default.
- W3196842902 hasConcept C2780851360 @default.
- W3196842902 hasConcept C2781230642 @default.
- W3196842902 hasConcept C502942594 @default.
- W3196842902 hasConcept C71924100 @default.
- W3196842902 hasConcept C8891405 @default.
- W3196842902 hasConceptScore W3196842902C121608353 @default.
- W3196842902 hasConceptScore W3196842902C126322002 @default.
- W3196842902 hasConceptScore W3196842902C143998085 @default.
- W3196842902 hasConceptScore W3196842902C203014093 @default.
- W3196842902 hasConceptScore W3196842902C2776107976 @default.
- W3196842902 hasConceptScore W3196842902C2777472916 @default.
- W3196842902 hasConceptScore W3196842902C2777701055 @default.
- W3196842902 hasConceptScore W3196842902C2778820342 @default.
- W3196842902 hasConceptScore W3196842902C2780851360 @default.
- W3196842902 hasConceptScore W3196842902C2781230642 @default.
- W3196842902 hasConceptScore W3196842902C502942594 @default.
- W3196842902 hasConceptScore W3196842902C71924100 @default.
- W3196842902 hasConceptScore W3196842902C8891405 @default.
- W3196842902 hasLocation W31968429021 @default.
- W3196842902 hasLocation W31968429022 @default.
- W3196842902 hasLocation W31968429023 @default.
- W3196842902 hasOpenAccess W3196842902 @default.
- W3196842902 hasPrimaryLocation W31968429021 @default.
- W3196842902 hasRelatedWork W1755290823 @default.
- W3196842902 hasRelatedWork W2415433510 @default.
- W3196842902 hasRelatedWork W2563663251 @default.
- W3196842902 hasRelatedWork W3217412908 @default.