FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3196844528> ?p ?o ?g. }

• W3196844528 endingPage "114576" @default.
• W3196844528 startingPage "114576" @default.
• W3196844528 abstract "Pineapple (Ananas comosus) peel is a major waste in pineapple canning industry and it is reported to be used in ethnomedicine as a component of herbal remedies for malarial management. This study aimed to evaluate the antimalarial, antinociceptive and anti-inflammatory properties of Ananas comosus peel extract (PEAC).Ananas comosus peel was extracted with 80% methanol. PEAC (100, 200 and 400 mg/kg) was investigated for antimalarial effect using Peter's 4-day suppressive test (4-DST) model in mice. Antinociceptive activity of PEAC was investigated in hot plate, acetic acid-induced writhing and formalin tests in mice. The anti-inflammatory activity was evaluated using the lipopolysaccharides-induced sickness behavior in mice and carrageenan-induced air pouch in rats' models.PEAC could not significantly (p > 0.05) suppressed parasitemia level at 7-day post-infection in 4-DST. PEAC (400 mg/kg) mildly prolongs survival of infected mice up till day 21. PEAC demonstrated significant (p < 0.05) antinociceptive activity by increasing latency to jump on the hot plate, reduced number of writhings in acetic acid test and reduced paw licking time in 2nd phase of formalin test. PEAC significantly reduced anxiogenic and depressive-like symptoms of sickness behavior in LPS-injected mice. PEAC demonstrated significant anti-inflammatory activity in carrageenan-induced air pouch experiment by reducing exudates formation, inflammatory cell counts, and nitrite, tumor necrosis factor-alpha and interleukin-6 levels.Ananas comosus peel extract demonstrated mild antimalarial activity but significant anti-nociceptive and anti-inflammatory properties probably mediated via inhibition of pro-inflammatory mediators." @default.
• W3196844528 created "2021-09-13" @default.
• W3196844528 creator A5006603125 @default.
• W3196844528 creator A5011537139 @default.
• W3196844528 creator A5016865663 @default.
• W3196844528 creator A5053363634 @default.
• W3196844528 creator A5064124798 @default.
• W3196844528 date "2022-01-01" @default.
• W3196844528 modified "2023-10-01" @default.
• W3196844528 title "Ananas comosus (L) Merrill (pineapple) fruit peel extract demonstrates antimalarial, anti-nociceptive and anti-inflammatory activities in experimental models" @default.
• W3196844528 cites W1487878063 @default.
• W3196844528 cites W1506043065 @default.
• W3196844528 cites W1977429496 @default.
• W3196844528 cites W1983085370 @default.
• W3196844528 cites W1988573531 @default.
• W3196844528 cites W1993095775 @default.
• W3196844528 cites W1995556491 @default.
• W3196844528 cites W2021839965 @default.
• W3196844528 cites W2033634323 @default.
• W3196844528 cites W2038751434 @default.
• W3196844528 cites W2045313540 @default.
• W3196844528 cites W2045639540 @default.
• W3196844528 cites W2051690250 @default.
• W3196844528 cites W2056653713 @default.
• W3196844528 cites W2060058623 @default.
• W3196844528 cites W2073541816 @default.
• W3196844528 cites W2083932828 @default.
• W3196844528 cites W2087794389 @default.
• W3196844528 cites W2090657634 @default.
• W3196844528 cites W2096639957 @default.
• W3196844528 cites W2103752463 @default.
• W3196844528 cites W2109529422 @default.
• W3196844528 cites W2123289436 @default.
• W3196844528 cites W2124630308 @default.
• W3196844528 cites W2148172076 @default.
• W3196844528 cites W2162133004 @default.
• W3196844528 cites W2359932846 @default.
• W3196844528 cites W2601698371 @default.
• W3196844528 cites W2626657575 @default.
• W3196844528 cites W2789440701 @default.
• W3196844528 cites W2791016534 @default.
• W3196844528 cites W2802108898 @default.
• W3196844528 cites W2803592510 @default.
• W3196844528 cites W2888772515 @default.
• W3196844528 cites W2891046942 @default.
• W3196844528 cites W2899323224 @default.
• W3196844528 cites W2904216211 @default.
• W3196844528 cites W2968918584 @default.
• W3196844528 cites W3006631966 @default.
• W3196844528 cites W3014541504 @default.
• W3196844528 cites W3016210359 @default.
• W3196844528 cites W3016456286 @default.
• W3196844528 cites W3025368231 @default.
• W3196844528 cites W3025751058 @default.
• W3196844528 cites W3047728101 @default.
• W3196844528 cites W3080551778 @default.
• W3196844528 cites W3119892428 @default.
• W3196844528 cites W3169617373 @default.
• W3196844528 cites W4238419532 @default.
• W3196844528 cites W849426764 @default.
• W3196844528 cites W858975635 @default.
• W3196844528 doi "https://doi.org/10.1016/j.jep.2021.114576" @default.
• W3196844528 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34461191" @default.
• W3196844528 hasPublicationYear "2022" @default.
• W3196844528 type Work @default.
• W3196844528 sameAs 3196844528 @default.
• W3196844528 citedByCount "11" @default.
• W3196844528 countsByYear W31968445282021 @default.
• W3196844528 countsByYear W31968445282022 @default.
• W3196844528 countsByYear W31968445282023 @default.
• W3196844528 crossrefType "journal-article" @default.
• W3196844528 hasAuthorship W3196844528A5006603125 @default.
• W3196844528 hasAuthorship W3196844528A5011537139 @default.
• W3196844528 hasAuthorship W3196844528A5016865663 @default.
• W3196844528 hasAuthorship W3196844528A5053363634 @default.
• W3196844528 hasAuthorship W3196844528A5064124798 @default.
• W3196844528 hasConcept C15490471 @default.
• W3196844528 hasConcept C170493617 @default.
• W3196844528 hasConcept C185592680 @default.
• W3196844528 hasConcept C2776613168 @default.
• W3196844528 hasConcept C2779703632 @default.
• W3196844528 hasConcept C2780723003 @default.
• W3196844528 hasConcept C52396799 @default.
• W3196844528 hasConcept C55493867 @default.
• W3196844528 hasConcept C556039675 @default.
• W3196844528 hasConcept C59822182 @default.
• W3196844528 hasConcept C71924100 @default.
• W3196844528 hasConcept C86803240 @default.
• W3196844528 hasConcept C98274493 @default.
• W3196844528 hasConceptScore W3196844528C15490471 @default.
• W3196844528 hasConceptScore W3196844528C170493617 @default.
• W3196844528 hasConceptScore W3196844528C185592680 @default.
• W3196844528 hasConceptScore W3196844528C2776613168 @default.
• W3196844528 hasConceptScore W3196844528C2779703632 @default.
• W3196844528 hasConceptScore W3196844528C2780723003 @default.
• W3196844528 hasConceptScore W3196844528C52396799 @default.
• W3196844528 hasConceptScore W3196844528C55493867 @default.
• W3196844528 hasConceptScore W3196844528C556039675 @default.

• next