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- W3196992783 abstract "Cardiac arrhythmias are a leading cause of morbidity and mortality in the developed world. A common mechanism underlying many of these arrhythmias is re-entry, which may occur when native conduction pathways are disrupted, often by myocardial infarction. Presently, re-entrant arrhythmias are most commonly treated with antiarrhythmic drugs and myocardial ablation, although both treatment methods are associated with adverse side effects and limited efficacy. In recent years, significant advancements in the field of biomaterials science have spurred increased interest in the development of novel therapies that enable restoration of native conduction in damaged or diseased myocardium. In this review, we assess the current landscape of materials-based approaches to eliminating re-entrant arrhythmias. These approaches potentially pave the way for the eventual replacement of myocardial ablation as a preferred therapy for such pathologies." @default.
- W3196992783 created "2021-09-13" @default.
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- W3196992783 date "2021-09-03" @default.
- W3196992783 modified "2023-10-16" @default.
- W3196992783 title "Reconstituting electrical conduction in soft tissue: the path to replace the ablationist" @default.
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- W3196992783 doi "https://doi.org/10.1093/europace/euab187" @default.
- W3196992783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34477862" @default.
- W3196992783 hasPublicationYear "2021" @default.
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