Matches in SemOpenAlex for { <https://semopenalex.org/work/W3196994055> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W3196994055 endingPage "95" @default.
- W3196994055 startingPage "91" @default.
- W3196994055 abstract "Alzheimer’s disease (AD) which is usually referred to as Alzheimer’s is one of the popular reasons for dementia. Mg-Salvia Officinalis NPs has been known as an interesting compound with antioxidant, anti-inflammatory and cognitive properties. The possible therapeutic effect of Mg-Salvia Officinalis NPs was evaluated in Aluminum Chloride (ALCL3) induced AD. AD was induced by intraperitoneal injection of ALCL3 at a dose (100 mg/kg b. wt.) for 2 weeks. Fifty male rats were equally divided into 5 groups. Group I (Normal control): Rats received no drugs, Group II (ALCL3- induced AD): Rats injected with ALCL3 (100mg/kg b. wt./I. P) for two weeks, Group III (Mg-Salvia Officinalis NPs treated): After 14 days of ALCL3 injection, rats treated with Mg-Salvia Officinalis NPs (5mg/kg b. wt./day, orally) for four weeks. Group IV (Donepezil treated): Rats injected with ALCL3 as group II and treated with Donepezil (1mg/kg b. wt./day, orally) for four weeks. Group V (Mg-Salvia Officinalis NPs and Donepezil treated): Rats injected with ALCL3 and treated daily with Mg-Salvia Officinalis NPs and Donepezil for four weeks. The results revealed that ALCL3-induced AD rats causing significant alterations in Tau protein and acetylcholine levels in brain tissue in addition to marked elevation of serum ALT, AST activities, urea, creatinine concentrations and oxidative stress biomarkers. Treatment with Mg-Salvia Officinalis NPs to AD rats caused marked improvement effect in all previous parameters. Conclusively, Salvia Officinalis NPs treatment ameliorates oxidative stress induced by ALCL3 in rat’s model of AD and enhances antioxidant defense system, and prevent the lipid peroxidation." @default.
- W3196994055 created "2021-09-13" @default.
- W3196994055 creator A5002317577 @default.
- W3196994055 creator A5040822453 @default.
- W3196994055 creator A5046724854 @default.
- W3196994055 creator A5088896326 @default.
- W3196994055 date "2021-07-01" @default.
- W3196994055 modified "2023-10-17" @default.
- W3196994055 title "Ameliorative effect of Mg-Salvia Officinalis Nanoparticles against Aluminum Chloride induced oxidative stress in rat model of Alzheimer's Disease" @default.
- W3196994055 cites W1512742807 @default.
- W3196994055 cites W1970345407 @default.
- W3196994055 cites W1971048984 @default.
- W3196994055 cites W1978397325 @default.
- W3196994055 cites W1993851201 @default.
- W3196994055 cites W2002575458 @default.
- W3196994055 cites W2011114549 @default.
- W3196994055 cites W2050206187 @default.
- W3196994055 cites W2066115280 @default.
- W3196994055 cites W2068267549 @default.
- W3196994055 cites W2080075827 @default.
- W3196994055 cites W2101265858 @default.
- W3196994055 cites W2131819352 @default.
- W3196994055 cites W2134979720 @default.
- W3196994055 cites W2159776145 @default.
- W3196994055 cites W2263023695 @default.
- W3196994055 cites W2314461618 @default.
- W3196994055 cites W2553086500 @default.
- W3196994055 cites W2572208524 @default.
- W3196994055 cites W2621071497 @default.
- W3196994055 cites W2621126031 @default.
- W3196994055 cites W2776562011 @default.
- W3196994055 cites W2902513420 @default.
- W3196994055 cites W2916641566 @default.
- W3196994055 cites W2990102338 @default.
- W3196994055 cites W2998390528 @default.
- W3196994055 cites W3025288017 @default.
- W3196994055 cites W2341947314 @default.
- W3196994055 cites W2942911788 @default.
- W3196994055 doi "https://doi.org/10.21608/bvmj.2021.72222.1395" @default.
- W3196994055 hasPublicationYear "2021" @default.
- W3196994055 type Work @default.
- W3196994055 sameAs 3196994055 @default.
- W3196994055 citedByCount "1" @default.
- W3196994055 countsByYear W31969940552022 @default.
- W3196994055 crossrefType "journal-article" @default.
- W3196994055 hasAuthorship W3196994055A5002317577 @default.
- W3196994055 hasAuthorship W3196994055A5040822453 @default.
- W3196994055 hasAuthorship W3196994055A5046724854 @default.
- W3196994055 hasAuthorship W3196994055A5088896326 @default.
- W3196994055 hasBestOaLocation W31969940551 @default.
- W3196994055 hasConcept C126322002 @default.
- W3196994055 hasConcept C178790620 @default.
- W3196994055 hasConcept C185592680 @default.
- W3196994055 hasConcept C2776151105 @default.
- W3196994055 hasConcept C2776473397 @default.
- W3196994055 hasConcept C2778695967 @default.
- W3196994055 hasConcept C2779134260 @default.
- W3196994055 hasConcept C2780886089 @default.
- W3196994055 hasConcept C2911011617 @default.
- W3196994055 hasConcept C55493867 @default.
- W3196994055 hasConcept C556039675 @default.
- W3196994055 hasConcept C71924100 @default.
- W3196994055 hasConceptScore W3196994055C126322002 @default.
- W3196994055 hasConceptScore W3196994055C178790620 @default.
- W3196994055 hasConceptScore W3196994055C185592680 @default.
- W3196994055 hasConceptScore W3196994055C2776151105 @default.
- W3196994055 hasConceptScore W3196994055C2776473397 @default.
- W3196994055 hasConceptScore W3196994055C2778695967 @default.
- W3196994055 hasConceptScore W3196994055C2779134260 @default.
- W3196994055 hasConceptScore W3196994055C2780886089 @default.
- W3196994055 hasConceptScore W3196994055C2911011617 @default.
- W3196994055 hasConceptScore W3196994055C55493867 @default.
- W3196994055 hasConceptScore W3196994055C556039675 @default.
- W3196994055 hasConceptScore W3196994055C71924100 @default.
- W3196994055 hasIssue "2" @default.
- W3196994055 hasLocation W31969940551 @default.
- W3196994055 hasOpenAccess W3196994055 @default.
- W3196994055 hasPrimaryLocation W31969940551 @default.
- W3196994055 hasRelatedWork W1520714167 @default.
- W3196994055 hasRelatedWork W2000310053 @default.
- W3196994055 hasRelatedWork W2317827336 @default.
- W3196994055 hasRelatedWork W2508321288 @default.
- W3196994055 hasRelatedWork W2970947296 @default.
- W3196994055 hasRelatedWork W3119262044 @default.
- W3196994055 hasRelatedWork W3211772254 @default.
- W3196994055 hasRelatedWork W4242119498 @default.
- W3196994055 hasRelatedWork W4284702443 @default.
- W3196994055 hasRelatedWork W2183333603 @default.
- W3196994055 hasVolume "40" @default.
- W3196994055 isParatext "false" @default.
- W3196994055 isRetracted "false" @default.
- W3196994055 magId "3196994055" @default.
- W3196994055 workType "article" @default.