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- W3197013676 abstract "Clozapine is commonly prescribed in dopamine supersensitivity psychosis (DSP) cases in Japan. However, limited knowledge on treatment post-clozapine discontinuation use exists. We investigated antipsychotic medications, patient status, and DSP episodes before, during, and after clozapine treatment using medical records of 30 schizophrenia patients (mean age, 51 years; mean illness duration before clozapine treatment, 24 years; mean clozapine treatment duration, 1.6 years), who discontinued clozapine between 2009 and 2019. In our region, long-acting injectable antipsychotic monotherapy and polypharmacy (half with aripiprazole) accounted for 17% and 50% post-clozapine use, respectively. Furthermore, patient status rarely improved with subsequent DSP treatment, including clozapine re-initiation." @default.
- W3197013676 created "2021-09-13" @default.
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- W3197013676 date "2021-11-01" @default.
- W3197013676 modified "2023-09-25" @default.
- W3197013676 title "Post-clozapine in a clinical setting: A retrospective case note review in Kumamoto, Japan (2009–2019)" @default.
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- W3197013676 doi "https://doi.org/10.1016/j.ajp.2021.102845" @default.
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