FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3197149574> ?p ?o ?g. }

• W3197149574 endingPage "1715" @default.
• W3197149574 startingPage "1707" @default.
• W3197149574 abstract "COVID-19 causes a range of clinical symptoms from mild to critical and can be life-threatening. Up to now, it has led to many deaths. We aimed to evaluate exhausted markers on CD4+ T cells of COVID-19 patients.In this study, we evaluated 44 patients with confirmed COVID-19 disease and 16 healthy individuals. Patients were divided into moderate/severe and critical groups. Peripheral blood mononuclear cells (PBMCs) were isolated and stained by anti-human CD39, PD-1, TIM-3, and anti-human CD4. The percentage of each CD4+ subpopulation was calculated by flow cytometry. Furthermore, we collected clinical information and laboratory data of both control and patient groups.We detected overexpression of TIM-3 on CD4+ T cells in both critical and moderate/severe patients than in healthy individuals (HIs; p < .01 and p < .0001, respectively). CD4+ TIM-3+ CD39+ lymphocytes were significantly higher in the critical patients than in HI (p < .05). Both Patient groups showed lymphopenia in comparison with HI, but CD4+ lymphocytes did not show any significant difference between study subjects. The increased amount of C-reactive protein, erythrocyte sedimentation rate, creatinine, blood urea nitrogen, and neutrophil count was observed in patients compared to HI.T cell exhaustion occurs during COVID-19 disease and TIM-3 is the most important exhausted marker on CD4+ T cells." @default.
• W3197149574 created "2021-09-13" @default.
• W3197149574 creator A5008604176 @default.
• W3197149574 creator A5015044256 @default.
• W3197149574 creator A5028027632 @default.
• W3197149574 creator A5058658672 @default.
• W3197149574 creator A5085590538 @default.
• W3197149574 creator A5090675599 @default.
• W3197149574 date "2021-09-09" @default.
• W3197149574 modified "2023-09-30" @default.
• W3197149574 title "TIM‐3 as a potential exhaustion marker in CD4⁺ T cells of COVID‐19 patients" @default.
• W3197149574 cites W1540592014 @default.
• W3197149574 cites W1591146540 @default.
• W3197149574 cites W1994257755 @default.
• W3197149574 cites W2021379322 @default.
• W3197149574 cites W2057002646 @default.
• W3197149574 cites W2070631889 @default.
• W3197149574 cites W2119896120 @default.
• W3197149574 cites W2134122465 @default.
• W3197149574 cites W2137846184 @default.
• W3197149574 cites W2152014155 @default.
• W3197149574 cites W2168231169 @default.
• W3197149574 cites W2168489055 @default.
• W3197149574 cites W2170856427 @default.
• W3197149574 cites W2597787622 @default.
• W3197149574 cites W2792292919 @default.
• W3197149574 cites W2802665663 @default.
• W3197149574 cites W2909521584 @default.
• W3197149574 cites W2944266663 @default.
• W3197149574 cites W2981066100 @default.
• W3197149574 cites W2998394393 @default.
• W3197149574 cites W3001118548 @default.
• W3197149574 cites W3002108456 @default.
• W3197149574 cites W3006887831 @default.
• W3197149574 cites W3007940623 @default.
• W3197149574 cites W3009582878 @default.
• W3197149574 cites W3010223921 @default.
• W3197149574 cites W3015289726 @default.
• W3197149574 cites W3018517500 @default.
• W3197149574 cites W3018868982 @default.
• W3197149574 cites W3023991776 @default.
• W3197149574 cites W3024541652 @default.
• W3197149574 cites W3197149574 @default.
• W3197149574 cites W4205623043 @default.
• W3197149574 doi "https://doi.org/10.1002/iid3.526" @default.
• W3197149574 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8589347" @default.
• W3197149574 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34499819" @default.
• W3197149574 hasPublicationYear "2021" @default.
• W3197149574 type Work @default.
• W3197149574 sameAs 3197149574 @default.
• W3197149574 citedByCount "18" @default.
• W3197149574 countsByYear W31971495742021 @default.
• W3197149574 countsByYear W31971495742022 @default.
• W3197149574 countsByYear W31971495742023 @default.
• W3197149574 crossrefType "journal-article" @default.
• W3197149574 hasAuthorship W3197149574A5008604176 @default.
• W3197149574 hasAuthorship W3197149574A5015044256 @default.
• W3197149574 hasAuthorship W3197149574A5028027632 @default.
• W3197149574 hasAuthorship W3197149574A5058658672 @default.
• W3197149574 hasAuthorship W3197149574A5085590538 @default.
• W3197149574 hasAuthorship W3197149574A5090675599 @default.
• W3197149574 hasBestOaLocation W31971495741 @default.
• W3197149574 hasConcept C126322002 @default.
• W3197149574 hasConcept C137061746 @default.
• W3197149574 hasConcept C202751555 @default.
• W3197149574 hasConcept C203014093 @default.
• W3197149574 hasConcept C2778143017 @default.
• W3197149574 hasConcept C2779134260 @default.
• W3197149574 hasConcept C2780306776 @default.
• W3197149574 hasConcept C3008058167 @default.
• W3197149574 hasConcept C524204448 @default.
• W3197149574 hasConcept C553184892 @default.
• W3197149574 hasConcept C55493867 @default.
• W3197149574 hasConcept C71924100 @default.
• W3197149574 hasConcept C86803240 @default.
• W3197149574 hasConcept C90924648 @default.
• W3197149574 hasConceptScore W3197149574C126322002 @default.
• W3197149574 hasConceptScore W3197149574C137061746 @default.
• W3197149574 hasConceptScore W3197149574C202751555 @default.
• W3197149574 hasConceptScore W3197149574C203014093 @default.
• W3197149574 hasConceptScore W3197149574C2778143017 @default.
• W3197149574 hasConceptScore W3197149574C2779134260 @default.
• W3197149574 hasConceptScore W3197149574C2780306776 @default.
• W3197149574 hasConceptScore W3197149574C3008058167 @default.
• W3197149574 hasConceptScore W3197149574C524204448 @default.
• W3197149574 hasConceptScore W3197149574C553184892 @default.
• W3197149574 hasConceptScore W3197149574C55493867 @default.
• W3197149574 hasConceptScore W3197149574C71924100 @default.
• W3197149574 hasConceptScore W3197149574C86803240 @default.
• W3197149574 hasConceptScore W3197149574C90924648 @default.
• W3197149574 hasFunder F4320323386 @default.
• W3197149574 hasIssue "4" @default.
• W3197149574 hasLocation W31971495741 @default.
• W3197149574 hasLocation W31971495742 @default.
• W3197149574 hasLocation W31971495743 @default.
• W3197149574 hasLocation W31971495744 @default.
• W3197149574 hasOpenAccess W3197149574 @default.
• W3197149574 hasPrimaryLocation W31971495741 @default.

• next