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- W3197178843 startingPage "367" @default.
- W3197178843 abstract "The two major challenges in cancer treatment include lack of early detection and ineffective therapies with various side effects. Angiogenesis is the key process in the growth, survival, invasiveness, and metastasis of many of cancerous tumors. Imaging of the angiogenesis could lead to diagnosis of tumors in the early stage and evaluation of the therapeutic responses. Angiogenic blood vessels express specific molecular markers different from normal blood vessels (in level or kind). This fact would make the tumor vasculature a suitable site to target therapeutics and imaging agents within the tumor. Surface modified nanoparticles using peptide ligands with high binding affinity to the vasculature markers, provide efficient delivery of therapeutic and imaging agents, while avoiding undesirable side effects. In this review, we discuss discoveries of various tumor targeting peptides useful for tumor angiogenesis imaging and targeted therapy with emphasis on surface modified nanomedicines using vasculature targeting peptides." @default.
- W3197178843 created "2021-09-13" @default.
- W3197178843 creator A5003793995 @default.
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- W3197178843 creator A5037072764 @default.
- W3197178843 creator A5061890110 @default.
- W3197178843 creator A5076086753 @default.
- W3197178843 date "2021-10-01" @default.
- W3197178843 modified "2023-10-17" @default.
- W3197178843 title "Nanoparticles modified with vasculature-homing peptides for targeted cancer therapy and angiogenesis imaging" @default.
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