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• W3197219353 abstract "<h2>Abstract</h2> <b>Objective:</b> Trichinellosis is a globally distributed food-borne parasitic disease. Initially, diagnosis is usually made based on clinical signs, symptoms, and history of eating raw or undercooked meat. In the present study, an immunochromatographic test (ICT) kit was developed to diagnose trichinellosis by detecting IgG antibodies in sera of infected humans. <b>Methods:</b> Somatic extract from <i>Trichinella spiralis</i> larvae was used as the antigen for the ICT kit development. Diagnostic efficacy was evaluated using human serum samples from proven trichinellosis patients, healthy persons, and those with other parasitic infections. <b>Results:</b> The diagnostic sensitivity, specificity, positive and negative predictive values and accuracy of the ICT kit were 100.0% (95%; CI 88.8 to 100.0%), 92.5% (95% CI; 86.9 to 96.2%), 73.8% (95% CI; 58.0 to 86.1%), 100.0% (95% CI; 97.3 to 100.0%) and 93.8% (95% CI; 89.2 to 96.9%), respectively. <b>Conclusions:</b> This ICT diagnostic kit can be used as a testing tool for human trichinellosis. This test should permit rapid detection of infection to enable prompt anthelminthic treatment. It can also be used for retrospective diagnoses and field surveys based at laboratories where sophisticated equipment is lacking." @default.
• W3197219353 created "2021-09-13" @default.
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• W3197219353 date "2021-10-01" @default.
• W3197219353 modified "2023-09-23" @default.
• W3197219353 title "Development of an immunochromatographic point-of-care test for detection of IgG antibody in serodiagnosis of human trichinellosis" @default.
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• W3197219353 doi "https://doi.org/10.1016/j.ijid.2021.08.056" @default.
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