Matches in SemOpenAlex for { <https://semopenalex.org/work/W3197269436> ?p ?o ?g. }
- W3197269436 endingPage "618" @default.
- W3197269436 startingPage "608" @default.
- W3197269436 abstract "Ambient temperature considerably affects the physiology and behavior of mammals. Thermosensory and thermoregulatory abilities play an important role in the response to changing ambient temperature in endotherms. However, the molecular mechanisms of behavioral thermoregulation remain poorly understood. Transient receptor potential vanilloid-1 (TRPV1) is activated by changes in ambient temperature and is involved in acute thermoregulation. Here, we aimed to determine whether TRPV1 is involved in behavioral thermoregulation in wild rodents by conducting 2 experiments. In the first, 42 adult Mongolian gerbils (Meriones unguiculatus; 14 per treatment) were randomly assigned to 3 housing temperatures (4, 23, and 36°C) for 4 weeks. In the second, 20 gerbils (10 per treatment) were randomly injected with capsaicin (TRPV1 agonist) or AMG517 (TRPV1 antagonist). The results showed a significant decrease in food intake and non-shivering thermogenesis in the gerbils housed at 36°C. Additionally, there was a significant increase in the preference of gerbils housed at 4°C to low temperatures. The expression of TRPV1 protein in the brown adipose tissue (BAT) and liver was significantly positively correlated with that of protein kinase A (PKA). The expression of TRPV1 and PKA proteins in the BAT was positively correlated with the temperature preference of the gerbils. The gerbils injected with capsaicin preferred significantly lower temperatures than the control group gerbils. These findings suggest that TRPV1 and PKA are involved in behavioral thermoregulation in Mongolian gerbils." @default.
- W3197269436 created "2021-09-13" @default.
- W3197269436 creator A5007582637 @default.
- W3197269436 creator A5038860267 @default.
- W3197269436 creator A5071957113 @default.
- W3197269436 creator A5080907045 @default.
- W3197269436 date "2021-09-22" @default.
- W3197269436 modified "2023-10-16" @default.
- W3197269436 title "Role of transient receptor potential vanilloid‐1 in behavioral thermoregulation of the Mongolian gerbil <i>Meriones unguiculatus</i>" @default.
- W3197269436 cites W1511198581 @default.
- W3197269436 cites W1593680573 @default.
- W3197269436 cites W1890090833 @default.
- W3197269436 cites W1966893270 @default.
- W3197269436 cites W1979557993 @default.
- W3197269436 cites W1981524122 @default.
- W3197269436 cites W1982462791 @default.
- W3197269436 cites W1990482286 @default.
- W3197269436 cites W1994452982 @default.
- W3197269436 cites W1995464542 @default.
- W3197269436 cites W2005957251 @default.
- W3197269436 cites W2007034094 @default.
- W3197269436 cites W2018344760 @default.
- W3197269436 cites W2019850520 @default.
- W3197269436 cites W2023375761 @default.
- W3197269436 cites W2023966426 @default.
- W3197269436 cites W2026826694 @default.
- W3197269436 cites W2029448317 @default.
- W3197269436 cites W2034458389 @default.
- W3197269436 cites W2035526473 @default.
- W3197269436 cites W2042619723 @default.
- W3197269436 cites W2045017043 @default.
- W3197269436 cites W2050781058 @default.
- W3197269436 cites W2051794578 @default.
- W3197269436 cites W2055642679 @default.
- W3197269436 cites W2057471044 @default.
- W3197269436 cites W2065634669 @default.
- W3197269436 cites W2066046552 @default.
- W3197269436 cites W2073881065 @default.
- W3197269436 cites W2084958910 @default.
- W3197269436 cites W2110059036 @default.
- W3197269436 cites W2110886687 @default.
- W3197269436 cites W2119934340 @default.
- W3197269436 cites W2131238198 @default.
- W3197269436 cites W2157174760 @default.
- W3197269436 cites W2161965097 @default.
- W3197269436 cites W2324666677 @default.
- W3197269436 cites W2331762773 @default.
- W3197269436 cites W2354621795 @default.
- W3197269436 cites W2496096408 @default.
- W3197269436 cites W2735614921 @default.
- W3197269436 cites W2792236328 @default.
- W3197269436 cites W2806477286 @default.
- W3197269436 cites W2883542518 @default.
- W3197269436 cites W2904305999 @default.
- W3197269436 cites W2917618237 @default.
- W3197269436 cites W2938195239 @default.
- W3197269436 cites W3020298971 @default.
- W3197269436 doi "https://doi.org/10.1111/1749-4877.12587" @default.
- W3197269436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34498418" @default.
- W3197269436 hasPublicationYear "2021" @default.
- W3197269436 type Work @default.
- W3197269436 sameAs 3197269436 @default.
- W3197269436 citedByCount "4" @default.
- W3197269436 countsByYear W31972694362022 @default.
- W3197269436 countsByYear W31972694362023 @default.
- W3197269436 crossrefType "journal-article" @default.
- W3197269436 hasAuthorship W3197269436A5007582637 @default.
- W3197269436 hasAuthorship W3197269436A5038860267 @default.
- W3197269436 hasAuthorship W3197269436A5071957113 @default.
- W3197269436 hasAuthorship W3197269436A5080907045 @default.
- W3197269436 hasConcept C100564792 @default.
- W3197269436 hasConcept C113323301 @default.
- W3197269436 hasConcept C126322002 @default.
- W3197269436 hasConcept C134018914 @default.
- W3197269436 hasConcept C142656374 @default.
- W3197269436 hasConcept C151279926 @default.
- W3197269436 hasConcept C155164980 @default.
- W3197269436 hasConcept C160145004 @default.
- W3197269436 hasConcept C163146387 @default.
- W3197269436 hasConcept C170493617 @default.
- W3197269436 hasConcept C171089720 @default.
- W3197269436 hasConcept C185592680 @default.
- W3197269436 hasConcept C2776885963 @default.
- W3197269436 hasConcept C2778938600 @default.
- W3197269436 hasConcept C2780051329 @default.
- W3197269436 hasConcept C2780222073 @default.
- W3197269436 hasConcept C2780642333 @default.
- W3197269436 hasConcept C541997718 @default.
- W3197269436 hasConcept C71924100 @default.
- W3197269436 hasConcept C86803240 @default.
- W3197269436 hasConceptScore W3197269436C100564792 @default.
- W3197269436 hasConceptScore W3197269436C113323301 @default.
- W3197269436 hasConceptScore W3197269436C126322002 @default.
- W3197269436 hasConceptScore W3197269436C134018914 @default.
- W3197269436 hasConceptScore W3197269436C142656374 @default.
- W3197269436 hasConceptScore W3197269436C151279926 @default.
- W3197269436 hasConceptScore W3197269436C155164980 @default.
- W3197269436 hasConceptScore W3197269436C160145004 @default.