FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3197410003> ?p ?o ?g. }

• W3197410003 abstract "Abstract Background Goat, one of the first domesticated livestock, is a worldwide important species both culturally and economically. The current goat reference genome, known as ARS1, is reported as the first nonhuman genome assembly using 69× PacBio sequencing. However, ARS1 suffers from incomplete X chromosome and highly fragmented Y chromosome scaffolds. Results Here, we present a very high-quality de novo genome assembly, Saanen_v1, from a male Saanen dairy goat, with the first goat Y chromosome scaffold based on 117× PacBio long-read sequencing and 118× Hi-C data. Saanen_v1 displays a high level of completeness thanks to the presence of centromeric and telomeric repeats at the proximal and distal ends of two-thirds of the autosomes, and a much reduced number of gaps (169 vs. 773). The completeness and accuracy of the Saanen_v1 genome assembly are also evidenced by more assembled sequences on the chromosomes (2.63 Gb for Saanen_v1 vs. 2.58 Gb for ARS1), a slightly increased mapping ratio for transcriptomic data, and more genes anchored to chromosomes. The eight putative large assembly errors (1 to ~ 7 Mb each) found in ARS1 were amended, and for the first time, the substitution rate of this ruminant Y chromosome was estimated. Furthermore, sequence improvement in Saanen_v1, compared with ARS1, enables us to assign the likely correct positions for 4.4% of the single nucleotide polymorphism (SNP) probes in the widely used GoatSNP50 chip. Conclusions The updated goat genome assembly including both sex chromosomes (X and Y) and the autosomes with high-resolution quality will serve as a valuable resource for goat genetic research and applications." @default.
• W3197410003 created "2021-09-13" @default.
• W3197410003 creator A5000996528 @default.
• W3197410003 creator A5006207753 @default.
• W3197410003 creator A5014282081 @default.
• W3197410003 creator A5015716640 @default.
• W3197410003 creator A5029894657 @default.
• W3197410003 creator A5039921045 @default.
• W3197410003 creator A5040828828 @default.
• W3197410003 creator A5053497577 @default.
• W3197410003 creator A5067521028 @default.
• W3197410003 creator A5068176076 @default.
• W3197410003 date "2021-09-10" @default.
• W3197410003 modified "2023-10-17" @default.
• W3197410003 title "A near complete genome for goat genetic and genomic research" @default.
• W3197410003 cites W1484347389 @default.
• W3197410003 cites W1767772592 @default.
• W3197410003 cites W1969042907 @default.
• W3197410003 cites W1971440252 @default.
• W3197410003 cites W1971545385 @default.
• W3197410003 cites W1973862547 @default.
• W3197410003 cites W1974640383 @default.
• W3197410003 cites W1982855075 @default.
• W3197410003 cites W1984068087 @default.
• W3197410003 cites W1998422171 @default.
• W3197410003 cites W2041389096 @default.
• W3197410003 cites W2063287758 @default.
• W3197410003 cites W2074956582 @default.
• W3197410003 cites W2091851394 @default.
• W3197410003 cites W2095685450 @default.
• W3197410003 cites W2102278945 @default.
• W3197410003 cites W2102619694 @default.
• W3197410003 cites W2104005232 @default.
• W3197410003 cites W2104775949 @default.
• W3197410003 cites W2105191441 @default.
• W3197410003 cites W2106678197 @default.
• W3197410003 cites W2108108770 @default.
• W3197410003 cites W2108234281 @default.
• W3197410003 cites W2112132489 @default.
• W3197410003 cites W2113395514 @default.
• W3197410003 cites W2128505445 @default.
• W3197410003 cites W2130305733 @default.
• W3197410003 cites W2131596369 @default.
• W3197410003 cites W2132011705 @default.
• W3197410003 cites W2132417050 @default.
• W3197410003 cites W2136145671 @default.
• W3197410003 cites W2141274012 @default.
• W3197410003 cites W2141458291 @default.
• W3197410003 cites W2142678478 @default.
• W3197410003 cites W2149066274 @default.
• W3197410003 cites W2149597669 @default.
• W3197410003 cites W2155628349 @default.
• W3197410003 cites W2162758337 @default.
• W3197410003 cites W2169456326 @default.
• W3197410003 cites W2216234219 @default.
• W3197410003 cites W2279222810 @default.
• W3197410003 cites W2326614276 @default.
• W3197410003 cites W2396077153 @default.
• W3197410003 cites W2422772473 @default.
• W3197410003 cites W2481029670 @default.
• W3197410003 cites W2493763501 @default.
• W3197410003 cites W2531587846 @default.
• W3197410003 cites W2575750030 @default.
• W3197410003 cites W2594081754 @default.
• W3197410003 cites W2595696008 @default.
• W3197410003 cites W2600599045 @default.
• W3197410003 cites W2615786037 @default.
• W3197410003 cites W2755804176 @default.
• W3197410003 cites W2788194819 @default.
• W3197410003 cites W2788228074 @default.
• W3197410003 cites W2789843538 @default.
• W3197410003 cites W2795787441 @default.
• W3197410003 cites W2883380562 @default.
• W3197410003 cites W2897774129 @default.
• W3197410003 cites W2898440040 @default.
• W3197410003 cites W2900417598 @default.
• W3197410003 cites W2900702659 @default.
• W3197410003 cites W2901214479 @default.
• W3197410003 cites W2901795552 @default.
• W3197410003 cites W2901944768 @default.
• W3197410003 cites W2910586282 @default.
• W3197410003 cites W2910863997 @default.
• W3197410003 cites W2951470692 @default.
• W3197410003 cites W2951912016 @default.
• W3197410003 cites W2968499116 @default.
• W3197410003 cites W2975391841 @default.
• W3197410003 cites W2989100769 @default.
• W3197410003 cites W2992976869 @default.
• W3197410003 cites W3007172120 @default.
• W3197410003 cites W3030496926 @default.
• W3197410003 cites W3042374389 @default.
• W3197410003 cites W3045473232 @default.
• W3197410003 cites W3048295938 @default.
• W3197410003 cites W3089638647 @default.
• W3197410003 cites W3090950993 @default.
• W3197410003 cites W3113162057 @default.
• W3197410003 cites W3148425969 @default.
• W3197410003 cites W3163990482 @default.
• W3197410003 cites W4247053599 @default.
• W3197410003 doi "https://doi.org/10.1186/s12711-021-00668-5" @default.

• next