Matches in SemOpenAlex for { <https://semopenalex.org/work/W3197432011> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W3197432011 abstract "Abstract Tilapia is one of the most consumed farmed fish, which requires the use of antibiotics in certain phases of its production. This study assessed the safety of 30 days of oral florfenicol (FFC)-dosing at 0-10 times the therapeutic dose (1X: 10 mg/kg biomass/day) in Oreochromis niloticus juveniles. Behavioural changes, feed consumption, mortality and biomass were evaluated. Besides, the levels of serum glucose, calcium, chloride, creatinine, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and blood cell morphology were determined at scheduled intervals. The 30 days of oral FFC-dosing caused 3.33% (1X) to 18.33% (10X) mortalities, reduced feed intake and biomass in a dose-dependent manner. The fish fed the therapeutic dose recorded 1.25 folds increase in biomass; while the control group recorded 1.45 folds increase in 30 days. No significant erythrocyte morphological alterations were observed in the 1X group compared to the control. However, marked morphological alterations like tear-shaped, spindle-shaped and degenerative erythrocytes in higher dosing groups indicated FFC cytotoxicity. All the serum biomarkers of O. niloticus increased significantly on day 10 and day 30 FFC-dosing in a dose-dependent manner, except for calcium and chloride, which reduced significantly during the dosing period. Within 2 weeks of suspension of FFC-dosing, the serum biomarker levels became normal except for alkaline phosphatase and creatinine. The recovery of biomass, feed intake, serum biomarker levels and erythrocyte morphological changes suggested that the FFC induced changes are reversible. This study has, thus, proclaimed the safety of FFC at the therapeutic dose in O. niloticus ." @default.
- W3197432011 created "2021-09-13" @default.
- W3197432011 creator A5000146289 @default.
- W3197432011 creator A5032509373 @default.
- W3197432011 creator A5042870347 @default.
- W3197432011 creator A5079288493 @default.
- W3197432011 creator A5079877588 @default.
- W3197432011 creator A5080106967 @default.
- W3197432011 date "2021-09-03" @default.
- W3197432011 modified "2023-09-25" @default.
- W3197432011 title "Effects of Extended Feeding of Florfenicol Coated Medicated Diets on the Safety, Serum Biomarkers and Blood Cells Morphology of Nile Tilapia Oreochromis Niloticus (L.) Juveniles" @default.
- W3197432011 doi "https://doi.org/10.21203/rs.3.rs-707214/v1" @default.
- W3197432011 hasPublicationYear "2021" @default.
- W3197432011 type Work @default.
- W3197432011 sameAs 3197432011 @default.
- W3197432011 citedByCount "0" @default.
- W3197432011 crossrefType "posted-content" @default.
- W3197432011 hasAuthorship W3197432011A5000146289 @default.
- W3197432011 hasAuthorship W3197432011A5032509373 @default.
- W3197432011 hasAuthorship W3197432011A5042870347 @default.
- W3197432011 hasAuthorship W3197432011A5079288493 @default.
- W3197432011 hasAuthorship W3197432011A5079877588 @default.
- W3197432011 hasAuthorship W3197432011A5080106967 @default.
- W3197432011 hasBestOaLocation W31974320111 @default.
- W3197432011 hasConcept C126322002 @default.
- W3197432011 hasConcept C134018914 @default.
- W3197432011 hasConcept C140793950 @default.
- W3197432011 hasConcept C160160445 @default.
- W3197432011 hasConcept C181199279 @default.
- W3197432011 hasConcept C185592680 @default.
- W3197432011 hasConcept C2777288759 @default.
- W3197432011 hasConcept C2778658382 @default.
- W3197432011 hasConcept C2779286987 @default.
- W3197432011 hasConcept C2780129523 @default.
- W3197432011 hasConcept C2780306776 @default.
- W3197432011 hasConcept C2780663544 @default.
- W3197432011 hasConcept C2909208804 @default.
- W3197432011 hasConcept C501593827 @default.
- W3197432011 hasConcept C505870484 @default.
- W3197432011 hasConcept C55493867 @default.
- W3197432011 hasConcept C71924100 @default.
- W3197432011 hasConcept C86803240 @default.
- W3197432011 hasConcept C98274493 @default.
- W3197432011 hasConceptScore W3197432011C126322002 @default.
- W3197432011 hasConceptScore W3197432011C134018914 @default.
- W3197432011 hasConceptScore W3197432011C140793950 @default.
- W3197432011 hasConceptScore W3197432011C160160445 @default.
- W3197432011 hasConceptScore W3197432011C181199279 @default.
- W3197432011 hasConceptScore W3197432011C185592680 @default.
- W3197432011 hasConceptScore W3197432011C2777288759 @default.
- W3197432011 hasConceptScore W3197432011C2778658382 @default.
- W3197432011 hasConceptScore W3197432011C2779286987 @default.
- W3197432011 hasConceptScore W3197432011C2780129523 @default.
- W3197432011 hasConceptScore W3197432011C2780306776 @default.
- W3197432011 hasConceptScore W3197432011C2780663544 @default.
- W3197432011 hasConceptScore W3197432011C2909208804 @default.
- W3197432011 hasConceptScore W3197432011C501593827 @default.
- W3197432011 hasConceptScore W3197432011C505870484 @default.
- W3197432011 hasConceptScore W3197432011C55493867 @default.
- W3197432011 hasConceptScore W3197432011C71924100 @default.
- W3197432011 hasConceptScore W3197432011C86803240 @default.
- W3197432011 hasConceptScore W3197432011C98274493 @default.
- W3197432011 hasLocation W31974320111 @default.
- W3197432011 hasOpenAccess W3197432011 @default.
- W3197432011 hasPrimaryLocation W31974320111 @default.
- W3197432011 hasRelatedWork W129995498 @default.
- W3197432011 hasRelatedWork W1972573590 @default.
- W3197432011 hasRelatedWork W2045983418 @default.
- W3197432011 hasRelatedWork W2065402343 @default.
- W3197432011 hasRelatedWork W2105611246 @default.
- W3197432011 hasRelatedWork W2127403563 @default.
- W3197432011 hasRelatedWork W2130083249 @default.
- W3197432011 hasRelatedWork W2207044775 @default.
- W3197432011 hasRelatedWork W3020740466 @default.
- W3197432011 hasRelatedWork W4382195811 @default.
- W3197432011 isParatext "false" @default.
- W3197432011 isRetracted "false" @default.
- W3197432011 magId "3197432011" @default.
- W3197432011 workType "article" @default.