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- W3197479968 abstract "In biology, H2O2 plays an important role as a component of oxidative stress and as a signaling molecule. This chapter describes the discovery and properties of H2O2, arguing that this molecule is not as reactive as often thought, and focusing on the Fenton reaction, as for decades this reaction illustrated the bad side of H2O2. The more recently discovered role of H2O2 as a redox mediator and messenger represents its good side. These two aspects define H2O2, a molecule with a Janus face. During the 1970s, the Fenton reaction was proposed as the causative agent of oxidative damage because it produced the reactive hydroxyl radical. The origin of the Fenton reaction was a case of serendipity. Thenard tested whether H2O2 reacted with many compounds—inorganic and organic. Scavenging of H2O2 by catalase and glutathione peroxidase is fast. Nature uses a trick to accelerate the reaction with the peroxidative cysteine in peroxiredoxin." @default.
- W3197479968 created "2021-09-13" @default.
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- W3197479968 date "2017-10-19" @default.
- W3197479968 modified "2023-09-26" @default.
- W3197479968 title "Hydrogen Peroxide, a Molecule with a Janus Face" @default.
- W3197479968 doi "https://doi.org/10.1201/9781315154831-1" @default.
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