Matches in SemOpenAlex for { <https://semopenalex.org/work/W3197482320> ?p ?o ?g. }
- W3197482320 endingPage "9281" @default.
- W3197482320 startingPage "9281" @default.
- W3197482320 abstract "Neonatal lupus erythematosus (NLE) is a syndrome of clinical symptoms observed in neonates born to mothers with antibodies to soluble antigens of the cell nucleus. The main factors contributing to the pathogenesis of this disease are anti-Sjögren Syndrome A (anti-SS-A) antibodies, known as anti-Ro, and anti-Sjögren Syndrome B (anti-SS-B) antibodies, known as anti-La. Recent publications have also shown the significant role of anti-ribonucleoprotein antibodies (anti-RNP). Seropositive mothers may have a diagnosed rheumatic disease or they can be asymptomatic without diagnosis at the time of childbirth. These antibodies, after crossing the placenta, may trigger a cascade of inflammatory reactions. The symptoms of NLE can be divided into reversible symptoms, which concern skin, hematological, and hepatological changes, but 2% of children develop irreversible symptoms, which include disturbances of the cardiac stimulatory and conduction system. Preconceptive care and pharmacological prophylaxis of NLE in the case of mothers from the risk group are important, as well as the monitoring of the clinical condition of the mother and fetus throughout pregnancy and the neonatal period. The aim of this manuscript is to summarize the previous literature and current state of knowledge about neonatal lupus and to discuss the role of anti-Ro in the inflammatory process." @default.
- W3197482320 created "2021-09-13" @default.
- W3197482320 creator A5003538370 @default.
- W3197482320 creator A5047033173 @default.
- W3197482320 creator A5048152362 @default.
- W3197482320 creator A5070761667 @default.
- W3197482320 date "2021-08-27" @default.
- W3197482320 modified "2023-10-18" @default.
- W3197482320 title "An Overview of Neonatal Lupus with Anti-Ro Characteristics" @default.
- W3197482320 cites W1146019334 @default.
- W3197482320 cites W126384489 @default.
- W3197482320 cites W1505676752 @default.
- W3197482320 cites W1580582366 @default.
- W3197482320 cites W1613576600 @default.
- W3197482320 cites W187712674 @default.
- W3197482320 cites W1896518728 @default.
- W3197482320 cites W1964495124 @default.
- W3197482320 cites W1966898148 @default.
- W3197482320 cites W1969108300 @default.
- W3197482320 cites W1970594753 @default.
- W3197482320 cites W1970726851 @default.
- W3197482320 cites W1978023215 @default.
- W3197482320 cites W1979198249 @default.
- W3197482320 cites W1982583911 @default.
- W3197482320 cites W1982764945 @default.
- W3197482320 cites W1984381472 @default.
- W3197482320 cites W1985637111 @default.
- W3197482320 cites W1985650205 @default.
- W3197482320 cites W1986167000 @default.
- W3197482320 cites W1992346462 @default.
- W3197482320 cites W2002256390 @default.
- W3197482320 cites W2004064425 @default.
- W3197482320 cites W2005468802 @default.
- W3197482320 cites W2005700136 @default.
- W3197482320 cites W2014425110 @default.
- W3197482320 cites W2017688622 @default.
- W3197482320 cites W2020191588 @default.
- W3197482320 cites W2021608402 @default.
- W3197482320 cites W2024562564 @default.
- W3197482320 cites W2027483655 @default.
- W3197482320 cites W2034508361 @default.
- W3197482320 cites W2040657208 @default.
- W3197482320 cites W2042848281 @default.
- W3197482320 cites W2043318620 @default.
- W3197482320 cites W2044438526 @default.
- W3197482320 cites W2046088649 @default.
- W3197482320 cites W2050307682 @default.
- W3197482320 cites W2052839110 @default.
- W3197482320 cites W2054992677 @default.
- W3197482320 cites W2062531865 @default.
- W3197482320 cites W2062920936 @default.
- W3197482320 cites W2062944200 @default.
- W3197482320 cites W2065382314 @default.
- W3197482320 cites W2066611631 @default.
- W3197482320 cites W2067319956 @default.
- W3197482320 cites W2067401055 @default.
- W3197482320 cites W2070527591 @default.
- W3197482320 cites W2071510385 @default.
- W3197482320 cites W2072019856 @default.
- W3197482320 cites W2077442450 @default.
- W3197482320 cites W2080285185 @default.
- W3197482320 cites W2089169921 @default.
- W3197482320 cites W2090022336 @default.
- W3197482320 cites W2096303318 @default.
- W3197482320 cites W2097558397 @default.
- W3197482320 cites W2105012582 @default.
- W3197482320 cites W2105050154 @default.
- W3197482320 cites W2111349115 @default.
- W3197482320 cites W2112321962 @default.
- W3197482320 cites W2112559914 @default.
- W3197482320 cites W2112762103 @default.
- W3197482320 cites W2113337391 @default.
- W3197482320 cites W2122237506 @default.
- W3197482320 cites W2122543047 @default.
- W3197482320 cites W2125111321 @default.
- W3197482320 cites W2131946904 @default.
- W3197482320 cites W2135467756 @default.
- W3197482320 cites W2135804917 @default.
- W3197482320 cites W2143834163 @default.
- W3197482320 cites W2144759405 @default.
- W3197482320 cites W2145904199 @default.
- W3197482320 cites W2146203649 @default.
- W3197482320 cites W2148352424 @default.
- W3197482320 cites W2152232379 @default.
- W3197482320 cites W2159594593 @default.
- W3197482320 cites W2164993846 @default.
- W3197482320 cites W2165748310 @default.
- W3197482320 cites W2170200935 @default.
- W3197482320 cites W2170700381 @default.
- W3197482320 cites W2313782591 @default.
- W3197482320 cites W2563957495 @default.
- W3197482320 cites W2566914768 @default.
- W3197482320 cites W2568588168 @default.
- W3197482320 cites W2582392664 @default.
- W3197482320 cites W2589015752 @default.
- W3197482320 cites W2613460218 @default.
- W3197482320 cites W2619329188 @default.
- W3197482320 cites W2729029988 @default.