FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3197560997> ?p ?o ?g. }

• W3197560997 endingPage "e93" @default.
• W3197560997 startingPage "e91" @default.
• W3197560997 abstract "Excitation-contraction coupling (ECC) converts electrical stimuli to mechanical responses. Herein we provide a concise summary of the most updated insights on, and nomenclature of, the main actors involved in cardiac ECC, posing the basis for pharmacologic interventions in heart failure (HF) and arrhythmias. Recently introduced therapeutic strategies targeting myocardial ECC are appraised as well, specifying their molecular mechanism of action. Excitation-contraction coupling starts with the entry of Ca2+ into the cardiomyocyte through the L-type Ca2+ channels (LTCC, also known as dihydropyridine channel); this step triggers Ca2+-induced Ca2+-release from the sarcoplasmic reticulum (SR) by activating type 2 ryanodine receptor Ca2+ release channel (RyR2).1 Ca2+-releasing units consisting of closely (∼15 nm) approximated LTCCs (on T-tubules, which are invaginations of the sarcolemma with a diameter of ∼200 nm that form a highly branched network) and RyRs (on the SR) are known as dyadic..." @default.
• W3197560997 created "2021-09-13" @default.
• W3197560997 creator A5015296039 @default.
• W3197560997 creator A5019034390 @default.
• W3197560997 creator A5039574996 @default.
• W3197560997 creator A5046754209 @default.
• W3197560997 creator A5063609039 @default.
• W3197560997 creator A5074415719 @default.
• W3197560997 date "2021-09-09" @default.
• W3197560997 modified "2023-09-29" @default.
• W3197560997 title "Advances in the understanding of excitation-contraction coupling: the pulsing quest for drugs against heart failure and arrhythmias" @default.
• W3197560997 cites W2757102228 @default.
• W3197560997 cites W2950048818 @default.
• W3197560997 cites W2995407169 @default.
• W3197560997 cites W3013207865 @default.
• W3197560997 cites W3094301295 @default.
• W3197560997 cites W3098430919 @default.
• W3197560997 cites W3146007573 @default.
• W3197560997 cites W3147808645 @default.
• W3197560997 cites W3155104039 @default.
• W3197560997 cites W3193922103 @default.
• W3197560997 doi "https://doi.org/10.1093/ehjcvp/pvab069" @default.
• W3197560997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34498676" @default.
• W3197560997 hasPublicationYear "2021" @default.
• W3197560997 type Work @default.
• W3197560997 sameAs 3197560997 @default.
• W3197560997 citedByCount "14" @default.
• W3197560997 countsByYear W31975609972021 @default.
• W3197560997 countsByYear W31975609972022 @default.
• W3197560997 countsByYear W31975609972023 @default.
• W3197560997 crossrefType "journal-article" @default.
• W3197560997 hasAuthorship W3197560997A5015296039 @default.
• W3197560997 hasAuthorship W3197560997A5019034390 @default.
• W3197560997 hasAuthorship W3197560997A5039574996 @default.
• W3197560997 hasAuthorship W3197560997A5046754209 @default.
• W3197560997 hasAuthorship W3197560997A5063609039 @default.
• W3197560997 hasAuthorship W3197560997A5074415719 @default.
• W3197560997 hasBestOaLocation W31975609972 @default.
• W3197560997 hasConcept C113217602 @default.
• W3197560997 hasConcept C114908165 @default.
• W3197560997 hasConcept C12554922 @default.
• W3197560997 hasConcept C126322002 @default.
• W3197560997 hasConcept C131584629 @default.
• W3197560997 hasConcept C158617107 @default.
• W3197560997 hasConcept C163415756 @default.
• W3197560997 hasConcept C164705383 @default.
• W3197560997 hasConcept C185592680 @default.
• W3197560997 hasConcept C190712762 @default.
• W3197560997 hasConcept C191897082 @default.
• W3197560997 hasConcept C192562407 @default.
• W3197560997 hasConcept C199096232 @default.
• W3197560997 hasConcept C207200792 @default.
• W3197560997 hasConcept C2778198053 @default.
• W3197560997 hasConcept C2781212610 @default.
• W3197560997 hasConcept C519063684 @default.
• W3197560997 hasConcept C55493867 @default.
• W3197560997 hasConcept C71924100 @default.
• W3197560997 hasConcept C86803240 @default.
• W3197560997 hasConceptScore W3197560997C113217602 @default.
• W3197560997 hasConceptScore W3197560997C114908165 @default.
• W3197560997 hasConceptScore W3197560997C12554922 @default.
• W3197560997 hasConceptScore W3197560997C126322002 @default.
• W3197560997 hasConceptScore W3197560997C131584629 @default.
• W3197560997 hasConceptScore W3197560997C158617107 @default.
• W3197560997 hasConceptScore W3197560997C163415756 @default.
• W3197560997 hasConceptScore W3197560997C164705383 @default.
• W3197560997 hasConceptScore W3197560997C185592680 @default.
• W3197560997 hasConceptScore W3197560997C190712762 @default.
• W3197560997 hasConceptScore W3197560997C191897082 @default.
• W3197560997 hasConceptScore W3197560997C192562407 @default.
• W3197560997 hasConceptScore W3197560997C199096232 @default.
• W3197560997 hasConceptScore W3197560997C207200792 @default.
• W3197560997 hasConceptScore W3197560997C2778198053 @default.
• W3197560997 hasConceptScore W3197560997C2781212610 @default.
• W3197560997 hasConceptScore W3197560997C519063684 @default.
• W3197560997 hasConceptScore W3197560997C55493867 @default.
• W3197560997 hasConceptScore W3197560997C71924100 @default.
• W3197560997 hasConceptScore W3197560997C86803240 @default.
• W3197560997 hasFunder F4320332161 @default.
• W3197560997 hasIssue "6" @default.
• W3197560997 hasLocation W31975609971 @default.
• W3197560997 hasLocation W31975609972 @default.
• W3197560997 hasLocation W31975609973 @default.
• W3197560997 hasOpenAccess W3197560997 @default.
• W3197560997 hasPrimaryLocation W31975609971 @default.
• W3197560997 hasRelatedWork W1964461691 @default.
• W3197560997 hasRelatedWork W1977626206 @default.
• W3197560997 hasRelatedWork W2025425117 @default.
• W3197560997 hasRelatedWork W2026556538 @default.
• W3197560997 hasRelatedWork W2060592179 @default.
• W3197560997 hasRelatedWork W2062131013 @default.
• W3197560997 hasRelatedWork W2094910653 @default.
• W3197560997 hasRelatedWork W2149117830 @default.
• W3197560997 hasRelatedWork W2393834569 @default.
• W3197560997 hasRelatedWork W4242327605 @default.
• W3197560997 hasVolume "7" @default.
• W3197560997 isParatext "false" @default.
• W3197560997 isRetracted "false" @default.

• next