Matches in SemOpenAlex for { <https://semopenalex.org/work/W3197627867> ?p ?o ?g. }
- W3197627867 endingPage "928" @default.
- W3197627867 startingPage "916" @default.
- W3197627867 abstract "Nutrient transition metals are required cofactors for many proteins to perform functions necessary for life. As such, the concentration of nutrient metals is carefully maintained to retain critical biological processes while limiting toxicity. During infection, invading bacterial pathogens must acquire essential metals, such as zinc, manganese, iron, and copper, from the host to colonize and cause disease. To combat this, the host exploits the essentiality and toxicity of nutrient metals by producing factors that limit metal availability, thereby starving pathogens or accumulating metals in excess to intoxicate the pathogen in a process termed 'nutritional immunity'. As a result of inflammation, a heterogeneous environment containing both metal-replete and -deplete niches is created, in which nutrient metal availability may have an underappreciated role in regulating immune cell function during infection. How the host manipulates nutrient metal availability during infection, and the downstream effects that nutrient metals and metal-sequestering proteins have on immune cell function, are discussed in this review." @default.
- W3197627867 created "2021-09-13" @default.
- W3197627867 creator A5008243647 @default.
- W3197627867 creator A5082616273 @default.
- W3197627867 date "2021-11-01" @default.
- W3197627867 modified "2023-10-05" @default.
- W3197627867 title "The impact of metal availability on immune function during infection" @default.
- W3197627867 cites W112184077 @default.
- W3197627867 cites W1143127356 @default.
- W3197627867 cites W1494810979 @default.
- W3197627867 cites W150428852 @default.
- W3197627867 cites W1531010890 @default.
- W3197627867 cites W1534995493 @default.
- W3197627867 cites W1540343372 @default.
- W3197627867 cites W1589237240 @default.
- W3197627867 cites W1591767079 @default.
- W3197627867 cites W1600690434 @default.
- W3197627867 cites W170557967 @default.
- W3197627867 cites W1758183764 @default.
- W3197627867 cites W1831821781 @default.
- W3197627867 cites W1886262751 @default.
- W3197627867 cites W1898868640 @default.
- W3197627867 cites W1930054223 @default.
- W3197627867 cites W1930655854 @default.
- W3197627867 cites W1939739894 @default.
- W3197627867 cites W1954443227 @default.
- W3197627867 cites W1964339096 @default.
- W3197627867 cites W1964818207 @default.
- W3197627867 cites W1965919540 @default.
- W3197627867 cites W1966289113 @default.
- W3197627867 cites W1970399857 @default.
- W3197627867 cites W1974103263 @default.
- W3197627867 cites W1975662724 @default.
- W3197627867 cites W1976665224 @default.
- W3197627867 cites W1976906238 @default.
- W3197627867 cites W1977581754 @default.
- W3197627867 cites W1979135961 @default.
- W3197627867 cites W1979194107 @default.
- W3197627867 cites W1980042430 @default.
- W3197627867 cites W1983435829 @default.
- W3197627867 cites W1983463779 @default.
- W3197627867 cites W1984007101 @default.
- W3197627867 cites W1987287925 @default.
- W3197627867 cites W1987816685 @default.
- W3197627867 cites W1988495042 @default.
- W3197627867 cites W1989502748 @default.
- W3197627867 cites W1992196644 @default.
- W3197627867 cites W1993284336 @default.
- W3197627867 cites W199400172 @default.
- W3197627867 cites W1996641418 @default.
- W3197627867 cites W1998414732 @default.
- W3197627867 cites W1999602990 @default.
- W3197627867 cites W2000707384 @default.
- W3197627867 cites W2002169560 @default.
- W3197627867 cites W2003345560 @default.
- W3197627867 cites W2006700192 @default.
- W3197627867 cites W2007440356 @default.
- W3197627867 cites W2007753170 @default.
- W3197627867 cites W2009145423 @default.
- W3197627867 cites W2011005794 @default.
- W3197627867 cites W2011515525 @default.
- W3197627867 cites W2011537701 @default.
- W3197627867 cites W2012843090 @default.
- W3197627867 cites W2016802844 @default.
- W3197627867 cites W2017730533 @default.
- W3197627867 cites W2017764078 @default.
- W3197627867 cites W2018045909 @default.
- W3197627867 cites W2020941408 @default.
- W3197627867 cites W2021127061 @default.
- W3197627867 cites W2021581026 @default.
- W3197627867 cites W2022017052 @default.
- W3197627867 cites W2022047884 @default.
- W3197627867 cites W2022200394 @default.
- W3197627867 cites W2025059479 @default.
- W3197627867 cites W2026669552 @default.
- W3197627867 cites W2028552033 @default.
- W3197627867 cites W2029728009 @default.
- W3197627867 cites W2031283301 @default.
- W3197627867 cites W2034156020 @default.
- W3197627867 cites W2034252508 @default.
- W3197627867 cites W2035152237 @default.
- W3197627867 cites W2040988988 @default.
- W3197627867 cites W2042811693 @default.
- W3197627867 cites W2042934444 @default.
- W3197627867 cites W2045230147 @default.
- W3197627867 cites W2045970401 @default.
- W3197627867 cites W2048131709 @default.
- W3197627867 cites W2054203906 @default.
- W3197627867 cites W2055357260 @default.
- W3197627867 cites W2056915088 @default.
- W3197627867 cites W2059080581 @default.
- W3197627867 cites W2060342018 @default.
- W3197627867 cites W2062382507 @default.
- W3197627867 cites W2063263528 @default.
- W3197627867 cites W2063635739 @default.
- W3197627867 cites W2065326187 @default.
- W3197627867 cites W2065338876 @default.
- W3197627867 cites W2067676497 @default.