FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3197648370> ?p ?o ?g. }

• W3197648370 endingPage "62" @default.
• W3197648370 startingPage "55" @default.
• W3197648370 abstract "There is some evidence of cortical hyper-excitability in Alzheimer's Dementia (AD) but its relationship with cognition is not clear. In this study, we assessed dorsolateral prefrontal cortex (DLPFC) excitability and its relationship with cognition in AD. Twenty-four participants with AD (mean [SD] age = 74.1 [7.2] years) and eleven elderly healthy controls (HC) (mean [SD] age = 68.8 [7.3] years) were recruited. Transcranial magnetic stimulation (TMS) combined with electroencephalography (EEG) was used to assess cortical excitability. Cortical evoked activity (CEA) between 25 and 80 ms post-TMS stimulus was calculated as the primary measure of cortical excitability. TMS-evoked potential peak (TEP) amplitudes (P30, N45 and P60) were also calculated. Cognition was assessed using Montreal Cognitive Assessment (MoCA), Executive Interview (EXIT) and Cambridge Neuropsychological Test Automated Battery Stockings of Cambridge (SOC). There was no difference in TMS stimulus intensity between the groups. DLPFC-CEA was higher in the AD (mean [SD] = 134.64 [90.22] μV) than the HC group (mean [SD] = 82.65 [40.28] μV; t33 = 2.357, p = 0.025). There were no differences in TEP peak amplitudes between the groups. Further, DLPFC-CEA was inversely associated with MoCA and SOC, and positively associated with EXIT scores in AD. These results suggest increased DLPFC excitability in AD, and its inverse associations with global cognition and executive function. Future studies should examine these findings in larger samples and longitudinally, and could also assess these markers of cortical excitability in relation to other established markers of AD and in response to interventions." @default.
• W3197648370 created "2021-09-13" @default.
• W3197648370 creator A5000921316 @default.
• W3197648370 creator A5003880874 @default.
• W3197648370 creator A5004751576 @default.
• W3197648370 creator A5019562259 @default.
• W3197648370 creator A5024729479 @default.
• W3197648370 creator A5046597133 @default.
• W3197648370 creator A5052979912 @default.
• W3197648370 creator A5058738658 @default.
• W3197648370 creator A5064979886 @default.
• W3197648370 creator A5070114450 @default.
• W3197648370 creator A5082357914 @default.
• W3197648370 date "2021-11-01" @default.
• W3197648370 modified "2023-10-13" @default.
• W3197648370 title "Dorsolateral prefrontal cortex excitability abnormalities in Alzheimer's Dementia: Findings from transcranial magnetic stimulation and electroencephalography study" @default.
• W3197648370 cites W1496689787 @default.
• W3197648370 cites W1514687927 @default.
• W3197648370 cites W1793154169 @default.
• W3197648370 cites W1831658031 @default.
• W3197648370 cites W1855610705 @default.
• W3197648370 cites W1859821439 @default.
• W3197648370 cites W1894814115 @default.
• W3197648370 cites W1967100290 @default.
• W3197648370 cites W1970910654 @default.
• W3197648370 cites W1973530337 @default.
• W3197648370 cites W1979152340 @default.
• W3197648370 cites W1983288195 @default.
• W3197648370 cites W1984828228 @default.
• W3197648370 cites W1985060509 @default.
• W3197648370 cites W1986251019 @default.
• W3197648370 cites W1988928342 @default.
• W3197648370 cites W1990207779 @default.
• W3197648370 cites W1992885267 @default.
• W3197648370 cites W1996446023 @default.
• W3197648370 cites W1997417397 @default.
• W3197648370 cites W2004852048 @default.
• W3197648370 cites W2008632993 @default.
• W3197648370 cites W2008943882 @default.
• W3197648370 cites W2014344734 @default.
• W3197648370 cites W2019148392 @default.
• W3197648370 cites W2020460747 @default.
• W3197648370 cites W2023200476 @default.
• W3197648370 cites W2029854254 @default.
• W3197648370 cites W2035466313 @default.
• W3197648370 cites W2042852371 @default.
• W3197648370 cites W2047846607 @default.
• W3197648370 cites W2048685634 @default.
• W3197648370 cites W2048895129 @default.
• W3197648370 cites W2053836765 @default.
• W3197648370 cites W2069421385 @default.
• W3197648370 cites W2074522737 @default.
• W3197648370 cites W2079819502 @default.
• W3197648370 cites W2081355779 @default.
• W3197648370 cites W2082151254 @default.
• W3197648370 cites W2094815752 @default.
• W3197648370 cites W2098676436 @default.
• W3197648370 cites W2101596363 @default.
• W3197648370 cites W2102997059 @default.
• W3197648370 cites W2103064125 @default.
• W3197648370 cites W2108151962 @default.
• W3197648370 cites W2109221379 @default.
• W3197648370 cites W2109807300 @default.
• W3197648370 cites W2115017507 @default.
• W3197648370 cites W2119583212 @default.
• W3197648370 cites W2127724900 @default.
• W3197648370 cites W2138878035 @default.
• W3197648370 cites W2140358254 @default.
• W3197648370 cites W2142367912 @default.
• W3197648370 cites W2147040438 @default.
• W3197648370 cites W2150319801 @default.
• W3197648370 cites W2151393950 @default.
• W3197648370 cites W2158869838 @default.
• W3197648370 cites W2163301650 @default.
• W3197648370 cites W2165758561 @default.
• W3197648370 cites W2235618559 @default.
• W3197648370 cites W2292081673 @default.
• W3197648370 cites W2292821836 @default.
• W3197648370 cites W2344080161 @default.
• W3197648370 cites W2473313434 @default.
• W3197648370 cites W2505044368 @default.
• W3197648370 cites W2508153574 @default.
• W3197648370 cites W2527558243 @default.
• W3197648370 cites W2552919132 @default.
• W3197648370 cites W2766167500 @default.
• W3197648370 cites W2805618005 @default.
• W3197648370 cites W2884558575 @default.
• W3197648370 cites W2939270612 @default.
• W3197648370 cites W2952572679 @default.
• W3197648370 cites W2996150132 @default.
• W3197648370 cites W3008169983 @default.
• W3197648370 cites W3014879687 @default.
• W3197648370 cites W3037784136 @default.
• W3197648370 cites W3046988908 @default.
• W3197648370 doi "https://doi.org/10.1016/j.ijpsycho.2021.08.008" @default.
• W3197648370 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34499960" @default.
• W3197648370 hasPublicationYear "2021" @default.
• W3197648370 type Work @default.

• next