FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3197653125> ?p ?o ?g. }

• W3197653125 endingPage "H806" @default.
• W3197653125 startingPage "H798" @default.
• W3197653125 abstract "Signal-averaged sympathetic transduction of blood pressure (BP) is inversely related to resting muscle sympathetic nerve activity (MSNA) burst frequency in healthy cohorts. Whether this represents a physiological compensatory adaptation or a methodological limitation, remains unclear. The current analysis aimed to determine the contribution of methodological limitations by evaluating the dependency of MSNA transduction at different levels of absolute BP. Thirty-six healthy participants (27 ± 7 yr, 9 females) underwent resting measures of beat-to-beat heart rate, BP, and muscle sympathetic nerve activity (MSNA). Tertiles of mean arterial pressure (MAP) were computed for each participant to identify cardiac cycles occurring below, around, and above the MAP operating pressure (OP). Changes in hemodynamic variables were computed across 15 cardiac cycles within each MAP tertile to quantify sympathetic transduction. MAP increased irrespective of sympathetic activity when initiated below the OP, but with MSNA bursts provoking larger rises (3.0 ± 0.9 vs. 2.1 ± 0.7 mmHg; P < 0.01). MAP decreased irrespective of sympathetic activity when initiated above the OP, but with MSNA bursts attenuating the drop (-1.3 ± 1.1 vs. -3.1 ± 1.2 mmHg; P < 0.01). In participants with low versus high resting MSNA (12 ± 4 vs. 32 ± 10 bursts/min), sympathetic transduction of MAP was not different when initiated by bursts below (3.2 ± 1.0 vs. 2.8 ± 0.9 mmHg; P = 0.26) and above the OP (-1.0 ± 1.3 vs. -1.6 ± 0.8 mmHg; P = 0.08); however, low resting MSNA was associated with a smaller proportion of MSNA bursts firing above the OP (15 ± 5 vs. 22 ± 5%; P < 0.01). The present analyses demonstrate that the signal-averaging technique for calculating sympathetic transduction of BP is influenced by the timing of an MSNA burst relative to cyclic oscillations in BP.NEW & NOTEWORTHY The current signal-averaging technique for calculating sympathetic transduction of blood pressure does not consider the arterial pressure at which each muscle sympathetic burst occurs. A burst firing when mean arterial pressure is above the operating pressure was associated with a decrease in blood pressure. Thus, individuals with higher muscle sympathetic nerve activity demonstrate a reduced sympathetic transduction owing to the weighted contribution of more sympathetic bursts at higher levels of arterial pressure." @default.
• W3197653125 created "2021-09-13" @default.
• W3197653125 creator A5000907035 @default.
• W3197653125 creator A5016191191 @default.
• W3197653125 creator A5017228450 @default.
• W3197653125 creator A5019417735 @default.
• W3197653125 creator A5021690746 @default.
• W3197653125 creator A5058307719 @default.
• W3197653125 date "2021-10-01" @default.
• W3197653125 modified "2023-10-13" @default.
• W3197653125 title "Blood pressure oscillations impact signal-averaged sympathetic transduction of blood pressure: implications for the association with resting sympathetic outflow" @default.
• W3197653125 cites W1545494857 @default.
• W3197653125 cites W1575064221 @default.
• W3197653125 cites W1580330525 @default.
• W3197653125 cites W1589077211 @default.
• W3197653125 cites W1990765728 @default.
• W3197653125 cites W2004652977 @default.
• W3197653125 cites W2042730494 @default.
• W3197653125 cites W2045092195 @default.
• W3197653125 cites W2118048424 @default.
• W3197653125 cites W2129125192 @default.
• W3197653125 cites W2131029260 @default.
• W3197653125 cites W2139729561 @default.
• W3197653125 cites W2336020467 @default.
• W3197653125 cites W2527483122 @default.
• W3197653125 cites W2600900489 @default.
• W3197653125 cites W2911592862 @default.
• W3197653125 cites W2915634013 @default.
• W3197653125 cites W2951553920 @default.
• W3197653125 cites W2982950049 @default.
• W3197653125 cites W3034035735 @default.
• W3197653125 cites W3048921858 @default.
• W3197653125 cites W3118648896 @default.
• W3197653125 cites W3119920640 @default.
• W3197653125 cites W3151445067 @default.
• W3197653125 cites W3185467839 @default.
• W3197653125 doi "https://doi.org/10.1152/ajpheart.00422.2021" @default.
• W3197653125 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34506224" @default.
• W3197653125 hasPublicationYear "2021" @default.
• W3197653125 type Work @default.
• W3197653125 sameAs 3197653125 @default.
• W3197653125 citedByCount "7" @default.
• W3197653125 countsByYear W31976531252021 @default.
• W3197653125 countsByYear W31976531252022 @default.
• W3197653125 countsByYear W31976531252023 @default.
• W3197653125 crossrefType "journal-article" @default.
• W3197653125 hasAuthorship W3197653125A5000907035 @default.
• W3197653125 hasAuthorship W3197653125A5016191191 @default.
• W3197653125 hasAuthorship W3197653125A5017228450 @default.
• W3197653125 hasAuthorship W3197653125A5019417735 @default.
• W3197653125 hasAuthorship W3197653125A5021690746 @default.
• W3197653125 hasAuthorship W3197653125A5058307719 @default.
• W3197653125 hasConcept C126322002 @default.
• W3197653125 hasConcept C134018914 @default.
• W3197653125 hasConcept C164705383 @default.
• W3197653125 hasConcept C178853913 @default.
• W3197653125 hasConcept C191237925 @default.
• W3197653125 hasConcept C2775898464 @default.
• W3197653125 hasConcept C2776533406 @default.
• W3197653125 hasConcept C2777953023 @default.
• W3197653125 hasConcept C3020789104 @default.
• W3197653125 hasConcept C71924100 @default.
• W3197653125 hasConcept C84393581 @default.
• W3197653125 hasConceptScore W3197653125C126322002 @default.
• W3197653125 hasConceptScore W3197653125C134018914 @default.
• W3197653125 hasConceptScore W3197653125C164705383 @default.
• W3197653125 hasConceptScore W3197653125C178853913 @default.
• W3197653125 hasConceptScore W3197653125C191237925 @default.
• W3197653125 hasConceptScore W3197653125C2775898464 @default.
• W3197653125 hasConceptScore W3197653125C2776533406 @default.
• W3197653125 hasConceptScore W3197653125C2777953023 @default.
• W3197653125 hasConceptScore W3197653125C3020789104 @default.
• W3197653125 hasConceptScore W3197653125C71924100 @default.
• W3197653125 hasConceptScore W3197653125C84393581 @default.
• W3197653125 hasFunder F4320308436 @default.
• W3197653125 hasFunder F4320314607 @default.
• W3197653125 hasFunder F4320319952 @default.
• W3197653125 hasFunder F4320322025 @default.
• W3197653125 hasFunder F4320328039 @default.
• W3197653125 hasFunder F4320334593 @default.
• W3197653125 hasIssue "4" @default.
• W3197653125 hasLocation W31976531251 @default.
• W3197653125 hasLocation W31976531252 @default.
• W3197653125 hasOpenAccess W3197653125 @default.
• W3197653125 hasPrimaryLocation W31976531251 @default.
• W3197653125 hasRelatedWork W1496585796 @default.
• W3197653125 hasRelatedWork W1548914024 @default.
• W3197653125 hasRelatedWork W1988487972 @default.
• W3197653125 hasRelatedWork W1989672093 @default.
• W3197653125 hasRelatedWork W2034533245 @default.
• W3197653125 hasRelatedWork W2093524238 @default.
• W3197653125 hasRelatedWork W2149895566 @default.
• W3197653125 hasRelatedWork W2417877194 @default.
• W3197653125 hasRelatedWork W4299612303 @default.
• W3197653125 hasRelatedWork W4386660092 @default.
• W3197653125 hasVolume "321" @default.
• W3197653125 isParatext "false" @default.
• W3197653125 isRetracted "false" @default.

• next