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- W3197667566 abstract "Silica-based nanoframeworks have been extensively studied for diagnosing and treating hepatocellular carcinoma (HCC). Several reviews have summarized the advantages and disadvantages of these nanoframeworks and their use as drug-delivery carriers. Encouragingly, these nanoframeworks, especially those with metal elements or small molecular drugs doping into the skeleton structure or modifying onto the surface of nanoparticles, could be multifunctional components participating in HCC diagnosis and treatment rather than functioning only as drug-delivery carriers. Therefore, in this work, we described the research progress of silica-based nanoframeworks involved in HCC diagnosis (plasma biomarker detection, magnetic resonance imaging, positron emission tomography, photoacoustic imaging, fluorescent imaging, ultrasonography, etc.) and treatment (chemotherapy, ferroptotic therapy, radiotherapy, phototherapy, sonodynamic therapy, immunotherapy, etc.) to clarify their roles in HCC theranostics. Further, the future expectations and challenges associated with silica-based nanoframeworks were highlighted. We believe that this review will provide a comprehensive understanding for researchers to design novel, functional silica-based nanoframeworks that can effectively overcome HCC." @default.
- W3197667566 created "2021-09-13" @default.
- W3197667566 creator A5002318539 @default.
- W3197667566 creator A5014921394 @default.
- W3197667566 creator A5016250292 @default.
- W3197667566 creator A5023333681 @default.
- W3197667566 creator A5027624215 @default.
- W3197667566 creator A5035659468 @default.
- W3197667566 creator A5056949279 @default.
- W3197667566 creator A5061271427 @default.
- W3197667566 creator A5062632432 @default.
- W3197667566 creator A5070506366 @default.
- W3197667566 creator A5074140059 @default.
- W3197667566 date "2021-09-07" @default.
- W3197667566 modified "2023-09-23" @default.
- W3197667566 title "Silica-Based Nanoframeworks Involved Hepatocellular Carcinoma Theranostic" @default.
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