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- W3197692076 abstract "Carbon tetrachloride injected into young rats on a 10 per cent casein diet deficient in vitamin E resulted in a decrease, to less than one-third of the control value, in the ability of liver slice to synthesize creatine from guanidoacetic acid and methionine. Muscle creatine diminished significantly, urine creatine increased three-fold, and liver creatine increased slightly. The same changes to a lesser degree were noted in vitamin E deficient rats. Dietary vitamin E prevented, or markedly lessened the changes in creatine metabolism due to carbon tetrachloride. These results were interpreted as showing that under the conditions employed, the toxicity of carbon tetrachloride was due to precipitation of an acute vitamin E deficiency. The level of carbon tetrachloride injected (0.05 ml./wk.) was sufficiently low so that no extensive damage to cellular composition or architecture of the liver occurred." @default.
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- W3197692076 date "2021-09-06" @default.
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- W3197692076 title "Intestinal ultrasonography: a useful skill for efficient, non-invasive monitoring of patients with IBD using a clinic-based point-of-care approach" @default.
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- W3197692076 doi "https://doi.org/10.1136/flgastro-2021-101852" @default.
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