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- W3197844575 abstract "Inflammatory diseases have affected a large proportion of the population worldwide, and inflammation is a major risk factor for several dangerous disease pathologies. The increasing incidence and impact of inflammatory diseases have prompted research into pharmacological strategies to deal with them. Chromolaena odorata is traditionally used as an anti-inflammatory, antipyretic, antioxidant, analgesic, and as a wound-healing agent. Therefore, this review aimed to obtain a comprehensive review of the anti-inflammatory activity of Chromolaena odorata. This review provides evidence in the literature for the anti-inflammatory and analgesic activity of Chromolaena odorata, from 2010 to 2021. Three bibliographic databases were used as primary sources of information (PubMed, ScienceDirect, and Google Scholar). The keywords in this research were Anti-inflammatory, Analgesic and Chromolaena odorata. A total of 7 studies were included in this review according to the required criteria, 3 of which were in vitro studies and 4 in vivo studies.Pharmacological studies reported that Chromolaena odorata was proven to have anti-inflammatory activity by inhibiting NO, NF-κβ, p38 MAPK, IL-1β, TNF-α, suppressed leukocyte cell migration, reduced of edema and Chromolaena odorata also was shown analgesic activity through significantly reduced stomach writhing and reduction pain sensation in rats. This review explains the potential importance of Chromolaena odorata as a natural anti-inflammatory and analgesic." @default.
- W3197844575 created "2021-09-13" @default.
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- W3197844575 date "2021-09-30" @default.
- W3197844575 modified "2023-09-26" @default.
- W3197844575 title "Anti-Inflammatory and Analgesic Potential of Chromolaena odorata: A Review" @default.
- W3197844575 doi "https://doi.org/10.47760/ijpsm.2021.v06i09.002" @default.
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