Matches in SemOpenAlex for { <https://semopenalex.org/work/W3197994239> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W3197994239 abstract "ABSTRACT Aldehydes are a class of chemicals with many industrial uses. Several aldehydes are responsible for flavors and fragrances present in plants, but aldehydes are not known to accumulate in most natural microorganisms. In many cases, microbial production of aldehydes presents an attractive alternative to extraction from plants or chemical synthesis. During the past 2 decades, a variety of aldehyde biosynthetic enzymes have undergone detailed characterization. Although metabolic pathways that result in alcohol synthesis via aldehyde intermediates were long known, only recent investigations in model microbes such as Escherichia coli have succeeded in minimizing the rapid endogenous conversion of aldehydes into their corresponding alcohols. Such efforts have provided a foundation for microbial aldehyde synthesis and broader utilization of aldehydes as intermediates for other synthetically challenging biochemical classes. However, aldehyde toxicity imposes a practical limit on achievable aldehyde titers and remains an issue of academic and commercial interest. In this minireview, we summarize published efforts of microbial engineering for aldehyde synthesis, with an emphasis on de novo synthesis, engineered aldehyde accumulation in E. coli, and the challenge of aldehyde toxicity." @default.
- W3197994239 created "2021-09-13" @default.
- W3197994239 creator A5005731990 @default.
- W3197994239 creator A5061341492 @default.
- W3197994239 date "2015-01-01" @default.
- W3197994239 modified "2023-09-26" @default.
- W3197994239 title "Microbial Engineering for Aldehyde Synthesis" @default.
- W3197994239 cites W1883110779 @default.
- W3197994239 cites W1983595497 @default.
- W3197994239 cites W2005512004 @default.
- W3197994239 cites W2013587011 @default.
- W3197994239 cites W2154402996 @default.
- W3197994239 cites W2170689654 @default.
- W3197994239 cites W2426823810 @default.
- W3197994239 hasPublicationYear "2015" @default.
- W3197994239 type Work @default.
- W3197994239 sameAs 3197994239 @default.
- W3197994239 citedByCount "0" @default.
- W3197994239 crossrefType "journal-article" @default.
- W3197994239 hasAuthorship W3197994239A5005731990 @default.
- W3197994239 hasAuthorship W3197994239A5061341492 @default.
- W3197994239 hasConcept C161790260 @default.
- W3197994239 hasConcept C178790620 @default.
- W3197994239 hasConcept C181199279 @default.
- W3197994239 hasConcept C185592680 @default.
- W3197994239 hasConcept C25747580 @default.
- W3197994239 hasConcept C2779825165 @default.
- W3197994239 hasConcept C6350086 @default.
- W3197994239 hasConceptScore W3197994239C161790260 @default.
- W3197994239 hasConceptScore W3197994239C178790620 @default.
- W3197994239 hasConceptScore W3197994239C181199279 @default.
- W3197994239 hasConceptScore W3197994239C185592680 @default.
- W3197994239 hasConceptScore W3197994239C25747580 @default.
- W3197994239 hasConceptScore W3197994239C2779825165 @default.
- W3197994239 hasConceptScore W3197994239C6350086 @default.
- W3197994239 hasLocation W31979942391 @default.
- W3197994239 hasOpenAccess W3197994239 @default.
- W3197994239 hasPrimaryLocation W31979942391 @default.
- W3197994239 hasRelatedWork W1902843011 @default.
- W3197994239 hasRelatedWork W1963925924 @default.
- W3197994239 hasRelatedWork W2883691989 @default.
- W3197994239 hasRelatedWork W2949230437 @default.
- W3197994239 hasRelatedWork W2951067737 @default.
- W3197994239 hasRelatedWork W2951842385 @default.
- W3197994239 hasRelatedWork W2953140513 @default.
- W3197994239 hasRelatedWork W2953211359 @default.
- W3197994239 hasRelatedWork W2959809730 @default.
- W3197994239 hasRelatedWork W2967636681 @default.
- W3197994239 hasRelatedWork W2981120807 @default.
- W3197994239 hasRelatedWork W3081886499 @default.
- W3197994239 hasRelatedWork W3086326528 @default.
- W3197994239 hasRelatedWork W3088531306 @default.
- W3197994239 hasRelatedWork W3110777803 @default.
- W3197994239 hasRelatedWork W3157229957 @default.
- W3197994239 hasRelatedWork W3159834490 @default.
- W3197994239 hasRelatedWork W3184794071 @default.
- W3197994239 hasRelatedWork W51977154 @default.
- W3197994239 hasRelatedWork W636119870 @default.
- W3197994239 isParatext "false" @default.
- W3197994239 isRetracted "false" @default.
- W3197994239 magId "3197994239" @default.
- W3197994239 workType "article" @default.