FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3198008317> ?p ?o ?g. }

• W3198008317 endingPage "737452" @default.
• W3198008317 startingPage "737452" @default.
• W3198008317 abstract "Vibriosis, including the luminescent shrimp disease and acute hepatopancreatic necrosis disease (AHPND), with Vibrio harveyi as one of their causative agents, is a major shrimp disease causing huge economic losses in the Philippines, Thailand, Vietnam and other Southeast Asian countries. It is induced through the formation of biofilm as a result of bacterial cell-to-cell communication or quorum sensing (QS). Hence, this mechanism may be used as a target for bioactive compounds in controlling V. harveyi infections in shrimp. In this study, crude ethanolic extract (CE) and crude alkaloids (CA) from Ikmo ( Piper betle L.), a plant native to Southeast Asia, were observed to significantly ( p < 0.05) inhibit biofilm formation of wild-type strains V. harveyi VH0, VH1 and BAA-1116 in chitosan-coated microtiter plates without inhibiting their growth. Confocal laser scanning microscopy revealed thinner biofilms formed upon treatment with both extracts. Furthermore, both CE and CA significantly ( p < 0.05) inhibited bioluminescence in QS reference strain V. harveyi BAA-1116 and was found to interfere with QS by modulating autoinducer (AI) activities as observed in both phenotypic and gene expression analyses. Both extracts also did not negatively affect shrimp growth and pre-infection mortality rate. Despite the in vitro results however, in vivo analysis showed that only P. betle CE, when supplemented to shrimp feed, protected Penaeus vannamei postlarvae against V. harveyi infection after seven days. These suggest the potential supplementation of shrimp feed with P. betle crude extract as protection against Vibriosis. • Piper betle inhibited biofilm formation of Vibrio harveyi without growth inhibition. • Phenotypic assays showed P. betle modulated AI-1 and AI-2 pathways of V. harveyi QS. • Gene expression analyses revealed specific targets of P. betle on V. harveyi QS. • P. betle crude extract (CE) protected Penaeus vannamei postlarvae from V. harveyi . • P. betle CE may be used as shrimp feed supplement." @default.
• W3198008317 created "2021-09-13" @default.
• W3198008317 creator A5002661064 @default.
• W3198008317 creator A5027084766 @default.
• W3198008317 creator A5036159756 @default.
• W3198008317 creator A5055706990 @default.
• W3198008317 date "2022-01-01" @default.
• W3198008317 modified "2023-10-17" @default.
• W3198008317 title "Piper betle L. leaf extracts inhibit quorum sensing of shrimp pathogen Vibrio harveyi and protect Penaeus vannamei postlarvae against bacterial infection" @default.
• W3198008317 cites W1844237543 @default.
• W3198008317 cites W1845773772 @default.
• W3198008317 cites W1986819402 @default.
• W3198008317 cites W1987142741 @default.
• W3198008317 cites W1989374697 @default.
• W3198008317 cites W1993211893 @default.
• W3198008317 cites W2005653481 @default.
• W3198008317 cites W2009692012 @default.
• W3198008317 cites W2011777161 @default.
• W3198008317 cites W2021794080 @default.
• W3198008317 cites W2031621154 @default.
• W3198008317 cites W2045123850 @default.
• W3198008317 cites W2050492994 @default.
• W3198008317 cites W2052873409 @default.
• W3198008317 cites W2054198232 @default.
• W3198008317 cites W2067856568 @default.
• W3198008317 cites W2076055471 @default.
• W3198008317 cites W2087415918 @default.
• W3198008317 cites W2090412782 @default.
• W3198008317 cites W2100573469 @default.
• W3198008317 cites W2114878490 @default.
• W3198008317 cites W2118742923 @default.
• W3198008317 cites W2122814663 @default.
• W3198008317 cites W2127347791 @default.
• W3198008317 cites W2151722354 @default.
• W3198008317 cites W2177573561 @default.
• W3198008317 cites W2224368181 @default.
• W3198008317 cites W2296423693 @default.
• W3198008317 cites W2341890548 @default.
• W3198008317 cites W2399340417 @default.
• W3198008317 cites W2471348555 @default.
• W3198008317 cites W2508264906 @default.
• W3198008317 cites W2733506632 @default.
• W3198008317 cites W2752137988 @default.
• W3198008317 cites W2753650496 @default.
• W3198008317 cites W2767718510 @default.
• W3198008317 cites W2785480748 @default.
• W3198008317 cites W2789242133 @default.
• W3198008317 cites W2888644635 @default.
• W3198008317 cites W2892173059 @default.
• W3198008317 cites W2913005192 @default.
• W3198008317 cites W2916150064 @default.
• W3198008317 cites W2951084549 @default.
• W3198008317 cites W4252598576 @default.
• W3198008317 doi "https://doi.org/10.1016/j.aquaculture.2021.737452" @default.
• W3198008317 hasPublicationYear "2022" @default.
• W3198008317 type Work @default.
• W3198008317 sameAs 3198008317 @default.
• W3198008317 citedByCount "9" @default.
• W3198008317 countsByYear W31980083172022 @default.
• W3198008317 countsByYear W31980083172023 @default.
• W3198008317 crossrefType "journal-article" @default.
• W3198008317 hasAuthorship W3198008317A5002661064 @default.
• W3198008317 hasAuthorship W3198008317A5027084766 @default.
• W3198008317 hasAuthorship W3198008317A5036159756 @default.
• W3198008317 hasAuthorship W3198008317A5055706990 @default.
• W3198008317 hasBestOaLocation W31980083171 @default.
• W3198008317 hasConcept C118687296 @default.
• W3198008317 hasConcept C2776154503 @default.
• W3198008317 hasConcept C2776460866 @default.
• W3198008317 hasConcept C2776599375 @default.
• W3198008317 hasConcept C2776841996 @default.
• W3198008317 hasConcept C2778160301 @default.
• W3198008317 hasConcept C2781275326 @default.
• W3198008317 hasConcept C505870484 @default.
• W3198008317 hasConcept C523546767 @default.
• W3198008317 hasConcept C54355233 @default.
• W3198008317 hasConcept C58123911 @default.
• W3198008317 hasConcept C86803240 @default.
• W3198008317 hasConcept C89423630 @default.
• W3198008317 hasConcept C95282255 @default.
• W3198008317 hasConceptScore W3198008317C118687296 @default.
• W3198008317 hasConceptScore W3198008317C2776154503 @default.
• W3198008317 hasConceptScore W3198008317C2776460866 @default.
• W3198008317 hasConceptScore W3198008317C2776599375 @default.
• W3198008317 hasConceptScore W3198008317C2776841996 @default.
• W3198008317 hasConceptScore W3198008317C2778160301 @default.
• W3198008317 hasConceptScore W3198008317C2781275326 @default.
• W3198008317 hasConceptScore W3198008317C505870484 @default.
• W3198008317 hasConceptScore W3198008317C523546767 @default.
• W3198008317 hasConceptScore W3198008317C54355233 @default.
• W3198008317 hasConceptScore W3198008317C58123911 @default.
• W3198008317 hasConceptScore W3198008317C86803240 @default.
• W3198008317 hasConceptScore W3198008317C89423630 @default.
• W3198008317 hasConceptScore W3198008317C95282255 @default.
• W3198008317 hasLocation W31980083171 @default.
• W3198008317 hasOpenAccess W3198008317 @default.
• W3198008317 hasPrimaryLocation W31980083171 @default.
• W3198008317 hasRelatedWork W2004625925 @default.

• next