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• W3198104885 abstract "Glioma stem-like cells (GSCs) were first described as a population which may in part be resistant to traditional chemotherapeutic therapies and responsible for tumour regrowth. Knowledge of the underlying metabolic complexity governing GSC growth and function may point to potential differences between GSCs and the tumour bulk which could be harnessed clinically. There is an increasing interest in the direct/indirect targeting or reprogramming of GSC metabolism as a potential novel therapeutic approach in the adjuvant or recurrent setting to help overcome resistance which may be mediated by GSCs. In this review we will discuss stem-like models, interaction between metabolism and GSCs, and potential current and future strategies for overcoming GSC resistance." @default.
• W3198104885 created "2021-09-13" @default.
• W3198104885 creator A5010921216 @default.
• W3198104885 creator A5029877122 @default.
• W3198104885 creator A5034266315 @default.
• W3198104885 creator A5048472425 @default.
• W3198104885 creator A5055042800 @default.
• W3198104885 creator A5064848403 @default.
• W3198104885 date "2021-08-31" @default.
• W3198104885 modified "2023-10-15" @default.
• W3198104885 title "Glioma Stem-Like Cells and Metabolism: Potential for Novel Therapeutic Strategies" @default.
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