Matches in SemOpenAlex for { <https://semopenalex.org/work/W3198174966> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W3198174966 endingPage "2508" @default.
- W3198174966 startingPage "2501" @default.
- W3198174966 abstract "The present study aimed to demonstrate the extent to which the activity of a number of enzymes and genetic variation of β-globin genes were affected in the blood of 65 children patient with β - thalassemia major of both sexes, their ages ranged between ( 2 – 15 ), who registered in the Thalassemia Center at Ibn Al-Atheer Teaching Hospital for Children in the city of Mosul / Iraq and who are continuing treatment, after they were diagnosed by specialist doctors, as well as 30 healthy children of both sexes with same ages of the patients and it was considered as a control group.
 The results showed a significant increase (P≤0.05) in the activity of Alanine transaminase (ALT), Aspartate transaminase (AST), Alkaline phosphatase (ALP), Glucose 6- phosphate dehydrogenase (G6PD) and Adenosine deaminase (ADA) in the serum of treated children patients with β - Thalassaemia major by 73% , 53%, 8%, 9% and 54% respectively, compared with the healthy children group (control group). Also the results showed a significant increase in the activity of G6PD and ADA in the hemolysis of RBC of the same children patients by 7% and 43% compared with control group.
 When determining the genetic variation of the β-globin gene the result which depends on PCR technique did not show any genetic variation in the size of PCR band ,while the result of the sequencing showed variation in the nucleotides and included converted the nucleotide (A) to (C) in position (250) , change nucleotide (T) to (C) in position (426), replacement (C) nucleotide to (A) in position (623), change (G) nucleotide to (A) in position (630) and replacement (T) to (A) in the position (724), also the result detection three Transversion mutation and two transition mutation in β-globin gene in babies with β-thalassemia" @default.
- W3198174966 created "2021-09-13" @default.
- W3198174966 creator A5048249514 @default.
- W3198174966 creator A5049518820 @default.
- W3198174966 creator A5073352462 @default.
- W3198174966 date "2021-08-31" @default.
- W3198174966 modified "2023-09-27" @default.
- W3198174966 title "Enzymatic and Genetic Study in Blood Among Some Children with β – Thalassaemia in Mosul City, Iraq" @default.
- W3198174966 doi "https://doi.org/10.24996/ijs.2021.62.8.2" @default.
- W3198174966 hasPublicationYear "2021" @default.
- W3198174966 type Work @default.
- W3198174966 sameAs 3198174966 @default.
- W3198174966 citedByCount "0" @default.
- W3198174966 crossrefType "journal-article" @default.
- W3198174966 hasAuthorship W3198174966A5048249514 @default.
- W3198174966 hasAuthorship W3198174966A5049518820 @default.
- W3198174966 hasAuthorship W3198174966A5073352462 @default.
- W3198174966 hasBestOaLocation W31981749661 @default.
- W3198174966 hasConcept C104317684 @default.
- W3198174966 hasConcept C126322002 @default.
- W3198174966 hasConcept C160160445 @default.
- W3198174966 hasConcept C181199279 @default.
- W3198174966 hasConcept C2777799968 @default.
- W3198174966 hasConcept C2777940137 @default.
- W3198174966 hasConcept C2778606649 @default.
- W3198174966 hasConcept C2779679107 @default.
- W3198174966 hasConcept C2779902561 @default.
- W3198174966 hasConcept C42407357 @default.
- W3198174966 hasConcept C512185932 @default.
- W3198174966 hasConcept C54355233 @default.
- W3198174966 hasConcept C55493867 @default.
- W3198174966 hasConcept C71924100 @default.
- W3198174966 hasConcept C86803240 @default.
- W3198174966 hasConceptScore W3198174966C104317684 @default.
- W3198174966 hasConceptScore W3198174966C126322002 @default.
- W3198174966 hasConceptScore W3198174966C160160445 @default.
- W3198174966 hasConceptScore W3198174966C181199279 @default.
- W3198174966 hasConceptScore W3198174966C2777799968 @default.
- W3198174966 hasConceptScore W3198174966C2777940137 @default.
- W3198174966 hasConceptScore W3198174966C2778606649 @default.
- W3198174966 hasConceptScore W3198174966C2779679107 @default.
- W3198174966 hasConceptScore W3198174966C2779902561 @default.
- W3198174966 hasConceptScore W3198174966C42407357 @default.
- W3198174966 hasConceptScore W3198174966C512185932 @default.
- W3198174966 hasConceptScore W3198174966C54355233 @default.
- W3198174966 hasConceptScore W3198174966C55493867 @default.
- W3198174966 hasConceptScore W3198174966C71924100 @default.
- W3198174966 hasConceptScore W3198174966C86803240 @default.
- W3198174966 hasLocation W31981749661 @default.
- W3198174966 hasOpenAccess W3198174966 @default.
- W3198174966 hasPrimaryLocation W31981749661 @default.
- W3198174966 hasRelatedWork W1490226871 @default.
- W3198174966 hasRelatedWork W2044096107 @default.
- W3198174966 hasRelatedWork W2103655963 @default.
- W3198174966 hasRelatedWork W2270726089 @default.
- W3198174966 hasRelatedWork W2536878799 @default.
- W3198174966 hasRelatedWork W3171649585 @default.
- W3198174966 hasRelatedWork W3198174966 @default.
- W3198174966 hasRelatedWork W4220908857 @default.
- W3198174966 hasRelatedWork W4367333260 @default.
- W3198174966 hasRelatedWork W3119136269 @default.
- W3198174966 isParatext "false" @default.
- W3198174966 isRetracted "false" @default.
- W3198174966 magId "3198174966" @default.
- W3198174966 workType "article" @default.