Matches in SemOpenAlex for { <https://semopenalex.org/work/W3198472003> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W3198472003 endingPage "112062" @default.
- W3198472003 startingPage "112062" @default.
- W3198472003 abstract "Casein hydrolysate (Pep) is a dispersant for poorly water-soluble drugs and nutraceutical ingredients. However, two types of complexes may be between Pep and poorly water-soluble molecules: those that are (1) dispersed as hydrocolloids in aqueous media with a particle size of 100–500 nm; and (2) not hydrocolloids, as indicated by permeability of the complex through an ultrafiltration (UF) membrane and the fact that the particle size is ambiguous by dynamic light scattering. This study was conducted to clarify the factors that determine the dissolution state of the complexes between poorly water-soluble ingredients and casein hydrolysate. We classified the dissolution state of the complexes between poorly water-soluble ingredients and Pep by the permeability using a UF membrane. Complexes containing larger and more-hydrophobic molecules are hydrocolloids and do not permeate the UF membrane, whereas complexes containing comparatively smaller and less-hydrophobic molecules do permeate the UF membrane. A complex containing indomethacin, which has borderline solubility properties, does not permeate the UF membrane at pH values in which the indomethacin carboxylic acid group is protonated, but it is permeable at pH values in which its carboxylic acid group is deprotonated. Furthermore, we determined the stoichiometry and association constant for the complex between a major peptide in Pep and poorly water-soluble resveratrol (Res) based on fluorescence quenching. We calculated the stoichiometry of Res and PepY to be 2:3 and the association constant to be 2.4 × 107 M−1." @default.
- W3198472003 created "2021-09-13" @default.
- W3198472003 creator A5044194005 @default.
- W3198472003 creator A5061505845 @default.
- W3198472003 creator A5084563844 @default.
- W3198472003 date "2021-12-01" @default.
- W3198472003 modified "2023-09-25" @default.
- W3198472003 title "Dominant factors that determine the dissolution state of complexes between poorly water-soluble ingredients and casein hydrolysate" @default.
- W3198472003 cites W1086812113 @default.
- W3198472003 cites W1964738974 @default.
- W3198472003 cites W1976776496 @default.
- W3198472003 cites W2034710312 @default.
- W3198472003 cites W2050384029 @default.
- W3198472003 cites W2057787758 @default.
- W3198472003 cites W2072818864 @default.
- W3198472003 cites W2074582913 @default.
- W3198472003 cites W2078166953 @default.
- W3198472003 cites W2084146115 @default.
- W3198472003 cites W2084879398 @default.
- W3198472003 cites W2086650411 @default.
- W3198472003 cites W2092900117 @default.
- W3198472003 cites W2093581889 @default.
- W3198472003 cites W2144417922 @default.
- W3198472003 cites W2154587590 @default.
- W3198472003 cites W2345385486 @default.
- W3198472003 cites W2403997972 @default.
- W3198472003 cites W2433205350 @default.
- W3198472003 cites W2795134501 @default.
- W3198472003 cites W2946423640 @default.
- W3198472003 doi "https://doi.org/10.1016/j.colsurfb.2021.112062" @default.
- W3198472003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34492601" @default.
- W3198472003 hasPublicationYear "2021" @default.
- W3198472003 type Work @default.
- W3198472003 sameAs 3198472003 @default.
- W3198472003 citedByCount "0" @default.
- W3198472003 crossrefType "journal-article" @default.
- W3198472003 hasAuthorship W3198472003A5044194005 @default.
- W3198472003 hasAuthorship W3198472003A5061505845 @default.
- W3198472003 hasAuthorship W3198472003A5084563844 @default.
- W3198472003 hasConcept C155574463 @default.
- W3198472003 hasConcept C178790620 @default.
- W3198472003 hasConcept C184651966 @default.
- W3198472003 hasConcept C185592680 @default.
- W3198472003 hasConcept C2776142715 @default.
- W3198472003 hasConcept C28800991 @default.
- W3198472003 hasConcept C41625074 @default.
- W3198472003 hasConcept C43617362 @default.
- W3198472003 hasConcept C50670333 @default.
- W3198472003 hasConcept C50817676 @default.
- W3198472003 hasConcept C55493867 @default.
- W3198472003 hasConcept C88380143 @default.
- W3198472003 hasConcept C94412978 @default.
- W3198472003 hasConceptScore W3198472003C155574463 @default.
- W3198472003 hasConceptScore W3198472003C178790620 @default.
- W3198472003 hasConceptScore W3198472003C184651966 @default.
- W3198472003 hasConceptScore W3198472003C185592680 @default.
- W3198472003 hasConceptScore W3198472003C2776142715 @default.
- W3198472003 hasConceptScore W3198472003C28800991 @default.
- W3198472003 hasConceptScore W3198472003C41625074 @default.
- W3198472003 hasConceptScore W3198472003C43617362 @default.
- W3198472003 hasConceptScore W3198472003C50670333 @default.
- W3198472003 hasConceptScore W3198472003C50817676 @default.
- W3198472003 hasConceptScore W3198472003C55493867 @default.
- W3198472003 hasConceptScore W3198472003C88380143 @default.
- W3198472003 hasConceptScore W3198472003C94412978 @default.
- W3198472003 hasFunder F4320325855 @default.
- W3198472003 hasFunder F4320334764 @default.
- W3198472003 hasLocation W31984720031 @default.
- W3198472003 hasOpenAccess W3198472003 @default.
- W3198472003 hasPrimaryLocation W31984720031 @default.
- W3198472003 hasRelatedWork W1967524356 @default.
- W3198472003 hasRelatedWork W2023011915 @default.
- W3198472003 hasRelatedWork W2055315753 @default.
- W3198472003 hasRelatedWork W2074074972 @default.
- W3198472003 hasRelatedWork W2093646936 @default.
- W3198472003 hasRelatedWork W2363137987 @default.
- W3198472003 hasRelatedWork W2383147820 @default.
- W3198472003 hasRelatedWork W2908799665 @default.
- W3198472003 hasRelatedWork W2913831029 @default.
- W3198472003 hasRelatedWork W4313826511 @default.
- W3198472003 hasVolume "208" @default.
- W3198472003 isParatext "false" @default.
- W3198472003 isRetracted "false" @default.
- W3198472003 magId "3198472003" @default.
- W3198472003 workType "article" @default.