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- W3198536644 abstract "<h2>ABSTRACT</h2><h3>Background</h3> Timely identification and management of sepsis in surgical patients is crucial, and transfer status may delay optimal treatment of these patients. The objective of this study was to compare in-house and 90-day mortality between patients primarily admitted or transferred into the surgical ICU (SICU) at a tertiary referral center. <h3>Material and methods</h3> All patients admitted to the SICU with a diagnosis of sepsis (Sepsis III) were reviewed at a single institution between 2014 to 2019 (<i>n</i> = 1489). Demographics, comorbidities, and sepsis presentation were compared between transferred (<i>n</i> = 696) and primary patients (<i>n</i> = 793). Primary outcomes evaluated were in-house and 90 day mortality in an unmatched and propensity score matched cohorts. A <i>P</i> value < 0.05 was considered statistically significant. <h3>Results</h3> Transfer patients were more likely to have obesity (60% <i>versus</i> 49%, <i>P</i> < 0.005), a higher median SOFA (6 (4-8) <i>versus</i> 5 (3-8), <i>P</i> = 0.007), and require vasopressors on admission (42% <i>versus</i> 35%, <i>P</i> = 0.004). Compared to primary patients, transfer patients exhibited higher rates of respiratory failure (76% <i>versus</i> 69%, <i>P</i> = 0.003), in-house (30% <i>versus</i> 17%, <i>P</i> < 0.005), and 90 day mortality (36% <i>versus</i> 24%, <i>P</i> < 0.005). After matching, transferred patients were associated with 75% and 83% increased odds of in-house and 90 day mortality after controlling for age, sex, race, comorbidities, BMI, and sepsis severity. <h3>Conclusions</h3> Transfer status is associated with an over 80% increase in the odds of 90 day mortality for patients admitted to the SICU with sepsis. Aggressive patient identification and earlier transfer of those at higher risk of death may reduce this effect." @default.
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- W3198536644 date "2021-12-01" @default.
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- W3198536644 title "Transfer Status and 90-Day Mortality in ICU Patients with Sepsis: A Propensity Matched Analysis" @default.
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- W3198536644 doi "https://doi.org/10.1016/j.jss.2021.07.014" @default.
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