Matches in SemOpenAlex for { <https://semopenalex.org/work/W3198688051> ?p ?o ?g. }
- W3198688051 endingPage "111976" @default.
- W3198688051 startingPage "111976" @default.
- W3198688051 abstract "Growing epidemiological evidence suggests that air pollution may increase the risk of cognitive decline and neurodegenerative disease. A hallmark of neurodegeneration and an important diagnostic biomarker is volume reduction of a key brain structure, the hippocampus. We aimed to investigate the possibility that outdoor air nitrogen dioxide (NO2) and particulate matter with diameter ≤2.5 μm (PM2.5) and ≤10 μm (PM10) adversely affect hippocampal volume, through a meta-analysis. We considered studies that assessed the relation between outdoor air pollution and hippocampal volume by structural magnetic resonance imaging in adults and children, searching in Pubmed and Scopus databases from inception through July 13, 2021. For inclusion, studies had to report the correlation coefficient along with its standard error or 95% confidence interval (CI) between air pollutant exposure and hippocampal volume, to use standard space for neuroimages, and to consider at least age, sex and intracranial volume as covariates or effect modifiers. We meta-analyzed the data with a random-effects model, considering separately adult and child populations. We retrieved four eligible studies in adults and two in children. In adults, the pooled summary β regression coefficients of the association of PM2.5, PM10 and NO2 with hippocampal volume showed respectively a stronger association (summary β -7.59, 95% CI -14.08 to -1.11), a weaker association (summary β -2.02, 95% CI -4.50 to 0.47), and no association (summary β -0.44, 95% CI -1.27 to 0.40). The two studies available for children, both carried out in preadolescents, did not show an association between PM2.5 and hippocampal volume. The inverse association between PM2.5 and hippocampal volume in adults appeared to be stronger at higher mean PM2.5 levels. Our results suggest that outdoor PM2.5 and less strongly PM10 could adversely affect hippocampal volume in adults, a phenomenon that may explain why air pollution has been related to memory loss, cognitive decline, and dementia." @default.
- W3198688051 created "2021-09-13" @default.
- W3198688051 creator A5019308808 @default.
- W3198688051 creator A5053903866 @default.
- W3198688051 creator A5071969063 @default.
- W3198688051 creator A5072128855 @default.
- W3198688051 creator A5077899672 @default.
- W3198688051 creator A5082749233 @default.
- W3198688051 date "2022-03-01" @default.
- W3198688051 modified "2023-10-13" @default.
- W3198688051 title "The association between air pollutants and hippocampal volume from magnetic resonance imaging: A systematic review and meta-analysis" @default.
- W3198688051 cites W1968591792 @default.
- W3198688051 cites W1970684162 @default.
- W3198688051 cites W1992013962 @default.
- W3198688051 cites W1997147328 @default.
- W3198688051 cites W2004293194 @default.
- W3198688051 cites W2006096283 @default.
- W3198688051 cites W2044367669 @default.
- W3198688051 cites W2053919734 @default.
- W3198688051 cites W2062970435 @default.
- W3198688051 cites W2113081633 @default.
- W3198688051 cites W2117738566 @default.
- W3198688051 cites W2128523626 @default.
- W3198688051 cites W2130831435 @default.
- W3198688051 cites W2133862271 @default.
- W3198688051 cites W2135772291 @default.
- W3198688051 cites W2142367912 @default.
- W3198688051 cites W2168283959 @default.
- W3198688051 cites W2214659052 @default.
- W3198688051 cites W2326368503 @default.
- W3198688051 cites W2423252051 @default.
- W3198688051 cites W2499884006 @default.
- W3198688051 cites W2522922482 @default.
- W3198688051 cites W2552124963 @default.
- W3198688051 cites W2570634615 @default.
- W3198688051 cites W2611917744 @default.
- W3198688051 cites W2792469299 @default.
- W3198688051 cites W2793482394 @default.
- W3198688051 cites W2809162967 @default.
- W3198688051 cites W2884548474 @default.
- W3198688051 cites W2885372571 @default.
- W3198688051 cites W2895486342 @default.
- W3198688051 cites W2898890166 @default.
- W3198688051 cites W2941058628 @default.
- W3198688051 cites W2950427619 @default.
- W3198688051 cites W2950613646 @default.
- W3198688051 cites W2967875323 @default.
- W3198688051 cites W2972010641 @default.
- W3198688051 cites W2989892704 @default.
- W3198688051 cites W3002397313 @default.
- W3198688051 cites W3008287292 @default.
- W3198688051 cites W3009241720 @default.
- W3198688051 cites W3010933837 @default.
- W3198688051 cites W3011786716 @default.
- W3198688051 cites W3026867661 @default.
- W3198688051 cites W3035097473 @default.
- W3198688051 cites W3041584462 @default.
- W3198688051 cites W3046275966 @default.
- W3198688051 cites W3085973574 @default.
- W3198688051 cites W3090777620 @default.
- W3198688051 cites W3097909932 @default.
- W3198688051 cites W3103772440 @default.
- W3198688051 cites W3109209068 @default.
- W3198688051 cites W3109937594 @default.
- W3198688051 cites W3111145749 @default.
- W3198688051 cites W3117238485 @default.
- W3198688051 cites W3125300795 @default.
- W3198688051 cites W3132665809 @default.
- W3198688051 cites W3145606882 @default.
- W3198688051 cites W3153689303 @default.
- W3198688051 cites W3157319305 @default.
- W3198688051 cites W3164639918 @default.
- W3198688051 cites W3165984234 @default.
- W3198688051 cites W3177362747 @default.
- W3198688051 doi "https://doi.org/10.1016/j.envres.2021.111976" @default.
- W3198688051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34478724" @default.
- W3198688051 hasPublicationYear "2022" @default.
- W3198688051 type Work @default.
- W3198688051 sameAs 3198688051 @default.
- W3198688051 citedByCount "16" @default.
- W3198688051 countsByYear W31986880512022 @default.
- W3198688051 countsByYear W31986880512023 @default.
- W3198688051 crossrefType "journal-article" @default.
- W3198688051 hasAuthorship W3198688051A5019308808 @default.
- W3198688051 hasAuthorship W3198688051A5053903866 @default.
- W3198688051 hasAuthorship W3198688051A5071969063 @default.
- W3198688051 hasAuthorship W3198688051A5072128855 @default.
- W3198688051 hasAuthorship W3198688051A5077899672 @default.
- W3198688051 hasAuthorship W3198688051A5082749233 @default.
- W3198688051 hasBestOaLocation W31986880511 @default.
- W3198688051 hasConcept C107130276 @default.
- W3198688051 hasConcept C126322002 @default.
- W3198688051 hasConcept C126838900 @default.
- W3198688051 hasConcept C143409427 @default.
- W3198688051 hasConcept C148762608 @default.
- W3198688051 hasConcept C185592680 @default.
- W3198688051 hasConcept C2781161787 @default.
- W3198688051 hasConcept C2781197716 @default.