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- W3198709747 startingPage "132" @default.
- W3198709747 abstract "Tumor mass and its microenvironment alter host immune system in various ways to promote tumor growth. One of the modifications is evasion of immune surveillance by augmenting the number of Tregs in tumor vicinity. Elevated levels of Tregs are seen in peripheral circulation and tumor tissue of cancer patients. Cancer cells release several chemokines to attract Tregs in tumor-site. Infiltration of Tregs has clinical significance because being immunosuppressive infiltrating Tregs suppress other immune cells making the tumor microenvironment favorable for tumor growth. On the other hand, infiltrating Tregs show metabolic alteration in tumor microenvironment which allows their selective survival over the others. Persistence of Tregs in the tumor microenvironment and subsequent immunosuppression makes Tregs a potential therapeutic obstacle and the reason behind the failure of immunotherapy. In this review, we emphasize the recent development in the metabolic adaptation of tumor-infiltrating Tregs and the therapeutic approaches to boost immunity against cancer." @default.
- W3198709747 created "2021-09-13" @default.
- W3198709747 creator A5018004744 @default.
- W3198709747 creator A5021647592 @default.
- W3198709747 creator A5085821052 @default.
- W3198709747 date "2021-01-01" @default.
- W3198709747 modified "2023-10-01" @default.
- W3198709747 title "Tumor-infiltrating T-regulatory cells adapt to altered metabolism to promote tumor-immune escape" @default.
- W3198709747 cites W1484130254 @default.
- W3198709747 cites W1488390118 @default.
- W3198709747 cites W1554690759 @default.
- W3198709747 cites W1575688729 @default.
- W3198709747 cites W1598843567 @default.
- W3198709747 cites W1630171124 @default.
- W3198709747 cites W1705652018 @default.
- W3198709747 cites W1774346723 @default.
- W3198709747 cites W1918238463 @default.
- W3198709747 cites W1981859401 @default.
- W3198709747 cites W1984543828 @default.
- W3198709747 cites W1985010149 @default.
- W3198709747 cites W1993023349 @default.
- W3198709747 cites W1995068577 @default.
- W3198709747 cites W1996365670 @default.
- W3198709747 cites W2002726823 @default.
- W3198709747 cites W2003076820 @default.
- W3198709747 cites W2007172990 @default.
- W3198709747 cites W2010260569 @default.
- W3198709747 cites W2015587858 @default.
- W3198709747 cites W2020996229 @default.
- W3198709747 cites W2021928123 @default.
- W3198709747 cites W2022996006 @default.
- W3198709747 cites W2023300506 @default.
- W3198709747 cites W2035876629 @default.
- W3198709747 cites W2036296436 @default.
- W3198709747 cites W2036383793 @default.
- W3198709747 cites W2037034595 @default.
- W3198709747 cites W2046972425 @default.
- W3198709747 cites W2048152449 @default.
- W3198709747 cites W2049636267 @default.
- W3198709747 cites W2051940153 @default.
- W3198709747 cites W2057965214 @default.
- W3198709747 cites W2059377172 @default.
- W3198709747 cites W2059893951 @default.
- W3198709747 cites W2060140038 @default.
- W3198709747 cites W2060185417 @default.
- W3198709747 cites W2065948425 @default.
- W3198709747 cites W2072613763 @default.
- W3198709747 cites W2073747749 @default.
- W3198709747 cites W2079999658 @default.
- W3198709747 cites W2085182377 @default.
- W3198709747 cites W2085325381 @default.
- W3198709747 cites W2085388633 @default.
- W3198709747 cites W2088910163 @default.
- W3198709747 cites W2089846992 @default.
- W3198709747 cites W2091835252 @default.
- W3198709747 cites W2091918246 @default.
- W3198709747 cites W2095209881 @default.
- W3198709747 cites W2095434093 @default.
- W3198709747 cites W2097259163 @default.
- W3198709747 cites W2098958083 @default.
- W3198709747 cites W2100039832 @default.
- W3198709747 cites W2111130690 @default.
- W3198709747 cites W2115094537 @default.
- W3198709747 cites W2115096627 @default.
- W3198709747 cites W2116576993 @default.
- W3198709747 cites W2117973220 @default.
- W3198709747 cites W2120010406 @default.
- W3198709747 cites W2120233660 @default.
- W3198709747 cites W2121626779 @default.
- W3198709747 cites W2126268734 @default.
- W3198709747 cites W2128334384 @default.
- W3198709747 cites W2128792706 @default.
- W3198709747 cites W2140907689 @default.
- W3198709747 cites W2141722144 @default.
- W3198709747 cites W2142644858 @default.
- W3198709747 cites W2145453174 @default.
- W3198709747 cites W2146791037 @default.
- W3198709747 cites W2148226248 @default.
- W3198709747 cites W2150678612 @default.
- W3198709747 cites W2154224978 @default.
- W3198709747 cites W2154560517 @default.
- W3198709747 cites W2157886452 @default.
- W3198709747 cites W2160551785 @default.
- W3198709747 cites W2166438464 @default.
- W3198709747 cites W2166484453 @default.
- W3198709747 cites W2167054695 @default.
- W3198709747 cites W2168631000 @default.
- W3198709747 cites W2169083371 @default.
- W3198709747 cites W2263759961 @default.
- W3198709747 cites W2266688184 @default.
- W3198709747 cites W2273660998 @default.
- W3198709747 cites W2322378248 @default.
- W3198709747 cites W2335687927 @default.
- W3198709747 cites W2395444360 @default.
- W3198709747 cites W2395780124 @default.
- W3198709747 cites W2403976714 @default.
- W3198709747 cites W2412718576 @default.
- W3198709747 cites W2518249323 @default.