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- W3199029907 abstract "In keeping with the theme of this Edition of Burger's Medicinal Chemistry and Drug Discovery as a drug hunter's guide, six case histories of anti-infective drug discovery are presented. These were independently written by the project leaders or inventive authors and include (i) structure-based design of mannoside FimH bacterial lectin antagonists, (ii) phenotypic screen antimalarial clinical candidate (+)-SJ733, (iii) discovery and repurposing of Auranofin as a broad-spectrum anti-parasitic agent, (iv) discovery and development of antimalarial UCT943, a back-up candidate to MMV048, (v) medicinal chemistry of broad-spectrum aureobasidin-derived antifungals, and (vi) lessons learned advancing lantibiotics into preclinical and clinical development." @default.
- W3199029907 created "2021-09-27" @default.
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- W3199029907 date "2021-04-30" @default.
- W3199029907 modified "2023-09-26" @default.
- W3199029907 title "Anti‐Infective Case Histories" @default.
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