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- W3199087843 abstract "Routine single-sample haplotype-resolved assembly remains an unresolved problem. Here we describe a new algorithm that combines PacBio HiFi reads and Hi-C chromatin interaction data to produce a haplotype-resolved assembly without the sequencing of parents. Applied to human and other vertebrate samples, our algorithm consistently outperforms existing single-sample assembly pipelines and generates assemblies of comparable quality to the best pedigree-based assemblies." @default.
- W3199087843 created "2021-09-27" @default.
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- W3199087843 date "2021-09-10" @default.
- W3199087843 modified "2023-09-23" @default.
- W3199087843 title "Robust haplotype-resolved assembly of diploid individuals without parental data" @default.
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- W3199087843 doi "https://doi.org/10.48550/arxiv.2109.04785" @default.
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