Matches in SemOpenAlex for { <https://semopenalex.org/work/W3199112118> ?p ?o ?g. }
- W3199112118 abstract "Abstract To identify the prevalence and risk factors for primary Epstein–Barr virus (EBV) infection in human immunodeficiency virus (HIV)-1-positive adult treatment-naïve patients between January 2018 and December 2019 in a state of the Brazilian Amazon region. A total of 268 HIV-1 positive patients and 65 blood donors participated in the study. Epidemiological data were obtained from medical records and through a designed questionnaire. EBV infection was screened by the semiquantitative detection of anti-viral capsid antigen (VCA) EBV IgM and IgG, followed by molecular detection of the EBNA-3C gene. The plasma viral loads of HIV-1 and EBV were quantified using a commercial kit. The prevalence of primary coinfection was 7.12%. The associated risk factors were education level, family income, history of illicit drug use and sexually transmitted infections, homosexual contact and condom nonuse. Approximately 58.5% had late initiation of highly active antiretroviral therapy, which influenced the risk of HIV-EBV 1/2 multiple infection (odds ratio (OR): 4.76; 95% CI 1.51–15.04) and symptom development (p = 0.004). HIV viral load was associated with patient age (OR: 2.04; 95% CI 2.01–2.07; p = 0.026) and duration of illicit drug use (OR: 1.57; 95% CI 1.12–2.22; p = 0.0548). EBV viral load was associated with younger age (OR: 0.82; 95% CI 0.79–1.03; p = 0.0579). The replication of both viruses was associated with symptom development (HIV = OR: 2.06; 95% CI 1.22–3.50; p = 0.0073; EBV = OR: 8.81; 95% CI 1–10; p = 0.0447). The prevalence of HIV/EBV coinfection was lower than that observed in other studies, and social vulnerability and promiscuous sexual behavior were associated risk factors. A long time of HIV-1 infection, without therapy, influenced the risk of coinfection and disease progression. The viral loads of both viruses may be associated with some epidemiological aspects of the population." @default.
- W3199112118 created "2021-09-27" @default.
- W3199112118 creator A5005519668 @default.
- W3199112118 creator A5010819698 @default.
- W3199112118 creator A5011317140 @default.
- W3199112118 creator A5020263730 @default.
- W3199112118 creator A5027399041 @default.
- W3199112118 creator A5027988649 @default.
- W3199112118 creator A5038413995 @default.
- W3199112118 creator A5045834125 @default.
- W3199112118 creator A5057439597 @default.
- W3199112118 creator A5059636523 @default.
- W3199112118 creator A5067056910 @default.
- W3199112118 creator A5090478535 @default.
- W3199112118 date "2021-09-16" @default.
- W3199112118 modified "2023-09-25" @default.
- W3199112118 title "Epidemiological risk factors associated with primary infection by Epstein–Barr virus in HIV-1-positive subjects in the Brazilian Amazon region" @default.
- W3199112118 cites W1514170689 @default.
- W3199112118 cites W1531490664 @default.
- W3199112118 cites W1549996779 @default.
- W3199112118 cites W1565629859 @default.
- W3199112118 cites W161080440 @default.
- W3199112118 cites W1650356683 @default.
- W3199112118 cites W1935176174 @default.
- W3199112118 cites W1946498671 @default.
- W3199112118 cites W1952663953 @default.
- W3199112118 cites W1968126496 @default.
- W3199112118 cites W1968942175 @default.
- W3199112118 cites W1983325003 @default.
- W3199112118 cites W1983672108 @default.
- W3199112118 cites W1984162123 @default.
- W3199112118 cites W1985473332 @default.
- W3199112118 cites W2001399893 @default.
- W3199112118 cites W2009392010 @default.
- W3199112118 cites W2027527568 @default.
- W3199112118 cites W2033299452 @default.
- W3199112118 cites W2039083061 @default.
- W3199112118 cites W2047948412 @default.
- W3199112118 cites W2049352535 @default.
- W3199112118 cites W2051840817 @default.
- W3199112118 cites W2056301053 @default.
- W3199112118 cites W2056932865 @default.
- W3199112118 cites W2059515606 @default.
- W3199112118 cites W2062549647 @default.
- W3199112118 cites W2076551782 @default.
- W3199112118 cites W2078585226 @default.
- W3199112118 cites W2080183947 @default.
- W3199112118 cites W2087110294 @default.
- W3199112118 cites W2094341017 @default.
- W3199112118 cites W2098255284 @default.
- W3199112118 cites W2101307264 @default.
- W3199112118 cites W2103534360 @default.
- W3199112118 cites W2105505081 @default.
- W3199112118 cites W2106484544 @default.
- W3199112118 cites W2108120404 @default.
- W3199112118 cites W2113067927 @default.
- W3199112118 cites W2115476494 @default.
- W3199112118 cites W2116181186 @default.
- W3199112118 cites W2116240179 @default.
- W3199112118 cites W2116688508 @default.
- W3199112118 cites W2119869627 @default.
- W3199112118 cites W2120421639 @default.
- W3199112118 cites W2123027218 @default.
- W3199112118 cites W2125417662 @default.
- W3199112118 cites W2127016811 @default.
- W3199112118 cites W2132178991 @default.
- W3199112118 cites W2138694347 @default.
- W3199112118 cites W2139544488 @default.
- W3199112118 cites W2144164162 @default.
- W3199112118 cites W2144284788 @default.
- W3199112118 cites W2145513855 @default.
- W3199112118 cites W2155384057 @default.
- W3199112118 cites W2157159941 @default.
- W3199112118 cites W2158114211 @default.
- W3199112118 cites W2158707356 @default.
- W3199112118 cites W2162170531 @default.
- W3199112118 cites W2162387779 @default.
- W3199112118 cites W2164080064 @default.
- W3199112118 cites W2171817791 @default.
- W3199112118 cites W2179727796 @default.
- W3199112118 cites W2209647006 @default.
- W3199112118 cites W2268713379 @default.
- W3199112118 cites W2318059450 @default.
- W3199112118 cites W2333411325 @default.
- W3199112118 cites W2343046980 @default.
- W3199112118 cites W2507369261 @default.
- W3199112118 cites W2510924939 @default.
- W3199112118 cites W2522939951 @default.
- W3199112118 cites W2526084172 @default.
- W3199112118 cites W2530475726 @default.
- W3199112118 cites W2567707807 @default.
- W3199112118 cites W2605463690 @default.
- W3199112118 cites W2606823726 @default.
- W3199112118 cites W2607418663 @default.
- W3199112118 cites W2615090808 @default.
- W3199112118 cites W2620895512 @default.
- W3199112118 cites W2678493461 @default.
- W3199112118 cites W2742681205 @default.
- W3199112118 cites W2746221158 @default.
- W3199112118 cites W2768519606 @default.