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• W3199202471 abstract "It is important to conduct taxonomy research on the bacteria kingdom for deeper understanding, which can utilize the conserved genes, 16s rRNA, protein domain, and so on. Among them, the methods based on the protein domain has a direct relationship with phenotype. However, these methods still lack analysis of their biological significance, models evaluation and the comparison of taxonomy results. To this end, we propose a complete framework to standardize the process for taxonomy problem based on the protein functional domain. By applying it to bacteria kingdom and comparing the results with the NCBI taxonomy, we point out the most appropriate method in each step of the framework and evaluate models according to the biological significance. Finally, taxonomy suggestions and recommendations are proposed based on the phylogenetic tree generated by the framework with the most appropriate combination." @default.
• W3199202471 created "2021-09-27" @default.
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• W3199202471 date "2021-09-20" @default.
• W3199202471 modified "2023-10-16" @default.
• W3199202471 title "Taxonomy Analysis in Bacteria Kingdom based on Protein Domain: A Comparison Study" @default.
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• W3199202471 doi "https://doi.org/10.1101/2021.09.17.460715" @default.
• W3199202471 hasPublicationYear "2021" @default.
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