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- W3199280123 abstract "A wide body of literature suggests that transcranial direct current stimulation (tDCS) administered over the prefrontal cortex can improve executive function - including decision-making and inhibitory control - in healthy young adults. However, the effects of tDCS in older adults are largely unknown. Here, using a double-blind, sham-controlled approach, changes in a combined perceptual decision-making and inhibitory control task were assessed before and after the application of tDCS (1 mA, 20 minute) targeting the right inferior frontal gyrus (rIFG) or pre-supplementary motor area (preSMA) in 42 young (18-34 years) and 41 older (60-80 years) healthy adults. Compared to sham stimulation, anodal tDCS over the preSMA improved decision-making speed for both age groups. Furthermore, the inhibitory control performance of older and younger adults was improved by preSMA and rIFG stimulation, respectively. This study provides evidence that tDCS can improve both perceptual decision-making and inhibitory control in healthy older adults, with the causal role of the preSMA and rIFG regions in cognitive control appearing to vary as a function of healthy ageing." @default.
- W3199280123 created "2021-09-27" @default.
- W3199280123 creator A5027436084 @default.
- W3199280123 creator A5029397426 @default.
- W3199280123 creator A5061721952 @default.
- W3199280123 creator A5073013659 @default.
- W3199280123 date "2022-01-01" @default.
- W3199280123 modified "2023-10-17" @default.
- W3199280123 title "Influence of tDCS over right inferior frontal gyrus and pre-supplementary motor area on perceptual decision-making and response inhibition: A healthy ageing perspective" @default.
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- W3199280123 doi "https://doi.org/10.1016/j.neurobiolaging.2021.09.014" @default.
- W3199280123 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34634749" @default.
- W3199280123 hasPublicationYear "2022" @default.
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