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• W3199286871 abstract "Uridine diphosphate glucosyltransferases (UGTs), which are phase II detoxification enzymes, are found in various organisms. These enzymes play an important role in the detoxification mechanisms of plant allelopathy and in insects. Artemisia vulgaris L. (Asterales: Asteraceae: Artemisia) essential oil has strong contact toxicity to Tribolium castaneum Herbst (Coleoptera: Tenebrionidae) larvae. However, the effect of A. vulgaris essential oil on UGTs is unclear. In this study, A. vulgaris essential oil was shown to significantly induce the expression of the TcUgt86Dg transcript. Furthermore, treatment of TcUgt86Dg-silenced individuals with A. vulgaris essential oil resulted in higher mortality than for the control individuals, indicating that TcUgt86Dg is involved in detoxification of A. vulgaris essential oil in T. castaneum. The developmental expression profile showed that the expression of TcUgt86Dg in late adults was higher than in other developmental stages. Furthermore, the expression profile in adult tissues revealed higher expression of TcUgt86Dg in the head, antenna, fat body, and accessory gland than in other tissues. These data show that TcUgt86Dg may be involved in the metabolism of exogenous toxins by T. castaneum; thus, our results have elucidated one possible mechanism of resistance to A. vulgaris essential oil and provide a theoretical basis for a control scheme for T. castaneum." @default.
• W3199286871 created "2021-09-27" @default.
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• W3199286871 date "2021-09-21" @default.
• W3199286871 modified "2023-10-16" @default.
• W3199286871 title "Knockdown of Uridine Diphosphate Glucosyltransferase 86Dg Enhances Susceptibility of <i>Tribolium castaneum</i> (Coleoptera: Tenebrionidae) to <i>Artemisia vulgaris</i> (Asterales: Asteraceae) Essential Oil" @default.
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• W3199286871 doi "https://doi.org/10.1093/jee/toab182" @default.
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