Matches in SemOpenAlex for { <https://semopenalex.org/work/W3199300507> ?p ?o ?g. }
- W3199300507 abstract "Prevalence of sarcopenia has increased in patients with type 2 diabetes. The influence of glucose-lowering drugs on muscles in these patients remains unclear. We aimed to investigate the association between muscle mass/function and glucose-lowering drugs. Data of 1042 hospitalized patients with type 2 diabetes were included in this retrospective, cross-sectional study. All the patients had stable hypoglycemic therapy in the last 3 months, and performed bioelectrical impedance analysis, grip strength, and gait speed tests on admission. Skeletal muscle index [6.81 (95% CI 6.67, 6.94) vs. 7.17 (7.09, 7.24) kg/m2], handgrip strength [23.41 (22.24, 24.58) vs. 26.93 (26.33, 27.54) kg], and gait speed [1.19 (1.15, 1.22) vs. 1.27 (1.25, 1.28) m/s] decreased in patients using acarbose compared with the others (all p < 0.001). Gait speed and skeletal muscle index remained lower in patients using acarbose compared to their matched patients in propensity score matching (p = 0.036 and 0.010, respectively). Among drug-naïve patients and patients using insulin, metformin, sulfonylureas, or acarbose monotherapy, the acarbose group had lowest skeletal muscle index and handgrip strength [6.81 (6.52, 7.11) kg/m2 and 22.54 (19.28, 25.79) kg, p = 0.028 and 0.001, respectively]. Acarbose treatment was associated with decreased muscle mass and strength. Assessment and exercise of muscles in patients with long-term acarbose treatment should be considered." @default.
- W3199300507 created "2021-09-27" @default.
- W3199300507 creator A5023868586 @default.
- W3199300507 creator A5026397596 @default.
- W3199300507 creator A5029979857 @default.
- W3199300507 creator A5063727121 @default.
- W3199300507 creator A5066618638 @default.
- W3199300507 creator A5070820936 @default.
- W3199300507 creator A5081125297 @default.
- W3199300507 creator A5082984382 @default.
- W3199300507 date "2021-09-20" @default.
- W3199300507 modified "2023-10-09" @default.
- W3199300507 title "Association of Acarbose with Decreased Muscle Mass and Function in Patients with Type 2 Diabetes: A Retrospective, Cross-Sectional Study" @default.
- W3199300507 cites W2002457739 @default.
- W3199300507 cites W2011689776 @default.
- W3199300507 cites W2016348064 @default.
- W3199300507 cites W2025076594 @default.
- W3199300507 cites W2044093994 @default.
- W3199300507 cites W2096697496 @default.
- W3199300507 cites W2105398025 @default.
- W3199300507 cites W2119958965 @default.
- W3199300507 cites W2128890254 @default.
- W3199300507 cites W2130668899 @default.
- W3199300507 cites W2131905731 @default.
- W3199300507 cites W2138781309 @default.
- W3199300507 cites W2147848346 @default.
- W3199300507 cites W2170157817 @default.
- W3199300507 cites W2345941496 @default.
- W3199300507 cites W2556532561 @default.
- W3199300507 cites W2563580879 @default.
- W3199300507 cites W2593371426 @default.
- W3199300507 cites W2603906102 @default.
- W3199300507 cites W2747491011 @default.
- W3199300507 cites W2767025486 @default.
- W3199300507 cites W2774437822 @default.
- W3199300507 cites W2801524940 @default.
- W3199300507 cites W2807979624 @default.
- W3199300507 cites W2909187793 @default.
- W3199300507 cites W2918126510 @default.
- W3199300507 cites W2921752535 @default.
- W3199300507 cites W2922486231 @default.
- W3199300507 cites W2946415573 @default.
- W3199300507 cites W2946452366 @default.
- W3199300507 cites W2947859675 @default.
- W3199300507 cites W2954950466 @default.
- W3199300507 cites W2974374436 @default.
- W3199300507 cites W2990309084 @default.
- W3199300507 cites W3000664844 @default.
- W3199300507 cites W3005437800 @default.
- W3199300507 cites W3013047499 @default.
- W3199300507 cites W3119081787 @default.
- W3199300507 cites W4205123661 @default.
- W3199300507 cites W4246340431 @default.
- W3199300507 doi "https://doi.org/10.1007/s13300-021-01151-6" @default.
- W3199300507 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8521566" @default.
- W3199300507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34542866" @default.
- W3199300507 hasPublicationYear "2021" @default.
- W3199300507 type Work @default.
- W3199300507 sameAs 3199300507 @default.
- W3199300507 citedByCount "2" @default.
- W3199300507 countsByYear W31993005072021 @default.
- W3199300507 countsByYear W31993005072022 @default.
- W3199300507 crossrefType "journal-article" @default.
- W3199300507 hasAuthorship W3199300507A5023868586 @default.
- W3199300507 hasAuthorship W3199300507A5026397596 @default.
- W3199300507 hasAuthorship W3199300507A5029979857 @default.
- W3199300507 hasAuthorship W3199300507A5063727121 @default.
- W3199300507 hasAuthorship W3199300507A5066618638 @default.
- W3199300507 hasAuthorship W3199300507A5070820936 @default.
- W3199300507 hasAuthorship W3199300507A5081125297 @default.
- W3199300507 hasAuthorship W3199300507A5082984382 @default.
- W3199300507 hasBestOaLocation W31993005071 @default.
- W3199300507 hasConcept C126322002 @default.
- W3199300507 hasConcept C134018914 @default.
- W3199300507 hasConcept C141071460 @default.
- W3199300507 hasConcept C2776214593 @default.
- W3199300507 hasConcept C2776617576 @default.
- W3199300507 hasConcept C2777180221 @default.
- W3199300507 hasConcept C2777433710 @default.
- W3199300507 hasConcept C2779306644 @default.
- W3199300507 hasConcept C2779959927 @default.
- W3199300507 hasConcept C2780221984 @default.
- W3199300507 hasConcept C2780323712 @default.
- W3199300507 hasConcept C33872192 @default.
- W3199300507 hasConcept C555293320 @default.
- W3199300507 hasConcept C71924100 @default.
- W3199300507 hasConcept C90924648 @default.
- W3199300507 hasConceptScore W3199300507C126322002 @default.
- W3199300507 hasConceptScore W3199300507C134018914 @default.
- W3199300507 hasConceptScore W3199300507C141071460 @default.
- W3199300507 hasConceptScore W3199300507C2776214593 @default.
- W3199300507 hasConceptScore W3199300507C2776617576 @default.
- W3199300507 hasConceptScore W3199300507C2777180221 @default.
- W3199300507 hasConceptScore W3199300507C2777433710 @default.
- W3199300507 hasConceptScore W3199300507C2779306644 @default.
- W3199300507 hasConceptScore W3199300507C2779959927 @default.
- W3199300507 hasConceptScore W3199300507C2780221984 @default.
- W3199300507 hasConceptScore W3199300507C2780323712 @default.
- W3199300507 hasConceptScore W3199300507C33872192 @default.
- W3199300507 hasConceptScore W3199300507C555293320 @default.